232 related articles for article (PubMed ID: 19605683)
1. Cell type specificity of PI3K signaling in Pdk1- and Pten-deficient brains.
Chalhoub N; Zhu G; Zhu X; Baker SJ
Genes Dev; 2009 Jul; 23(14):1619-24. PubMed ID: 19605683
[TBL] [Abstract][Full Text] [Related]
2. Modulation in activation and expression of phosphatase and tensin homolog on chromosome ten, Akt1, and 3-phosphoinositide-dependent kinase 1: further evidence demonstrating altered phosphoinositide 3-kinase signaling in postmortem brain of suicide subjects.
Dwivedi Y; Rizavi HS; Zhang H; Roberts RC; Conley RR; Pandey GN
Biol Psychiatry; 2010 Jun; 67(11):1017-25. PubMed ID: 20163786
[TBL] [Abstract][Full Text] [Related]
3. Striking the balance between PTEN and PDK1: it all depends on the cell context.
Iwanami A; Cloughesy TF; Mischel PS
Genes Dev; 2009 Aug; 23(15):1699-704. PubMed ID: 19651981
[TBL] [Abstract][Full Text] [Related]
4. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
Rodríguez-Escudero I; Roelants FM; Thorner J; Nombela C; Molina M; Cid VJ
Biochem J; 2005 Sep; 390(Pt 2):613-23. PubMed ID: 15913452
[TBL] [Abstract][Full Text] [Related]
5. Modulation of PI3K/PTEN Pathway Does Not Affect Catalytic Activity of PDK1 in Jurkat Cells.
Yang KJ; Piao L; Shin S; Shin SY; Li Y; Lee H; Tran Q; Park J; Hong S; Brazil DP; Hemmings BA; Kim SH; Park J
Anticancer Res; 2017 Oct; 37(10):5415-5423. PubMed ID: 28982851
[TBL] [Abstract][Full Text] [Related]
6. PDK1 regulates vascular remodeling and promotes epithelial-mesenchymal transition in cardiac development.
Feng Q; Di R; Tao F; Chang Z; Lu S; Fan W; Shan C; Li X; Yang Z
Mol Cell Biol; 2010 Jul; 30(14):3711-21. PubMed ID: 20457809
[TBL] [Abstract][Full Text] [Related]
7. Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma.
Scortegagna M; Ruller C; Feng Y; Lazova R; Kluger H; Li JL; De SK; Rickert R; Pellecchia M; Bosenberg M; Ronai ZA
Oncogene; 2014 Aug; 33(34):4330-9. PubMed ID: 24037523
[TBL] [Abstract][Full Text] [Related]
8. AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
Vasudevan KM; Barbie DA; Davies MA; Rabinovsky R; McNear CJ; Kim JJ; Hennessy BT; Tseng H; Pochanard P; Kim SY; Dunn IF; Schinzel AC; Sandy P; Hoersch S; Sheng Q; Gupta PB; Boehm JS; Reiling JH; Silver S; Lu Y; Stemke-Hale K; Dutta B; Joy C; Sahin AA; Gonzalez-Angulo AM; Lluch A; Rameh LE; Jacks T; Root DE; Lander ES; Mills GB; Hahn WC; Sellers WR; Garraway LA
Cancer Cell; 2009 Jul; 16(1):21-32. PubMed ID: 19573809
[TBL] [Abstract][Full Text] [Related]
9. 3-Phosphoinositide-dependent kinase 1 potentiates upstream lesions on the phosphatidylinositol 3-kinase pathway in breast carcinoma.
Maurer M; Su T; Saal LH; Koujak S; Hopkins BD; Barkley CR; Wu J; Nandula S; Dutta B; Xie Y; Chin YR; Kim DI; Ferris JS; Gruvberger-Saal SK; Laakso M; Wang X; Memeo L; Rojtman A; Matos T; Yu JS; Cordon-Cardo C; Isola J; Terry MB; Toker A; Mills GB; Zhao JJ; Murty VV; Hibshoosh H; Parsons R
Cancer Res; 2009 Aug; 69(15):6299-306. PubMed ID: 19602588
[TBL] [Abstract][Full Text] [Related]
10. Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice.
