BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 19583488)

  • 1. Cases of borderline in vitro constitutive thyrotropin receptor activity: how to decide whether a thyrotropin receptor mutation is constitutively active or not?
    Mueller S; Gozu HI; Bircan R; Jaeschke H; Eszlinger M; Lueblinghoff J; Krohn K; Paschke R
    Thyroid; 2009 Jul; 19(7):765-73. PubMed ID: 19583488
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Current standards, variations, and pitfalls for the determination of constitutive TSHR activity in vitro.
    Mueller S; Jaeschke H; Paschke R
    Methods Enzymol; 2010; 485():421-36. PubMed ID: 21050930
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shared sporadic and somatic thyrotropin receptor mutations display more active in vitro activities than familial thyrotropin receptor mutations.
    Lueblinghoff J; Eszlinger M; Jaeschke H; Mueller S; Bircan R; Gozu H; Sancak S; Akalin S; Paschke R
    Thyroid; 2011 Mar; 21(3):221-9. PubMed ID: 21190443
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Functional characterization of five constitutively activating thyrotrophin receptor mutations.
    Wonerow P; Chey S; Führer D; Holzapfel HP; Paschke R
    Clin Endocrinol (Oxf); 2000 Oct; 53(4):461-8. PubMed ID: 11012571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations in the mouse TSH receptor equivalent to human constitutively activating TSH receptor mutations also cause constitutive activity.
    Neumann S; Krohn K; Chey S; Paschke R
    Horm Metab Res; 2001 May; 33(5):263-9. PubMed ID: 11440271
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and functional characterization of two novel activating thyrotropin receptor mutants in toxic thyroid follicular adenomas.
    Castro I; Lima L; Seoane R; Lado-Abeal J
    Thyroid; 2009 Jun; 19(6):645-9. PubMed ID: 19499991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A new silent germline mutation of the TSH receptor: coexpression in a hyperthyroid family member with a second activating somatic mutation.
    Gozu HI; Mueller S; Bircan R; Krohn K; Ekinci G; Yavuzer D; Sargin H; Sargin M; Ones T; Gezen C; Orbay E; Cirakoglu B; Paschke R
    Thyroid; 2008 May; 18(5):499-508. PubMed ID: 18466076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional significance of the thyrotropin receptor germline polymorphism D727E.
    Sykiotis GP; Neumann S; Georgopoulos NA; Sgourou A; Papachatzopoulou A; Markou KB; Kyriazopoulou V; Paschke R; Vagenakis AG; Papavassiliou AG
    Biochem Biophys Res Commun; 2003 Feb; 301(4):1051-6. PubMed ID: 12589819
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lack of in vitro constitutive activity for four previously reported TSH receptor mutations identified in patients with nonautoimmune hyperthyroidism and hot thyroid carcinomas.
    Jaeschke H; Mueller S; Eszlinger M; Paschke R
    Clin Endocrinol (Oxf); 2010 Dec; 73(6):815-20. PubMed ID: 20846293
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutive activation of the thyrotropin receptor by deletion of a portion of the extracellular domain.
    Zhang ML; Sugawa H; Kosugi S; Mori T
    Biochem Biophys Res Commun; 1995 Jun; 211(1):205-10. PubMed ID: 7779086
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interactions between the extracellular domain and the extracellular loops as well as the 6th transmembrane domain are necessary for TSH receptor activation.
    Neumann S; Claus M; Paschke R
    Eur J Endocrinol; 2005 Apr; 152(4):625-34. PubMed ID: 15817920
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S; Okajima F; Ban T; Hidaka A; Shenker A; Kohn LD
    Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells.
    Agretti P; De Marco G; Pinchera A; Vitti P; Bernal J; Tonacchera M
    J Endocrinol Invest; 2007 Apr; 30(4):279-84. PubMed ID: 17556863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Proper targeting and activity of a nonfunctioning thyroid-stimulating hormone receptor (TSHr) combining an inactivating and activating TSHr mutation in one receptor.
    Agretti P; De Marco G; Collecchi P; Chiovato L; Vitti P; Pinchera A; Tonacchera M
    Eur J Biochem; 2003 Sep; 270(18):3839-47. PubMed ID: 12950268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors.
    Cetani F; Tonacchera M; Vassart G
    FEBS Lett; 1996 Jan; 378(1):27-31. PubMed ID: 8549796
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Germline mutations of TSH receptor gene as cause of nonautoimmune subclinical hypothyroidism.
    Alberti L; Proverbio MC; Costagliola S; Romoli R; Boldrighini B; Vigone MC; Weber G; Chiumello G; Beck-Peccoz P; Persani L
    J Clin Endocrinol Metab; 2002 Jun; 87(6):2549-55. PubMed ID: 12050212
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive activation of the thyroid-stimulating hormone receptor (TSHR) by mutating Ile691 in the cytoplasmic tail segment.
    Liu Z; Fan F; Xiao X; Sun Y
    PLoS One; 2011 Jan; 6(1):e16335. PubMed ID: 21283701
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane appears to be an uncompetitive inverse agonist for the thyrotropin receptor.
    Rossi M; Dimida A; Dell'anno MT; Trincavelli ML; Agretti P; Giorgi F; Corsini GU; Pinchera A; Vitti P; Tonacchera M; Maggio R
    J Pharmacol Exp Ther; 2007 Jan; 320(1):465-74. PubMed ID: 17062616
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel thyrotropin receptor germline mutation (Ile568Val) in a Saxonian family with hereditary nonautoimmune hyperthyroidism.
    Claus M; Maier J; Paschke R; Kujat C; Stumvoll M; Führer D
    Thyroid; 2005 Sep; 15(9):1089-94. PubMed ID: 16187920
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.
    Biebermann H; Winkler F; Handke D; Teichmann A; Gerling B; Cameron F; Eichhorst J; Grüters A; Wiesner B; Kühnen P; Krude H; Kleinau G
    J Clin Endocrinol Metab; 2012 Feb; 97(2):E228-32. PubMed ID: 22112806
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.