BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 19589876)

  • 1. Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene.
    Olson KC; Dellinger RW; Zhong Q; Sun D; Amin S; Spratt TE; Lazarus P
    Drug Metab Dispos; 2009 Oct; 37(10):1999-2007. PubMed ID: 19589876
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.
    Villeneuve L; Girard H; Fortier LC; Gagné JF; Guillemette C
    J Pharmacol Exp Ther; 2003 Oct; 307(1):117-28. PubMed ID: 12944498
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.
    Girard H; Court MH; Bernard O; Fortier LC; Villeneuve L; Hao Q; Greenblatt DJ; von Moltke LL; Perussed L; Guillemette C
    Pharmacogenetics; 2004 Aug; 14(8):501-15. PubMed ID: 15284532
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterizing the effect of UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A9 genetic polymorphisms on enantioselective glucuronidation of flurbiprofen.
    Wang H; Yuan L; Zeng S
    Biochem Pharmacol; 2011 Dec; 82(11):1757-63. PubMed ID: 21856293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of D256N and Y483D on propofol glucuronidation by human uridine 5'-diphosphate glucuronosyltransferase (UGT1A9).
    Takahashi H; Maruo Y; Mori A; Iwai M; Sato H; Takeuchi Y
    Basic Clin Pharmacol Toxicol; 2008 Aug; 103(2):131-6. PubMed ID: 18816295
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.
    Jinno H; Saeki M; Saito Y; Tanaka-Kagawa T; Hanioka N; Sai K; Kaniwa N; Ando M; Shirao K; Minami H; Ohtsu A; Yoshida T; Saijo N; Ozawa S; Sawada J
    J Pharmacol Exp Ther; 2003 Aug; 306(2):688-93. PubMed ID: 12730278
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations.
    Mehlotra RK; Bockarie MJ; Zimmerman PA
    Eur J Clin Pharmacol; 2007 Jan; 63(1):1-8. PubMed ID: 17115150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Association analysis of UGT1A genotype and haplotype with SN-38 glucuronidation in human livers.
    Wang H; Bian T; Jin T; Chen Y; Lin A; Chen C
    Pharmacogenomics; 2014 Apr; 15(6):785-98. PubMed ID: 24897286
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Meta-Analysis of Noncompartmental Pharmacokinetic Parameters of Ertugliflozin to Evaluate Dose Proportionality and UGT1A9 Polymorphism Effect on Exposure.
    Marshall JC; Liang Y; Sahasrabudhe V; Tensfeldt T; Fediuk DJ; Zhou S; Krishna R; Dawra VK; Wood LS; Sweeney K
    J Clin Pharmacol; 2021 Sep; 61(9):1220-1231. PubMed ID: 33813736
    [TBL] [Abstract][Full Text] [Related]  

  • 10. UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.
    Girard H; Butler LM; Villeneuve L; Millikan RC; Sinha R; Sandler RS; Guillemette C
    Mutat Res; 2008 Sep; 644(1-2):56-63. PubMed ID: 18675828
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.
    Ehmer U; Vogel A; Schütte JK; Krone B; Manns MP; Strassburg CP
    Hepatology; 2004 Apr; 39(4):970-7. PubMed ID: 15057901
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.
    Korprasertthaworn P; Rowland A; Lewis BC; Mackenzie PI; Yoovathaworn K; Miners JO
    Biochem Pharmacol; 2012 Dec; 84(11):1511-21. PubMed ID: 22981363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genotype and allele frequencies of polymorphic UGT1A9 in the Polish population.
    Zakerska O; Skrzypczak-Zielinska M; Mikstacki A; Tamowicz B; Malengowska B; Szalata M; Slomski R
    Eur J Drug Metab Pharmacokinet; 2013 Sep; 38(3):217-21. PubMed ID: 23184343
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Haplotypes of variants in the UDP-glucuronosyltransferase1A9 and 1A1 genes.
    Innocenti F; Liu W; Chen P; Desai AA; Das S; Ratain MJ
    Pharmacogenet Genomics; 2005 May; 15(5):295-301. PubMed ID: 15864130
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese.
    Saito Y; Sai K; Maekawa K; Kaniwa N; Shirao K; Hamaguchi T; Yamamoto N; Kunitoh H; Ohe Y; Yamada Y; Tamura T; Yoshida T; Minami H; Ohtsu A; Matsumura Y; Saijo N; Sawada J
    Drug Metab Dispos; 2009 Feb; 37(2):272-6. PubMed ID: 18981166
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lack of association between common polymorphisms in UGT1A9 and gene expression and activity.
    Ramírez J; Liu W; Mirkov S; Desai AA; Chen P; Das S; Innocenti F; Ratain MJ
    Drug Metab Dispos; 2007 Dec; 35(12):2149-53. PubMed ID: 17761781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Association of UDP-glucuronosyltransferase 1A9 polymorphisms with adverse reactions to catechol-O-methyltransferase inhibitors in Parkinson's disease patients.
    Ferrari M; Martignoni E; Blandini F; Riboldazzi G; Bono G; Marino F; Cosentino M
    Eur J Clin Pharmacol; 2012 Nov; 68(11):1493-9. PubMed ID: 22527346
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Three novel single nucleotide polymorphisms of UGT1A9 in a Thai population.
    Korprasertthaworn P; Udomuksorn W; Yoovathaworn K
    Drug Metab Pharmacokinet; 2009; 24(5):482-5. PubMed ID: 19881262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure.
    Court MH; Freytsis M; Wang X; Peter I; Guillemette C; Hazarika S; Duan SX; Greenblatt DJ; Lee WM;
    J Pharmacol Exp Ther; 2013 May; 345(2):297-307. PubMed ID: 23408116
    [TBL] [Abstract][Full Text] [Related]  

  • 20. C-440T/T-331C polymorphisms in the UGT1A9 gene affect the pharmacokinetics of mycophenolic acid in kidney transplantation.
    Baldelli S; Merlini S; Perico N; Nicastri A; Cortinovis M; Gotti E; Remuzzi G; Cattaneo D
    Pharmacogenomics; 2007 Sep; 8(9):1127-41. PubMed ID: 17924828
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.