BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

652 related articles for article (PubMed ID: 19588966)

  • 1. Reduced or diminished stabilization of the telomere G-quadruplex and inhibition of telomerase by small chemical ligands under molecular crowding condition.
    Chen Z; Zheng KW; Hao YH; Tan Z
    J Am Chem Soc; 2009 Aug; 131(30):10430-8. PubMed ID: 19588966
    [TBL] [Abstract][Full Text] [Related]  

  • 2. G-quadruplex preferentially forms at the very 3' end of vertebrate telomeric DNA.
    Tang J; Kan ZY; Yao Y; Wang Q; Hao YH; Tan Z
    Nucleic Acids Res; 2008 Mar; 36(4):1200-8. PubMed ID: 18158301
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Contribution of telomere G-quadruplex stabilization to the inhibition of telomerase-mediated telomere extension by chemical ligands.
    Chen CY; Wang Q; Liu JQ; Hao YH; Tan Z
    J Am Chem Soc; 2011 Sep; 133(38):15036-44. PubMed ID: 21846102
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-quadruplex formation in human telomeric (TTAGGG)4 sequence with complementary strand in close vicinity under molecularly crowded condition.
    Kan ZY; Lin Y; Wang F; Zhuang XY; Zhao Y; Pang DW; Hao YH; Tan Z
    Nucleic Acids Res; 2007; 35(11):3646-53. PubMed ID: 17488850
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Human telomeric DNA forms parallel-stranded intramolecular G-quadruplex in K+ solution under molecular crowding condition.
    Xue Y; Kan ZY; Wang Q; Yao Y; Liu J; Hao YH; Tan Z
    J Am Chem Soc; 2007 Sep; 129(36):11185-91. PubMed ID: 17705383
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Affinity and selectivity of G4 ligands measured by FRET.
    De Cian A; Guittat L; Shin-ya K; Riou JF; Mergny JL
    Nucleic Acids Symp Ser (Oxf); 2005; (49):235-6. PubMed ID: 17150720
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands.
    Moorhouse AD; Haider S; Gunaratnam M; Munnur D; Neidle S; Moses JE
    Mol Biosyst; 2008 Jun; 4(6):629-42. PubMed ID: 18493662
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Fluorescence-based melting assays for studying quadruplex ligands.
    De Cian A; Guittat L; Kaiser M; Saccà B; Amrane S; Bourdoncle A; Alberti P; Teulade-Fichou MP; Lacroix L; Mergny JL
    Methods; 2007 Jun; 42(2):183-95. PubMed ID: 17472900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [G-quadruplex DNA: myth or reality?].
    Riou JF; Gomez D; Lemarteleur T; Trentesaux C
    Bull Cancer; 2003 Apr; 90(4):305-13. PubMed ID: 12801813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Symmetrical bisbenzimidazoles with benzenediyl spacer: the role of the shape of the ligand on the stabilization and structural alterations in telomeric G-quadruplex DNA and telomerase inhibition.
    Bhattacharya S; Chaudhuri P; Jain AK; Paul A
    Bioconjug Chem; 2010 Jul; 21(7):1148-59. PubMed ID: 20536245
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase.
    Gomez D; Aouali N; Renaud A; Douarre C; Shin-Ya K; Tazi J; Martinez S; Trentesaux C; Morjani H; Riou JF
    Cancer Res; 2003 Oct; 63(19):6149-53. PubMed ID: 14559794
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An exonuclease I hydrolysis assay for evaluating G-quadruplex stabilization by small molecules.
    Yao Y; Wang Q; Hao YH; Tan Z
    Nucleic Acids Res; 2007; 35(9):e68. PubMed ID: 17426118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands.
    Ma Y; Ou TM; Tan JH; Hou JQ; Huang SL; Gu LQ; Huang ZS
    Bioorg Med Chem Lett; 2009 Jul; 19(13):3414-7. PubMed ID: 19477640
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Study on effects of molecular crowding on G-quadruplex-ligand binding and ligand-mediated telomerase inhibition.
    Yaku H; Murashima T; Tateishi-Karimata H; Nakano S; Miyoshi D; Sugimoto N
    Methods; 2013 Nov; 64(1):19-27. PubMed ID: 23562626
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A new steroid derivative stabilizes g-quadruplexes and induces telomere uncapping in human tumor cells.
    Brassart B; Gomez D; De Cian A; Paterski R; Montagnac A; Qui KH; Temime-Smaali N; Trentesaux C; Mergny JL; Gueritte F; Riou JF
    Mol Pharmacol; 2007 Sep; 72(3):631-40. PubMed ID: 17586599
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.
    Mergny JL; Lacroix L; Teulade-Fichou MP; Hounsou C; Guittat L; Hoarau M; Arimondo PB; Vigneron JP; Lehn JM; Riou JF; Garestier T; Hélène C
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3062-7. PubMed ID: 11248032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Label-free electrochemical selection of G-quadruplex-binding ligands based on structure switching.
    Jin Y; Li H; Liu P
    Biosens Bioelectron; 2010 Aug; 25(12):2669-74. PubMed ID: 20488688
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thermally induced DNA.RNA hybrid to G-quadruplex transitions: possible implications for telomere synthesis by telomerase.
    Salazar M; Thompson BD; Kerwin SM; Hurley LH
    Biochemistry; 1996 Dec; 35(50):16110-5. PubMed ID: 8973182
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacodynamics of the G-quadruplex-stabilizing telomerase inhibitor 3,11-difluoro-6,8,13-trimethyl-8H-quino[4,3,2-kl]acridinium methosulfate (RHPS4) in vitro: activity in human tumor cells correlates with telomere length and can be enhanced, or antagonized, with cytotoxic agents.
    Cookson JC; Dai F; Smith V; Heald RA; Laughton CA; Stevens MF; Burger AM
    Mol Pharmacol; 2005 Dec; 68(6):1551-8. PubMed ID: 16150933
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands.
    Pennarun G; Granotier C; Gauthier LR; Gomez D; Hoffschir F; Mandine E; Riou JF; Mergny JL; Mailliet P; Boussin FD
    Oncogene; 2005 Apr; 24(18):2917-28. PubMed ID: 15735722
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.