BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

719 related articles for article (PubMed ID: 19601575)

  • 1. Formation of a unique end-to-end stacked pair of G-quadruplexes in the hTERT core promoter with implications for inhibition of telomerase by G-quadruplex-interactive ligands.
    Palumbo SL; Ebbinghaus SW; Hurley LH
    J Am Chem Soc; 2009 Aug; 131(31):10878-91. PubMed ID: 19601575
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The hTERT core promoter forms three parallel G-quadruplexes.
    Monsen RC; DeLeeuw L; Dean WL; Gray RD; Sabo TM; Chakravarthy S; Chaires JB; Trent JO
    Nucleic Acids Res; 2020 Jun; 48(10):5720-5734. PubMed ID: 32083666
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Self-organization of G-quadruplex structures in the hTERT core promoter stabilized by polyaminic side chain perylene derivatives.
    Micheli E; Martufi M; Cacchione S; De Santis P; Savino M
    Biophys Chem; 2010 Dec; 153(1):43-53. PubMed ID: 21036459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An improved model for the hTERT promoter quadruplex.
    Chaires JB; Trent JO; Gray RD; Dean WL; Buscaglia R; Thomas SD; Miller DM
    PLoS One; 2014; 9(12):e115580. PubMed ID: 25526084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents.
    Sun D; Guo K; Rusche JJ; Hurley LH
    Nucleic Acids Res; 2005; 33(18):6070-80. PubMed ID: 16239639
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The proximal promoter region of the human vascular endothelial growth factor gene has a G-quadruplex structure that can be targeted by G-quadruplex-interactive agents.
    Sun D; Liu WJ; Guo K; Rusche JJ; Ebbinghaus S; Gokhale V; Hurley LH
    Mol Cancer Ther; 2008 Apr; 7(4):880-9. PubMed ID: 18413801
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 3'-end region of the human PDGFR-β core promoter nuclease hypersensitive element forms a mixture of two unique end-insertion G-quadruplexes.
    Onel B; Carver M; Agrawal P; Hurley LH; Yang D
    Biochim Biophys Acta Gen Subj; 2018 Apr; 1862(4):846-854. PubMed ID: 29288770
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Expression of the human telomerase reverse transcriptase gene is modulated by quadruplex formation in its first exon due to DNA methylation.
    Li PT; Wang ZF; Chu IT; Kuan YM; Li MH; Huang MC; Chiang PC; Chang TC; Chen CT
    J Biol Chem; 2017 Dec; 292(51):20859-20870. PubMed ID: 29084850
    [TBL] [Abstract][Full Text] [Related]  

  • 9. U3 region in the HIV-1 genome adopts a G-quadruplex structure in its RNA and DNA sequence.
    Piekna-Przybylska D; Sullivan MA; Sharma G; Bambara RA
    Biochemistry; 2014 Apr; 53(16):2581-93. PubMed ID: 24735378
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU).
    Meier M; Patel TR; Booy EP; Marushchak O; Okun N; Deo S; Howard R; McEleney K; Harding SE; Stetefeld J; McKenna SA
    J Biol Chem; 2013 Dec; 288(49):35014-27. PubMed ID: 24151078
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution.
    Dai J; Dexheimer TS; Chen D; Carver M; Ambrus A; Jones RA; Yang D
    J Am Chem Soc; 2006 Feb; 128(4):1096-8. PubMed ID: 16433524
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.
    Guo K; Pourpak A; Beetz-Rogers K; Gokhale V; Sun D; Hurley LH
    J Am Chem Soc; 2007 Aug; 129(33):10220-8. PubMed ID: 17672459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Coexistence of two distinct G-quadruplex conformations in the hTERT promoter.
    Lim KW; Lacroix L; Yue DJ; Lim JK; Lim JM; Phan AT
    J Am Chem Soc; 2010 Sep; 132(35):12331-42. PubMed ID: 20704263
    [TBL] [Abstract][Full Text] [Related]  

  • 14. c-MYC promoter G-quadruplex formed at the 5'-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability.
    Mathad RI; Hatzakis E; Dai J; Yang D
    Nucleic Acids Res; 2011 Nov; 39(20):9023-33. PubMed ID: 21795379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular cloning of the human platelet-derived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression.
    Qin Y; Fortin JS; Tye D; Gleason-Guzman M; Brooks TA; Hurley LH
    Biochemistry; 2010 May; 49(19):4208-19. PubMed ID: 20377208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NMR-Based model of a telomerase-inhibiting compound bound to G-quadruplex DNA.
    Fedoroff OY; Salazar M; Han H; Chemeris VV; Kerwin SM; Hurley LH
    Biochemistry; 1998 Sep; 37(36):12367-74. PubMed ID: 9730808
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4.
    Qin Y; Rezler EM; Gokhale V; Sun D; Hurley LH
    Nucleic Acids Res; 2007; 35(22):7698-713. PubMed ID: 17984069
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Epigenetic suppression of human telomerase (
    Saha D; Singh A; Hussain T; Srivastava V; Sengupta S; Kar A; Dhapola P; Dhople V; Ummanni R; Chowdhury S
    J Biol Chem; 2017 Sep; 292(37):15205-15215. PubMed ID: 28717007
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human Telomeric G-Quadruplex Structures and G-Quadruplex-Interactive Compounds.
    Lin C; Yang D
    Methods Mol Biol; 2017; 1587():171-196. PubMed ID: 28324509
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selectivity of major isoquinoline alkaloids from Chelidonium majus towards telomeric G-quadruplex: A study using a transition-FRET (t-FRET) assay.
    Noureini SK; Esmaeili H; Abachi F; Khiali S; Islam B; Kuta M; Saboury AA; Hoffmann M; Sponer J; Parkinson G; Haider S
    Biochim Biophys Acta Gen Subj; 2017 Aug; 1861(8):2020-2030. PubMed ID: 28479277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.