BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

560 related articles for article (PubMed ID: 19574054)

  • 1. Synthesis, antimalarial activity and cytotoxicity of substituted 3,6-diphenyl-[1,2,4,5]tetraoxanes.
    Kumar N; Khan SI; Beena ; Rajalakshmi G; Kumaradhas P; Rawat DS
    Bioorg Med Chem; 2009 Aug; 17(15):5632-8. PubMed ID: 19574054
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, thermal stability, antimalarial activity of symmetrically and asymmetrically substituted tetraoxanes.
    Atheaya H; Khan SI; Mamgain R; Rawat DS
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1446-9. PubMed ID: 18248990
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and antimalarial activity of dihydroperoxides and tetraoxanes conjugated with bis(benzyl)acetone derivatives.
    Franco LL; de Almeida MV; E Silva LF; Vieira PP; Pohlit AM; Valle MS
    Chem Biol Drug Des; 2012 May; 79(5):790-7. PubMed ID: 22284812
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.
    Ellis GL; Amewu R; Sabbani S; Stocks PA; Shone A; Stanford D; Gibbons P; Davies J; Vivas L; Charnaud S; Bongard E; Hall C; Rimmer K; Lozanom S; Jesús M; Gargallo D; Ward SA; O'Neill PM
    J Med Chem; 2008 Apr; 51(7):2170-7. PubMed ID: 18341274
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone.
    Dong Y; McCullough KJ; Wittlin S; Chollet J; Vennerstrom JL
    Bioorg Med Chem Lett; 2010 Nov; 20(22):6359-61. PubMed ID: 20943385
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chemical stability of the peroxide bond enables diversified synthesis of potent tetraoxane antimalarials.
    Opsenica I; Opsenica D; Smith KS; Milhous WK; Solaja BA
    J Med Chem; 2008 Apr; 51(7):2261-6. PubMed ID: 18330976
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Influence of stereoisomer of dispiro-1,2,4,5-tetraoxanes on their binding mode with heme and on antimalarial activity: molecular docking studies.
    Tonmunphean S; Wijitkosoom A; Tantirungrotechai Y
    Bioorg Med Chem; 2004 May; 12(9):2005-12. PubMed ID: 15080904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and antimalarial activity of 11 dispiro-1,2,4,5-tetraoxane analogues of WR 148999. 7,8,15,16-Tetraoxadispiro[5.2.5.2]hexadecanes substituted at the 1 and 10 positions with unsaturated and polar functional groups.
    Dong Y; Matile H; Chollet J; Kaminsky R; Wood JK; Vennerstrom JL
    J Med Chem; 1999 Apr; 42(8):1477-80. PubMed ID: 10212135
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton.
    Opsenica I; Opsenica D; Lanteri CA; Anova L; Milhous WK; Smith KS; Solaja BA
    J Med Chem; 2008 Oct; 51(19):6216-9. PubMed ID: 18774792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Iodine-catalyzed one-pot synthesis and antimalarial activity evaluation of symmetrically and asymmetrically substituted 3,6-diphenyl[1,2,4,5]tetraoxanes.
    Kumar N; Khan SI; Sharma M; Atheaya H; Rawat DS
    Bioorg Med Chem Lett; 2009 Mar; 19(6):1675-7. PubMed ID: 19231182
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tetraoxane antimalarials and their reaction with Fe(II).
    Opsenica I; Terzić N; Opsenica D; Angelovski G; Lehnig M; Eilbracht P; Tinant B; Juranić Z; Smith KS; Yang YS; Diaz DS; Smith PL; Milhous WK; Doković D; Solaja BA
    J Med Chem; 2006 Jun; 49(13):3790-9. PubMed ID: 16789736
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.
    Amewu RK; Chadwick J; Hussain A; Panda S; Rinki R; Janneh O; Ward SA; Miguel C; Burrell-Saward H; Vivas L; O'Neill PM
    Bioorg Med Chem; 2013 Dec; 21(23):7392-7. PubMed ID: 24148834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deoxycholic acid-derived tetraoxane antimalarials and antiproliferatives(1).
    Terzić N; Opsenica D; Milić D; Tinant B; Smith KS; Milhous WK; Solaja BA
    J Med Chem; 2007 Oct; 50(21):5118-27. PubMed ID: 17887664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.
    O'Neill PM; Amewu RK; Nixon GL; Bousejra ElGarah F; Mungthin M; Chadwick J; Shone AE; Vivas L; Lander H; Barton V; Muangnoicharoen S; Bray PG; Davies J; Park BK; Wittlin S; Brun R; Preschel M; Zhang K; Ward SA
    Angew Chem Int Ed Engl; 2010 Aug; 49(33):5693-7. PubMed ID: 20629058
    [No Abstract]   [Full Text] [Related]  

  • 15. Synthesis, antimalarial activity and cytotoxicity of 4-aminoquinoline-triazine conjugates.
    Manohar S; Khan SI; Rawat DS
    Bioorg Med Chem Lett; 2010 Jan; 20(1):322-5. PubMed ID: 19910192
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and in vitro antimalarial activity of tetraoxane-amine/amide conjugates.
    Kumar N; Khan SI; Atheaya H; Mamgain R; Rawat DS
    Eur J Med Chem; 2011 Jul; 46(7):2816-27. PubMed ID: 21530018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline.
    Delarue-Cochin S; Grellier P; Maes L; Mouray E; Sergheraert C; Melnyk P
    Eur J Med Chem; 2008 Oct; 43(10):2045-55. PubMed ID: 18226428
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of the reactivity of antimalarial 1,2,4,5-tetraoxanes with 1,2,4-trioxolanes in the presence of ferrous iron salts, heme, and ferrous iron salts/phosphatidylcholine.
    Bousejra-El Garah F; Wong MH; Amewu RK; Muangnoicharoen S; Maggs JL; Stigliani JL; Park BK; Chadwick J; Ward SA; O'Neill PM
    J Med Chem; 2011 Oct; 54(19):6443-55. PubMed ID: 21888440
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers).
    Dong Y; Creek D; Chollet J; Matile H; Charman SA; Wittlin S; Wood JK; Vennerstrom JL
    Antimicrob Agents Chemother; 2007 Aug; 51(8):3033-5. PubMed ID: 17485500
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tetraoxanes as antimalarials: harnessing the endoperoxide.
    Fisher LC; Blackie MA
    Mini Rev Med Chem; 2014 Feb; 14(2):123-35. PubMed ID: 24456270
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.