269 related articles for article (PubMed ID: 19596788)
1. The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.
Guo S; Copps KD; Dong X; Park S; Cheng Z; Pocai A; Rossetti L; Sajan M; Farese RV; White MF
Mol Cell Biol; 2009 Sep; 29(18):5070-83. PubMed ID: 19596788
[TBL] [Abstract][Full Text] [Related]
2. PGC1A regulates the IRS1:IRS2 ratio during fasting to influence hepatic metabolism downstream of insulin.
Besse-Patin A; Jeromson S; Levesque-Damphousse P; Secco B; Laplante M; Estall JL
Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4285-4290. PubMed ID: 30770439
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of PTP1B restores IRS1-mediated hepatic insulin signaling in IRS2-deficient mice.
González-Rodríguez A; Mas Gutierrez JA; Sanz-González S; Ros M; Burks DJ; Valverde AM
Diabetes; 2010 Mar; 59(3):588-99. PubMed ID: 20028942
[TBL] [Abstract][Full Text] [Related]
4. Irs1 and Irs2 signaling is essential for hepatic glucose homeostasis and systemic growth.
Dong X; Park S; Lin X; Copps K; Yi X; White MF
J Clin Invest; 2006 Jan; 116(1):101-14. PubMed ID: 16374520
[TBL] [Abstract][Full Text] [Related]
5. Divergent Roles of IRS (Insulin Receptor Substrate) 1 and 2 in Liver and Skeletal Muscle.
Eckstein SS; Weigert C; Lehmann R
Curr Med Chem; 2017; 24(17):1827-1852. PubMed ID: 28462703
[TBL] [Abstract][Full Text] [Related]
6. Inactivation of hepatic Foxo1 by insulin signaling is required for adaptive nutrient homeostasis and endocrine growth regulation.
Dong XC; Copps KD; Guo S; Li Y; Kollipara R; DePinho RA; White MF
Cell Metab; 2008 Jul; 8(1):65-76. PubMed ID: 18590693
[TBL] [Abstract][Full Text] [Related]
7. Effect of dehydroepiandrosterone (DHEA) on Akt and protein kinase C zeta (PKCζ) phosphorylation in different tissues of C57BL6, insulin receptor substrate (IRS)1(-/-), and IRS2(-/-) male mice fed a high-fat diet.
Aoki K; Tajima K; Taguri M; Terauchi Y
J Steroid Biochem Mol Biol; 2016 May; 159():110-20. PubMed ID: 26976654
[TBL] [Abstract][Full Text] [Related]
8. Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance.
Qi Y; Xu Z; Zhu Q; Thomas C; Kumar R; Feng H; Dostal DE; White MF; Baker KM; Guo S
Diabetes; 2013 Nov; 62(11):3887-900. PubMed ID: 24159000
[TBL] [Abstract][Full Text] [Related]
9. Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.
Xuan S; Szabolcs M; Cinti F; Perincheri S; Accili D; Efstratiadis A
J Biol Chem; 2010 Dec; 285(52):41044-50. PubMed ID: 20947509
[TBL] [Abstract][Full Text] [Related]
10. Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.
Kubota N; Kubota T; Itoh S; Kumagai H; Kozono H; Takamoto I; Mineyama T; Ogata H; Tokuyama K; Ohsugi M; Sasako T; Moroi M; Sugi K; Kakuta S; Iwakura Y; Noda T; Ohnishi S; Nagai R; Tobe K; Terauchi Y; Ueki K; Kadowaki T
Cell Metab; 2008 Jul; 8(1):49-64. PubMed ID: 18590692
[TBL] [Abstract][Full Text] [Related]
11. Irs1 serine 307 promotes insulin sensitivity in mice.
Copps KD; Hancer NJ; Opare-Ado L; Qiu W; Walsh C; White MF
Cell Metab; 2010 Jan; 11(1):84-92. PubMed ID: 20074531
[TBL] [Abstract][Full Text] [Related]
12. Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways.
Long YC; Cheng Z; Copps KD; White MF
Mol Cell Biol; 2011 Feb; 31(3):430-41. PubMed ID: 21135130
[TBL] [Abstract][Full Text] [Related]
13. Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.
Kubota N; Kubota T; Kajiwara E; Iwamura T; Kumagai H; Watanabe T; Inoue M; Takamoto I; Sasako T; Kumagai K; Kohjima M; Nakamuta M; Moroi M; Sugi K; Noda T; Terauchi Y; Ueki K; Kadowaki T
Nat Commun; 2016 Oct; 7():12977. PubMed ID: 27708333
[TBL] [Abstract][Full Text] [Related]
14. Liver-specific deletion of insulin receptor substrate 2 does not impair hepatic glucose and lipid metabolism in mice.
Simmgen M; Knauf C; Lopez M; Choudhury AI; Charalambous M; Cantley J; Bedford DC; Claret M; Iglesias MA; Heffron H; Cani PD; Vidal-Puig A; Burcelin R; Withers DJ
Diabetologia; 2006 Mar; 49(3):552-61. PubMed ID: 16404553
[TBL] [Abstract][Full Text] [Related]
15. Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3.
Kawaguchi T; Yoshida T; Harada M; Hisamoto T; Nagao Y; Ide T; Taniguchi E; Kumemura H; Hanada S; Maeyama M; Baba S; Koga H; Kumashiro R; Ueno T; Ogata H; Yoshimura A; Sata M
Am J Pathol; 2004 Nov; 165(5):1499-508. PubMed ID: 15509521
[TBL] [Abstract][Full Text] [Related]
16. IRS1 and IRS2: molecular characterization, tissue expression and transcriptional regulation by insulin in yellow catfish Pelteobagrus fulvidraco.
Zhuo MQ; Pan YX; Wu K; Xu YH; Zhang LH; Luo Z
Fish Physiol Biochem; 2017 Apr; 43(2):619-630. PubMed ID: 27864748
[TBL] [Abstract][Full Text] [Related]
17. FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance.
Stöhr O; Tao R; Miao J; Copps KD; White MF
Cell Rep; 2021 Mar; 34(12):108893. PubMed ID: 33761350
[TBL] [Abstract][Full Text] [Related]
18. Dietary protein deprivation upregulates insulin signaling and inhibits gluconeogenesis in rat liver.
Toyoshima Y; Tokita R; Ohne Y; Hakuno F; Noguchi T; Minami S; Kato H; Takahashi S
J Mol Endocrinol; 2010 Nov; 45(5):329-40. PubMed ID: 20801894
[TBL] [Abstract][Full Text] [Related]
19. The reciprocal stability of FOXO1 and IRS2 creates a regulatory circuit that controls insulin signaling.
Guo S; Dunn SL; White MF
Mol Endocrinol; 2006 Dec; 20(12):3389-99. PubMed ID: 16916938
[TBL] [Abstract][Full Text] [Related]
20. Roles of Insulin Receptor Substrates (IRS) in renal function and renal hemodynamics.
Hashimoto S; Maoka T; Kawata T; Mochizuki T; Koike T; Shigematsu T
PLoS One; 2020; 15(12):e0242332. PubMed ID: 33270683
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
