BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 19587019)

  • 1. A critical role for REV1 in regulating the induction of C:G transitions and A:T mutations during Ig gene hypermutation.
    Masuda K; Ouchida R; Li Y; Gao X; Mori H; Wang JY
    J Immunol; 2009 Aug; 183(3):1846-50. PubMed ID: 19587019
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of mice deficient in both REV1 catalytic activity and POLH reveals an unexpected role for POLH in the generation of C to G and G to C transversions during Ig gene hypermutation.
    Kano C; Hanaoka F; Wang JY
    Int Immunol; 2012 Mar; 24(3):169-74. PubMed ID: 22223762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strand-biased defect in C/G transversions in hypermutating immunoglobulin genes in Rev1-deficient mice.
    Jansen JG; Langerak P; Tsaalbi-Shtylik A; van den Berk P; Jacobs H; de Wind N
    J Exp Med; 2006 Feb; 203(2):319-23. PubMed ID: 16476771
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA polymerases eta and theta function in the same genetic pathway to generate mutations at A/T during somatic hypermutation of Ig genes.
    Masuda K; Ouchida R; Hikida M; Kurosaki T; Yokoi M; Masutani C; Seki M; Wood RD; Hanaoka F; O-Wang J
    J Biol Chem; 2007 Jun; 282(24):17387-94. PubMed ID: 17449470
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The catalytic activity of REV1 is employed during immunoglobulin gene diversification in DT40.
    Ross AL; Sale JE
    Mol Immunol; 2006 Apr; 43(10):1587-94. PubMed ID: 16263170
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA polymerase theta contributes to the generation of C/G mutations during somatic hypermutation of Ig genes.
    Masuda K; Ouchida R; Takeuchi A; Saito T; Koseki H; Kawamura K; Tagawa M; Tokuhisa T; Azuma T; O-Wang J
    Proc Natl Acad Sci U S A; 2005 Sep; 102(39):13986-91. PubMed ID: 16172387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.
    Krijger PH; Tsaalbi-Shtylik A; Wit N; van den Berk PC; de Wind N; Jacobs H
    Eur J Immunol; 2013 Oct; 43(10):2765-70. PubMed ID: 23857323
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Absence of DNA polymerase theta results in decreased somatic hypermutation frequency and altered mutation patterns in Ig genes.
    Masuda K; Ouchida R; Hikida M; Nakayama M; Ohara O; Kurosaki T; O-Wang J
    DNA Repair (Amst); 2006 Nov; 5(11):1384-91. PubMed ID: 16890500
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of Ig gene hypermutation in Ung(-/-)Polh(-/-) mice suggests that UNG and A:T mutagenesis pathway target different U:G lesions.
    Li S; Zhao Y; Wang JY
    Mol Immunol; 2013 Mar; 53(3):214-7. PubMed ID: 22960197
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA polymerase eta is a limiting factor for A:T mutations in Ig genes and contributes to antibody affinity maturation.
    Masuda K; Ouchida R; Yokoi M; Hanaoka F; Azuma T; Wang JY
    Eur J Immunol; 2008 Oct; 38(10):2796-805. PubMed ID: 18825746
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of Ig somatic hypermutation and class switching in a human monoclonal IgM+ IgD+ B cell line in vitro: definition of the requirements and modalities of hypermutation.
    Zan H; Cerutti A; Dramitinos P; Schaffer A; Li Z; Casali P
    J Immunol; 1999 Mar; 162(6):3437-47. PubMed ID: 10092799
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of deoxycytidyl transferase activity of yeast Rev1 protein in the bypass of abasic sites.
    Otsuka C; Loakes D; Negishi K
    Nucleic Acids Res Suppl; 2002; (2):87-8. PubMed ID: 12903118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.
    Martomo SA; Yang WW; Vaisman A; Maas A; Yokoi M; Hoeijmakers JH; Hanaoka F; Woodgate R; Gearhart PJ
    DNA Repair (Amst); 2006 Mar; 5(3):392-8. PubMed ID: 16443401
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reevaluation of the role of DNA polymerase theta in somatic hypermutation of immunoglobulin genes.
    Martomo SA; Saribasak H; Yokoi M; Hanaoka F; Gearhart PJ
    DNA Repair (Amst); 2008 Sep; 7(9):1603-8. PubMed ID: 18485835
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes.
    Mayorov VI; Rogozin IB; Adkison LR; Frahm C; Kunkel TA; Pavlov YI
    BMC Immunol; 2005 Jun; 6():10. PubMed ID: 15949042
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunoglobulin isotype switching is inhibited and somatic hypermutation perturbed in UNG-deficient mice.
    Rada C; Williams GT; Nilsen H; Barnes DE; Lindahl T; Neuberger MS
    Curr Biol; 2002 Oct; 12(20):1748-55. PubMed ID: 12401169
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rev1 is a base excision repair enzyme with 5'-deoxyribose phosphate lyase activity.
    Prasad R; Poltoratsky V; Hou EW; Wilson SH
    Nucleic Acids Res; 2016 Dec; 44(22):10824-10833. PubMed ID: 27683219
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apex2 is required for efficient somatic hypermutation but not for class switch recombination of immunoglobulin genes.
    Sabouri Z; Okazaki IM; Shinkura R; Begum N; Nagaoka H; Tsuchimoto D; Nakabeppu Y; Honjo T
    Int Immunol; 2009 Aug; 21(8):947-55. PubMed ID: 19556307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A role for Msh6 but not Msh3 in somatic hypermutation and class switch recombination.
    Martomo SA; Yang WW; Gearhart PJ
    J Exp Med; 2004 Jul; 200(1):61-8. PubMed ID: 15238605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hijacked DNA repair proteins and unchained DNA polymerases.
    Saribasak H; Rajagopal D; Maul RW; Gearhart PJ
    Philos Trans R Soc Lond B Biol Sci; 2009 Mar; 364(1517):605-11. PubMed ID: 19008198
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.