Kilic U; Caglayan AB; Beker MC; Gunal MY; Caglayan B; Yalcin E; Kelestemur T; Gundogdu RZ; Yulug B; Yılmaz B; Kerman BE; Kilic E
Redox Biol; 2017 Aug; 12():657-665. PubMed ID: 28395173
[TBL] [Abstract][Full Text] [Related]
11. Chemotactic activation of Dictyostelium AGC-family kinases AKT and PKBR1 requires separate but coordinated functions of PDK1 and TORC2.
Liao XH; Buggey J; Kimmel AR
J Cell Sci; 2010 Mar; 123(Pt 6):983-92. PubMed ID: 20200230
[TBL] [Abstract][Full Text] [Related]
12. Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes.
Finlay DK; Sinclair LV; Feijoo C; Waugh CM; Hagenbeek TJ; Spits H; Cantrell DA
J Exp Med; 2009 Oct; 206(11):2441-54. PubMed ID: 19808258
[TBL] [Abstract][Full Text] [Related]
13. Syndecan-1-dependent suppression of PDK1/Akt/bad signaling by docosahexaenoic acid induces apoptosis in prostate cancer.
Hu Y; Sun H; Owens RT; Gu Z; Wu J; Chen YQ; O'Flaherty JT; Edwards IJ
Neoplasia; 2010 Oct; 12(10):826-36. PubMed ID: 20927321
[TBL] [Abstract][Full Text] [Related]
14. Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
Slattery ML; Lundgreen A; Herrick JS; Caan BJ; Potter JD; Wolff RK
Nutr Cancer; 2011 Nov; 63(8):1226-34. PubMed ID: 21999454
[TBL] [Abstract][Full Text] [Related]
15. Features of the reversible sensitivity-resistance transition in PI3K/PTEN/AKT signalling network after HER2 inhibition.
Goltsov A; Faratian D; Langdon SP; Mullen P; Harrison DJ; Bown J
Cell Signal; 2012 Feb; 24(2):493-504. PubMed ID: 21996585
[TBL] [Abstract][Full Text] [Related]
16. Essential role of PDK1 in regulating endothelial cell migration.
Primo L; di Blasio L; Roca C; Droetto S; Piva R; Schaffhausen B; Bussolino F
J Cell Biol; 2007 Mar; 176(7):1035-47. PubMed ID: 17371830
[TBL] [Abstract][Full Text] [Related]
17. Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.
Bayascas JR; Leslie NR; Parsons R; Fleming S; Alessi DR
Curr Biol; 2005 Oct; 15(20):1839-46. PubMed ID: 16243031
[TBL] [Abstract][Full Text] [Related]
18. IKBKE protein activates Akt independent of phosphatidylinositol 3-kinase/PDK1/mTORC2 and the pleckstrin homology domain to sustain malignant transformation.
Guo JP; Coppola D; Cheng JQ
J Biol Chem; 2011 Oct; 286(43):37389-98. PubMed ID: 21908616
[TBL] [Abstract][Full Text] [Related]
19. RET/PTC (rearranged in transformation/papillary thyroid carcinomas) tyrosine kinase phosphorylates and activates phosphoinositide-dependent kinase 1 (PDK1): an alternative phosphatidylinositol 3-kinase-independent pathway to activate PDK1.
Kim DW; Hwang JH; Suh JM; Kim H; Song JH; Hwang ES; Hwang IY; Park KC; Chung HK; Kim JM; Park J; Hemmings BA; Shong M
Mol Endocrinol; 2003 Jul; 17(7):1382-94. PubMed ID: 12738763
[TBL] [Abstract][Full Text] [Related]
20. Cardioprotective stimuli mediate phosphoinositide 3-kinase and phosphoinositide dependent kinase 1 nuclear accumulation in cardiomyocytes.
Rubio M; Avitabile D; Fischer K; Emmanuel G; Gude N; Miyamoto S; Mishra S; Schaefer EM; Brown JH; Sussman MA
J Mol Cell Cardiol; 2009 Jul; 47(1):96-103. PubMed ID: 19269295
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]