BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 19572551)

  • 1. Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.
    Jacobs CS; Dervan PB
    J Med Chem; 2009 Dec; 52(23):7380-8. PubMed ID: 19572551
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sequence-specific DNA binding Pyrrole-imidazole polyamides and their applications.
    Kawamoto Y; Bando T; Sugiyama H
    Bioorg Med Chem; 2018 May; 26(8):1393-1411. PubMed ID: 29439914
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Orientation preferences of hairpin pyrrole-imidazole polyamides toward
    Sato S; Asamitsu S; Bando T; Sugiyama H
    Bioorg Med Chem; 2019 Jun; 27(11):2167-2171. PubMed ID: 31000407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.
    Meier JL; Montgomery DC; Dervan PB
    Nucleic Acids Res; 2012 Mar; 40(5):2345-56. PubMed ID: 22080545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Binding of hairpin pyrrole and imidazole polyamides to DNA: relationship between torsion angle and association rate constants.
    Han YW; Matsumoto T; Yokota H; Kashiwazaki G; Morinaga H; Hashiya K; Bando T; Harada Y; Sugiyama H
    Nucleic Acids Res; 2012 Dec; 40(22):11510-7. PubMed ID: 23042247
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclic pyrrole-imidazole polyamides targeted to the androgen response element.
    Chenoweth DM; Harki DA; Phillips JW; Dose C; Dervan PB
    J Am Chem Soc; 2009 May; 131(20):7182-8. PubMed ID: 19413319
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rational design of specific binding hairpin Py-Im polyamides targeting human telomere sequences.
    Guo C; Kawamoto Y; Asamitsu S; Sawatani Y; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2015 Feb; 23(4):855-60. PubMed ID: 25614111
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequence-specific DNA binding by long hairpin pyrrole-imidazole polyamides containing an 8-amino-3,6-dioxaoctanoic acid unit.
    Sawatani Y; Kashiwazaki G; Chandran A; Asamitsu S; Guo C; Sato S; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2016 Aug; 24(16):3603-11. PubMed ID: 27301681
    [TBL] [Abstract][Full Text] [Related]  

  • 9. On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides.
    White S; Baird EE; Dervan PB
    Chem Biol; 1997 Aug; 4(8):569-78. PubMed ID: 9281524
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of cyclic Py-Im polyamide libraries.
    Li BC; Montgomery DC; Puckett JW; Dervan PB
    J Org Chem; 2013 Jan; 78(1):124-33. PubMed ID: 23106218
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of single pyrrole replacement with β-alanine on DNA binding affinity and sequence specificity of hairpin pyrrole/imidazole polyamides targeting 5'-GCGC-3'.
    Han YW; Kashiwazaki G; Morinaga H; Matsumoto T; Hashiya K; Bando T; Harada Y; Sugiyama H
    Bioorg Med Chem; 2013 Sep; 21(17):5436-41. PubMed ID: 23810670
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the inverted CCAAT box 2 in the topoisomerase IIalpha promoter by JH-37, an imidazole-pyrrole polyamide hairpin: design, synthesis, molecular biology, and biophysical studies.
    Henry JA; Le NM; Nguyen B; Howard CM; Bailey SL; Horick SM; Buchmueller KL; Kotecha M; Hochhauser D; Hartley JA; Wilson WD; Lee M
    Biochemistry; 2004 Sep; 43(38):12249-57. PubMed ID: 15379563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.
    Wang S; Chai Y; Babu B; Satam V; Lee M; David Wilson W
    J Mol Recognit; 2013 Aug; 26(8):331-40. PubMed ID: 23784989
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel diamino imidazole and pyrrole-containing polyamides: Synthesis and DNA binding studies of mono- and diamino-phenyl-ImPy*Im polyamides designed to target 5'-ACGCGT-3'.
    Satam V; Babu B; Chavda S; Savagian M; Sjoholm R; Tzou S; Ramos J; Liu Y; Kiakos K; Lin S; David Wilson W; Hartley JA; Lee M
    Bioorg Med Chem; 2012 Jan; 20(2):693-701. PubMed ID: 22222156
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.
    Hargrove AE; Martinez TF; Hare AA; Kurmis AA; Phillips JW; Sud S; Pienta KJ; Dervan PB
    PLoS One; 2015; 10(11):e0143161. PubMed ID: 26571387
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography.
    Harki DA; Satyamurthy N; Stout DB; Phelps ME; Dervan PB
    Proc Natl Acad Sci U S A; 2008 Sep; 105(35):13039-44. PubMed ID: 18753620
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA sequence recognition by Hoechst 33258 conjugates of hairpin pyrrole/imidazole polyamides.
    Correa BJ; Canzio D; Kahane AL; Reddy PM; Bruice TC
    Bioorg Med Chem Lett; 2006 Jul; 16(14):3745-50. PubMed ID: 16682192
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif.
    Xu L; Wang W; Gotte D; Yang F; Hare AA; Welch TR; Li BC; Shin JH; Chong J; Strathern JN; Dervan PB; Wang D
    Proc Natl Acad Sci U S A; 2016 Nov; 113(44):12426-12431. PubMed ID: 27791148
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Advances in the chemical and biological studies of polyamides].
    Zhu SL; Gao PH; Li P; Jiang YY; Zhang DZ
    Yao Xue Xue Bao; 2008 Nov; 43(11):1089-93. PubMed ID: 19239025
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI.
    Minoshima M; Bando T; Shinohara K; Kashiwazaki G; Nishijima S; Sugiyama H
    Bioorg Med Chem; 2010 Feb; 18(3):1236-43. PubMed ID: 20074970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.