These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

304 related articles for article (PubMed ID: 19568652)

  • 1. Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles.
    Sánchez C; Salas AP; Braña AF; Palomino M; Pineda-Lucena A; Carbajo RJ; Méndez C; Moris F; Salas JA
    Chem Commun (Camb); 2009 Jul; (27):4118-20. PubMed ID: 19568652
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TrkA kinase inhibitors from a library of modified and isosteric Staurosporine aglycone.
    Tripathy R; Angeles TS; Yang SX; Mallamo JP
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3551-5. PubMed ID: 18508265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chemical biology of natural indolocarbazole products: 30 years since the discovery of staurosporine.
    Nakano H; Omura S
    J Antibiot (Tokyo); 2009 Jan; 62(1):17-26. PubMed ID: 19132059
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Indolocarbazole antitumour compounds by combinatorial biosynthesis.
    Salas JA; Méndez C
    Curr Opin Chem Biol; 2009 Apr; 13(2):152-60. PubMed ID: 19251468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 1,7-annulated indolocarbazoles as cyclin-dependent kinase inhibitors.
    Al-awar RS; Ray JE; Hecker KA; Huang J; Waid PP; Shih C; Brooks HB; Spencer CD; Watkins SA; Patel BR; Stamm NB; Ogg CA; Schultz RM; Considine EL; Faul MM; Sullivan KA; Kolis SP; Grutsch JL; Joseph S
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3217-20. PubMed ID: 15149678
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins.
    Akue-Gedu R; Debiton E; Ferandin Y; Meijer L; Prudhomme M; Anizon F; Moreau P
    Bioorg Med Chem; 2009 Jul; 17(13):4420-4. PubMed ID: 19477650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and optimisation of novel and selective small molecular weight kinase inhibitors of mTOR.
    Menear KA; Gomez S; Malagu K; Bailey C; Blackburn K; Cockcroft XL; Ewen S; Fundo A; Le Gall A; Hermann G; Sebastian L; Sunose M; Presnot T; Torode E; Hickson I; Martin NM; Smith GC; Pike KG
    Bioorg Med Chem Lett; 2009 Oct; 19(20):5898-901. PubMed ID: 19733066
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Kinase inhibitory potencies and in vitro antiproliferative activities of N-10 substituted pyrrolo[2,3-a]carbazole derivatives.
    Akué-Gédu R; Letribot B; Saugues E; Debiton E; Anizon F; Moreau P
    Bioorg Med Chem Lett; 2012 Jun; 22(11):3807-9. PubMed ID: 22543026
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New indolocarbazoles from a mutant strain of the marine-derived actinomycete Streptomyces fradiae 007M135.
    Fu P; Zhuang Y; Wang Y; Liu P; Qi X; Gu K; Zhang D; Zhu W
    Org Lett; 2012 Dec; 14(24):6194-7. PubMed ID: 23215024
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Combined directed ortho and remote metalation-cross-coupling strategies. General method for benzo[a]carbazoles and the synthesis of an unnamed indolo[2,3-a]carbazole alkaloid.
    Cai X; Snieckus V
    Org Lett; 2004 Jul; 6(14):2293-5. PubMed ID: 15228262
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antiproliferative activity of arborescidine alkaloids and derivatives.
    Santos LS; Theoduloz C; Pilli RA; Rodriguez J
    Eur J Med Chem; 2009 Sep; 44(9):3810-5. PubMed ID: 19419803
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
    Ye Q; Cao J; Zhou X; Lv D; He Q; Yang B; Hu Y
    Bioorg Med Chem; 2009 Jul; 17(13):4763-72. PubMed ID: 19447039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combinatorial biosynthesis of antitumor indolocarbazole compounds.
    Sánchez C; Zhu L; Braña AF; Salas AP; Rohr J; Méndez C; Salas JA
    Proc Natl Acad Sci U S A; 2005 Jan; 102(2):461-6. PubMed ID: 15625109
    [TBL] [Abstract][Full Text] [Related]  

  • 14. It works: combinatorial biosynthesis for generating novel glycosylated compounds.
    Luzhetskyy A; Bechthold A
    Mol Microbiol; 2005 Oct; 58(1):3-5. PubMed ID: 16164544
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The synthesis of bioactive indolocarbazoles related to K-252a.
    Moffat D; Nichols CJ; Riley DA; Simpkins NS
    Org Biomol Chem; 2005 Aug; 3(16):2953-75. PubMed ID: 16186927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase inhibition of clinically important staurosporine analogues.
    Gani OA; Engh RA
    Nat Prod Rep; 2010 Apr; 27(4):489-98. PubMed ID: 20336234
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Spiroindimicins A-D: new bisindole alkaloids from a deep-sea-derived actinomycete.
    Zhang W; Liu Z; Li S; Yang T; Zhang Q; Ma L; Tian X; Zhang H; Huang C; Zhang S; Ju J; Shen Y; Zhang C
    Org Lett; 2012 Jul; 14(13):3364-7. PubMed ID: 22694269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel 5,7-disubstituted 6-amino-5H-pyrrolo[3,2-b]pyrazine-2,3-dicarbonitriles, the promising protein kinase inhibitors with antiproliferative activity.
    Dubinina GG; Platonov MO; Golovach SM; Borysko PO; Tolmachov AO; Volovenko YM
    Eur J Med Chem; 2006 Jun; 41(6):727-37. PubMed ID: 16675067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Streptocarbazoles A and B, two novel indolocarbazoles from the marine-derived actinomycete strain Streptomyces sp. FMA.
    Fu P; Yang C; Wang Y; Liu P; Ma Y; Xu L; Su M; Hong K; Zhu W
    Org Lett; 2012 May; 14(9):2422-5. PubMed ID: 22519738
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Production of chromopyrrolic acid by coexpression of inkOD in a heterologous host Streptomyces albus.
    Chae CS; Park JS; Chung SC; Kim TI; Lee SH; Yoon KM; Shin J; Oh KB
    Bioorg Med Chem Lett; 2009 Mar; 19(6):1581-3. PubMed ID: 19246195
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.