318 related articles for article (PubMed ID: 19602051)
1. PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease.
Morel M; Couturier J; Lafay-Chebassier C; Paccalin M; Page G
J Cell Mol Med; 2009 Aug; 13(8A):1476-88. PubMed ID: 19602051
[TBL] [Abstract][Full Text] [Related]
2. Evidence of molecular links between PKR and mTOR signalling pathways in Abeta neurotoxicity: role of p53, Redd1 and TSC2.
Morel M; Couturier J; Pontcharraud R; Gil R; Fauconneau B; Paccalin M; Page G
Neurobiol Dis; 2009 Oct; 36(1):151-61. PubMed ID: 19631745
[TBL] [Abstract][Full Text] [Related]
3. PKR, a cognitive decline biomarker, can regulate translation via two consecutive molecular targets p53 and Redd1 in lymphocytes of AD patients.
Damjanac M; Page G; Ragot S; Laborie G; Gil R; Hugon J; Paccalin M
J Cell Mol Med; 2009 Aug; 13(8B):1823-1832. PubMed ID: 19210572
[TBL] [Abstract][Full Text] [Related]
4. Activated mTOR and PKR kinases in lymphocytes correlate with memory and cognitive decline in Alzheimer's disease.
Paccalin M; Pain-Barc S; Pluchon C; Paul C; Besson MN; Carret-Rebillat AS; Rioux-Bilan A; Gil R; Hugon J
Dement Geriatr Cogn Disord; 2006; 22(4):320-6. PubMed ID: 16954686
[TBL] [Abstract][Full Text] [Related]
5. The PKR/P38/RIPK1 Signaling Pathway as a Therapeutic Target in Alzheimer's Disease.
Hugon J; Paquet C
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33808629
[TBL] [Abstract][Full Text] [Related]
6. Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity.
Suen KC; Yu MS; So KF; Chang RC; Hugon J
J Biol Chem; 2003 Dec; 278(50):49819-27. PubMed ID: 12975376
[TBL] [Abstract][Full Text] [Related]
7. PKR involvement in Alzheimer's disease.
Hugon J; Mouton-Liger F; Dumurgier J; Paquet C
Alzheimers Res Ther; 2017 Oct; 9(1):83. PubMed ID: 28982375
[TBL] [Abstract][Full Text] [Related]
8. Increased cerebrospinal fluid levels of double-stranded RNA-dependant protein kinase in Alzheimer's disease.
Mouton-Liger F; Paquet C; Dumurgier J; Lapalus P; Gray F; Laplanche JL; Hugon J;
Biol Psychiatry; 2012 May; 71(9):829-35. PubMed ID: 22281122
[TBL] [Abstract][Full Text] [Related]
9. Interaction of double-stranded RNA-dependent protein kinase (PKR) with the death receptor signaling pathway in amyloid beta (Abeta)-treated cells and in APPSLPS1 knock-in mice.
Couturier J; Morel M; Pontcharraud R; Gontier V; Fauconneau B; Paccalin M; Page G
J Biol Chem; 2010 Jan; 285(2):1272-82. PubMed ID: 19889624
[TBL] [Abstract][Full Text] [Related]
10. PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions.
Tible M; Mouton Liger F; Schmitt J; Giralt A; Farid K; Thomasseau S; Gourmaud S; Paquet C; Rondi Reig L; Meurs E; Girault JA; Hugon J
Aging Cell; 2019 Jun; 18(3):e12887. PubMed ID: 30821420
[TBL] [Abstract][Full Text] [Related]
11. Pathogenesis and promising therapeutics of Alzheimer disease through eIF2α pathway and correspondent kinases.
Moradi Majd R; Mayeli M; Rahmani F
Metab Brain Dis; 2020 Dec; 35(8):1241-1250. PubMed ID: 32681467
[TBL] [Abstract][Full Text] [Related]
12. The PKR activator PACT is induced by Aβ: involvement in Alzheimer's disease.
Paquet C; Mouton-Liger F; Meurs EF; Mazot P; Bouras C; Pradier L; Gray F; Hugon J
Brain Pathol; 2012 Mar; 22(2):219-29. PubMed ID: 21790829
[TBL] [Abstract][Full Text] [Related]
13. TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys.
Lourenco MV; Clarke JR; Frozza RL; Bomfim TR; Forny-Germano L; Batista AF; Sathler LB; Brito-Moreira J; Amaral OB; Silva CA; Freitas-Correa L; Espírito-Santo S; Campello-Costa P; Houzel JC; Klein WL; Holscher C; Carvalheira JB; Silva AM; Velloso LA; Munoz DP; Ferreira ST; De Felice FG
Cell Metab; 2013 Dec; 18(6):831-43. PubMed ID: 24315369
[TBL] [Abstract][Full Text] [Related]
14. Oxidative stress increases BACE1 protein levels through activation of the PKR-eIF2α pathway.
Mouton-Liger F; Paquet C; Dumurgier J; Bouras C; Pradier L; Gray F; Hugon J
Biochim Biophys Acta; 2012 Jun; 1822(6):885-96. PubMed ID: 22306812
[TBL] [Abstract][Full Text] [Related]
15. Activation of the cell stress kinase PKR in Alzheimer's disease and human amyloid precursor protein transgenic mice.
Peel AL; Bredesen DE
Neurobiol Dis; 2003 Oct; 14(1):52-62. PubMed ID: 13678666
[TBL] [Abstract][Full Text] [Related]
16. Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration.
Chang RC; Suen KC; Ma CH; Elyaman W; Ng HK; Hugon J
J Neurochem; 2002 Dec; 83(5):1215-25. PubMed ID: 12437593
[TBL] [Abstract][Full Text] [Related]
17. Restoring synaptic plasticity and memory in mouse models of Alzheimer's disease by PKR inhibition.
Hwang KD; Bak MS; Kim SJ; Rhee S; Lee YS
Mol Brain; 2017 Dec; 10(1):57. PubMed ID: 29233183
[TBL] [Abstract][Full Text] [Related]
18. Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy.
Guo X; Lv J; Lu J; Fan L; Huang X; Hu L; Wang J; Shen X
Neuropharmacology; 2018 Mar; 130():77-91. PubMed ID: 29197516
[TBL] [Abstract][Full Text] [Related]
19. The interferon-induced double-stranded RNA-activated protein kinase PKR will phosphorylate serine, threonine, or tyrosine at residue 51 in eukaryotic initiation factor 2alpha.
Lu J; O'Hara EB; Trieselmann BA; Romano PR; Dever TE
J Biol Chem; 1999 Nov; 274(45):32198-203. PubMed ID: 10542257
[TBL] [Abstract][Full Text] [Related]
20. The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.
Kimball SR; Clemens MJ; Tilleray VJ; Wek RC; Horetsky RL; Jefferson LS
Biochem Biophys Res Commun; 2001 Jan; 280(1):293-300. PubMed ID: 11162513
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
