281 related articles for article (PubMed ID: 19628308)
1. Synthesis and anti-HIV activity evaluation of 2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)-N-acetamides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhan P; Liu X; Fang Z; Li Z; Pannecouque C; De Clercq E
Eur J Med Chem; 2009 Nov; 44(11):4648-53. PubMed ID: 19628308
[TBL] [Abstract][Full Text] [Related]
2. Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studies.
Zhan P; Liu X; Li Z; Fang Z; Li Z; Wang D; Pannecouque C; Clercq ED
Bioorg Med Chem; 2009 Aug; 17(16):5920-7. PubMed ID: 19620009
[TBL] [Abstract][Full Text] [Related]
3. 1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Zhan P; Liu X; Cao Y; Wang Y; Pannecouque C; De Clercq E
Bioorg Med Chem Lett; 2008 Oct; 18(20):5368-71. PubMed ID: 18824350
[TBL] [Abstract][Full Text] [Related]
4. Arylazolylthioacetanilide. Part 8: Design, synthesis and biological evaluation of novel 2-(2-(2,4-dichlorophenyl)-2H-1,2,4-triazol-3-ylthio)-N-arylacetamides as potent HIV-1 inhibitors.
Zhan P; Chen X; Li X; Li D; Tian Y; Chen W; Pannecouque C; De Clercq E; Liu X
Eur J Med Chem; 2011 Oct; 46(10):5039-45. PubMed ID: 21872971
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of novel 5-alkyl-2-arylthio-6-((3,4-dihydroquinolin-1(2H)-yl)methyl)pyrimidin-4(3H)-ones as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhang J; Zhan P; Wu J; Li Z; Jiang Y; Ge W; Pannecouque C; De Clercq E; Liu X
Bioorg Med Chem; 2011 Jul; 19(14):4366-76. PubMed ID: 21683601
[TBL] [Abstract][Full Text] [Related]
6. 1,2,3-thiadiazole thioacetanilides. Part 2: Synthesis and biological evaluation of a new series of 2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetanilides as HIV-1 inhibitors.
Zhan P; Liu XY; Li ZY; Fang ZJ; Pannecouque C; De Clercq E
Chem Biodivers; 2010 Jul; 7(7):1717-27. PubMed ID: 20658659
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Zhan P; Liu X; Zhu J; Fang Z; Li Z; Pannecouque C; Clercq ED
Bioorg Med Chem; 2009 Aug; 17(16):5775-81. PubMed ID: 19643613
[TBL] [Abstract][Full Text] [Related]
8. Nitroimidazoles. V. Synthesis and anti-HIV evaluation of new 5-substituted piperazinyl-4-nitroimidazole derivatives.
Al-Soud YA; Al-Masoudi NA; Hassan HG; De Clercq E; Pannecouque C
Acta Pharm; 2007 Dec; 57(4):379-93. PubMed ID: 18165184
[TBL] [Abstract][Full Text] [Related]
9. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological activity of naphthyl-substituted (B-ring) benzophenone derivatives as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Ma XD; Zhang X; Dai HF; Yang SQ; Yang LM; Gu SX; Zheng YT; He QQ; Chen FE
Bioorg Med Chem; 2011 Aug; 19(15):4601-7. PubMed ID: 21719299
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis, anti-HIV evaluation and molecular modeling of piperidine-linked amino-triazine derivatives as potent non-nucleoside reverse transcriptase inhibitors.
Chen X; Zhan P; Liu X; Cheng Z; Meng C; Shao S; Pannecouque C; De Clercq E; Liu X
Bioorg Med Chem; 2012 Jun; 20(12):3856-64. PubMed ID: 22591854
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, structure-activity relationships, and docking studies of N-phenylarylformamide derivatives (PAFAs) as non-nucleoside HIV reverse transcriptase inhibitors.
Ma XD; He QQ; Zhang X; Yang SQ; Yang LM; Gu SX; Zheng YT; Chen FE; Dai HF
Eur J Med Chem; 2012 Dec; 58():504-12. PubMed ID: 23164656
[TBL] [Abstract][Full Text] [Related]
13. Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses.
Tang G; Kertesz DJ; Yang M; Lin X; Wang Z; Li W; Qiu Z; Chen J; Mei J; Chen L; Mirzadegan T; Harris SF; Villaseñor AG; Fretland J; Fitch WL; Hang JQ; Heilek G; Klumpp K
Bioorg Med Chem Lett; 2010 Oct; 20(20):6020-3. PubMed ID: 20829038
[TBL] [Abstract][Full Text] [Related]
14. Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach.
Zhan P; Chen W; Li Z; Li X; Chen X; Tian Y; Pannecouque C; Clercq ED; Liu X
Bioorg Med Chem; 2012 Dec; 20(23):6795-802. PubMed ID: 23098609
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of N4-(hetero)arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors.
Xu B; Sun Y; Guo Y; Cao Y; Yu T
Bioorg Med Chem; 2009 Apr; 17(7):2767-74. PubMed ID: 19269831
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones.
Balzarini J; Orzeszko B; Maurin JK; Orzeszko A
Eur J Med Chem; 2007 Jul; 42(7):993-1003. PubMed ID: 17321639
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6-(arylcarbonyl or alpha-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors.
Ji L; Chen FE; De Clercq E; Balzarini J; Pannecouque C
J Med Chem; 2007 Apr; 50(8):1778-86. PubMed ID: 17381078
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and SAR of a novel pyrazinone series with non-nucleoside HIV-1 reverse transcriptase inhibitory activity.
Heeres J; de Jonge MR; Koymans LM; Daeyaert FF; Vinkers M; Van Aken KJ; Arnold E; Das K; Kilonda A; Hoornaert GJ; Compernolle F; Cegla M; Azzam RA; Andries K; de Béthune MP; Azijn H; Pauwels R; Lewi PJ; Janssen PA
J Med Chem; 2005 Mar; 48(6):1910-8. PubMed ID: 15771435
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, biological evaluation and molecular modeling of 4,6-diarylpyrimidines and diarylbenzenes as novel non-nucleosides HIV-1 reverse transcriptase inhibitors.
Ribone SR; Leen V; Madrid M; Dehaen W; Daelemans D; Pannecouque C; Briñón MC
Eur J Med Chem; 2012 Dec; 58():485-92. PubMed ID: 23159806
[TBL] [Abstract][Full Text] [Related]
20. Abasic analogues of TSAO-T as the first sugar derivatives that specifically inhibit HIV-1 reverse transcriptase.
Velázquez S; Chamorro C; Pérez-Pérez MJ; Alvarez R; Jimeno ML; Martín-Domenech A; Pérez C; Gago F; De Clercq E; Balzarini J; San-Félix A; Camarasa MJ
J Med Chem; 1998 Nov; 41(23):4636-47. PubMed ID: 9804703
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
