These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 19587019)

  • 1. A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation.
    Masuda K; Ouchida R; Li Y; Gao X; Mori H; Wang JY
    J Immunol; 2009 Aug; 183(3):1846-50. PubMed ID: 19587019
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation.
    Kano C; Hanaoka F; Wang JY
    Int Immunol; 2012 Mar; 24(3):169-74. PubMed ID: 22223762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice.
    Jansen JG; Langerak P; Tsaalbi-Shtylik A; van den Berk P; Jacobs H; de Wind N
    J Exp Med; 2006 Feb; 203(2):319-23. PubMed ID: 16476771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.
    Masuda K; Ouchida R; Hikida M; Kurosaki T; Yokoi M; Masutani C; Seki M; Wood RD; Hanaoka F; O-Wang J
    J Biol Chem; 2007 Jun; 282(24):17387-94. PubMed ID: 17449470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40.
    Ross AL; Sale JE
    Mol Immunol; 2006 Apr; 43(10):1587-94. PubMed ID: 16263170
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
    Masuda K; Ouchida R; Takeuchi A; Saito T; Koseki H; Kawamura K; Tagawa M; Tokuhisa T; Azuma T; O-Wang J
    Proc Natl Acad Sci U S A; 2005 Sep; 102(39):13986-91. PubMed ID: 16172387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.
    Krijger PH; Tsaalbi-Shtylik A; Wit N; van den Berk PC; de Wind N; Jacobs H
    Eur J Immunol; 2013 Oct; 43(10):2765-70. PubMed ID: 23857323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes.
    Masuda K; Ouchida R; Hikida M; Nakayama M; Ohara O; Kurosaki T; O-Wang J
    DNA Repair (Amst); 2006 Nov; 5(11):1384-91. PubMed ID: 16890500
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
    Li S; Zhao Y; Wang JY
    Mol Immunol; 2013 Mar; 53(3):214-7. PubMed ID: 22960197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation.
    Masuda K; Ouchida R; Yokoi M; Hanaoka F; Azuma T; Wang JY
    Eur J Immunol; 2008 Oct; 38(10):2796-805. PubMed ID: 18825746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.
    Zan H; Cerutti A; Dramitinos P; Schaffer A; Li Z; Casali P
    J Immunol; 1999 Mar; 162(6):3437-47. PubMed ID: 10092799
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of deoxycytidyl transferase activity of yeast Rev1 protein in the bypass of abasic sites.
    Otsuka C; Loakes D; Negishi K
    Nucleic Acids Res Suppl; 2002; (2):87-8. PubMed ID: 12903118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.
    Martomo SA; Yang WW; Vaisman A; Maas A; Yokoi M; Hoeijmakers JH; Hanaoka F; Woodgate R; Gearhart PJ
    DNA Repair (Amst); 2006 Mar; 5(3):392-8. PubMed ID: 16443401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.
    Martomo SA; Saribasak H; Yokoi M; Hanaoka F; Gearhart PJ
    DNA Repair (Amst); 2008 Sep; 7(9):1603-8. PubMed ID: 18485835
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.
    Mayorov VI; Rogozin IB; Adkison LR; Frahm C; Kunkel TA; Pavlov YI
    BMC Immunol; 2005 Jun; 6():10. PubMed ID: 15949042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice.
    Rada C; Williams GT; Nilsen H; Barnes DE; Lindahl T; Neuberger MS
    Curr Biol; 2002 Oct; 12(20):1748-55. PubMed ID: 12401169
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rev1 is a base excision repair enzyme with 5'-deoxyribose phosphate lyase activity.
    Prasad R; Poltoratsky V; Hou EW; Wilson SH
    Nucleic Acids Res; 2016 Dec; 44(22):10824-10833. PubMed ID: 27683219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes.
    Sabouri Z; Okazaki IM; Shinkura R; Begum N; Nagaoka H; Tsuchimoto D; Nakabeppu Y; Honjo T
    Int Immunol; 2009 Aug; 21(8):947-55. PubMed ID: 19556307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination.
    Martomo SA; Yang WW; Gearhart PJ
    J Exp Med; 2004 Jul; 200(1):61-8. PubMed ID: 15238605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hijacked DNA repair proteins and unchained DNA polymerases.
    Saribasak H; Rajagopal D; Maul RW; Gearhart PJ
    Philos Trans R Soc Lond B Biol Sci; 2009 Mar; 364(1517):605-11. PubMed ID: 19008198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.