BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

165 related articles for article (PubMed ID: 19608464)

  • 1. Characterization of DNA damage-dependent cell cycle checkpoints in a menin-deficient model.
    Kottemann MC; Bale AE
    DNA Repair (Amst); 2009 Aug; 8(8):944-52. PubMed ID: 19608464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint.
    Liu H; Takeda S; Kumar R; Westergard TD; Brown EJ; Pandita TK; Cheng EH; Hsieh JJ
    Nature; 2010 Sep; 467(7313):343-6. PubMed ID: 20818375
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.
    Fang M; Xia F; Mahalingam M; Virbasius CM; Wajapeyee N; Green MR
    Mol Cell Biol; 2013 Jul; 33(13):2635-47. PubMed ID: 23648481
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ability of p53 to activate downstream genes p21(WAF1/cip1) and MDM2, and cell cycle arrest following DNA damage is delayed and attenuated in scid cells deficient in the DNA-dependent protein kinase.
    Kachnic LA; Wu B; Wunsch H; Mekeel KL; DeFrank JS; Tang W; Powell SN
    J Biol Chem; 1999 May; 274(19):13111-7. PubMed ID: 10224064
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.
    Xie G; Habbersett RC; Jia Y; Peterson SR; Lehnert BE; Bradbury EM; D'Anna JA
    Oncogene; 1998 Feb; 16(6):721-36. PubMed ID: 9488036
    [TBL] [Abstract][Full Text] [Related]  

  • 6. p53 Binding to the p21 promoter is dependent on the nature of DNA damage.
    Hill R; Bodzak E; Blough MD; Lee PW
    Cell Cycle; 2008 Aug; 7(16):2535-43. PubMed ID: 18719376
    [TBL] [Abstract][Full Text] [Related]  

  • 7. hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.
    Moumen A; Masterson P; O'Connor MJ; Jackson SP
    Cell; 2005 Dec; 123(6):1065-78. PubMed ID: 16360036
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
    Milne TA; Hughes CM; Lloyd R; Yang Z; Rozenblatt-Rosen O; Dou Y; Schnepp RW; Krankel C; Livolsi VA; Gibbs D; Hua X; Roeder RG; Meyerson M; Hess JL
    Proc Natl Acad Sci U S A; 2005 Jan; 102(3):749-54. PubMed ID: 15640349
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple endocrine neoplasia type 1 interacts with forkhead transcription factor CHES1 in DNA damage response.
    Busygina V; Kottemann MC; Scott KL; Plon SE; Bale AE
    Cancer Res; 2006 Sep; 66(17):8397-403. PubMed ID: 16951149
    [TBL] [Abstract][Full Text] [Related]  

  • 10. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB; Kislyakova TV; Aksenov ND; Osipov KA; Pospelov VA
    Oncogene; 2000 Aug; 19(34):3858-65. PubMed ID: 10951579
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Topoisomerase poisons differentially activate DNA damage checkpoints through ataxia-telangiectasia mutated-dependent and -independent mechanisms.
    Siu WY; Lau A; Arooz T; Chow JP; Ho HT; Poon RY
    Mol Cancer Ther; 2004 May; 3(5):621-32. PubMed ID: 15141020
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The p53 response to DNA damage in vivo is independent of DNA-dependent protein kinase.
    Jhappan C; Yusufzai TM; Anderson S; Anver MR; Merlino G
    Mol Cell Biol; 2000 Jun; 20(11):4075-83. PubMed ID: 10805749
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SOCS3 regulates p21 expression and cell cycle arrest in response to DNA damage.
    Sitko JC; Yeh B; Kim M; Zhou H; Takaesu G; Yoshimura A; McBride WH; Jewett A; Jamieson CA; Cacalano NA
    Cell Signal; 2008 Dec; 20(12):2221-30. PubMed ID: 18793717
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells.
    Schnepp RW; Chen YX; Wang H; Cash T; Silva A; Diehl JA; Brown E; Hua X
    Cancer Res; 2006 Jun; 66(11):5707-15. PubMed ID: 16740708
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proliferation inhibition, DNA damage, and cell-cycle arrest of human astrocytoma cells after acrylamide exposure.
    Chen JH; Tsou TC; Chiu IM; Chou CC
    Chem Res Toxicol; 2010 Sep; 23(9):1449-58. PubMed ID: 20734998
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.
    Fischer M; Quaas M; Nickel A; Engeland K
    Oncotarget; 2015 Dec; 6(39):41402-17. PubMed ID: 26595675
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ATM-dependent phosphorylation and accumulation of endogenous BLM protein in response to ionizing radiation.
    Ababou M; Dutertre S; Lécluse Y; Onclercq R; Chatton B; Amor-Guéret M
    Oncogene; 2000 Dec; 19(52):5955-63. PubMed ID: 11146546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after gamma-irradiation.
    Bulavin DV; Tararova ND; Aksenov ND; Pospelov VA; Pospelova TV
    Oncogene; 1999 Oct; 18(41):5611-9. PubMed ID: 10523840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Caffeine and human DNA metabolism: the magic and the mystery.
    Kaufmann WK; Heffernan TP; Beaulieu LM; Doherty S; Frank AR; Zhou Y; Bryant MF; Zhou T; Luche DD; Nikolaishvili-Feinberg N; Simpson DA; Cordeiro-Stone M
    Mutat Res; 2003 Nov; 532(1-2):85-102. PubMed ID: 14643431
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F; Bay JO; Dionet C; Verrelle P
    Bull Cancer; 1999 Apr; 86(4):345-57. PubMed ID: 10341340
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.