418 related articles for article (PubMed ID: 19628752)
1. Construction of triple-transfected cells [organic anion-transporting polypeptide (OATP) 1B1/multidrug resistance-associated protein (MRP) 2/MRP3 and OATP1B1/MRP2/MRP4] for analysis of the sinusoidal function of MRP3 and MRP4.
Hirouchi M; Kusuhara H; Onuki R; Ogilvie BW; Parkinson A; Sugiyama Y
Drug Metab Dispos; 2009 Oct; 37(10):2103-11. PubMed ID: 19628752
[TBL] [Abstract][Full Text] [Related]
2. Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor.
Yamada A; Maeda K; Kamiyama E; Sugiyama D; Kondo T; Shiroyanagi Y; Nakazawa H; Okano T; Adachi M; Schuetz JD; Adachi Y; Hu Z; Kusuhara H; Sugiyama Y
Drug Metab Dispos; 2007 Dec; 35(12):2166-76. PubMed ID: 17823233
[TBL] [Abstract][Full Text] [Related]
3. Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.
Matsushima S; Maeda K; Kondo C; Hirano M; Sasaki M; Suzuki H; Sugiyama Y
J Pharmacol Exp Ther; 2005 Sep; 314(3):1059-67. PubMed ID: 15901800
[TBL] [Abstract][Full Text] [Related]
4. Involvement of transporters in the hepatic uptake and biliary excretion of valsartan, a selective antagonist of the angiotensin II AT1-receptor, in humans.
Yamashiro W; Maeda K; Hirouchi M; Adachi Y; Hu Z; Sugiyama Y
Drug Metab Dispos; 2006 Jul; 34(7):1247-54. PubMed ID: 16624871
[TBL] [Abstract][Full Text] [Related]
5. Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.
Järvinen E; Troberg J; Kidron H; Finel M
Mol Pharm; 2017 Oct; 14(10):3299-3311. PubMed ID: 28850245
[TBL] [Abstract][Full Text] [Related]
6. Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.
Ishiguro N; Maeda K; Saito A; Kishimoto W; Matsushima S; Ebner T; Roth W; Igarashi T; Sugiyama Y
Drug Metab Dispos; 2008 Apr; 36(4):796-805. PubMed ID: 18180273
[TBL] [Abstract][Full Text] [Related]
7. The roles of MRP2, MRP3, OATP1B1, and OATP1B3 in conjugated hyperbilirubinemia.
Keppler D
Drug Metab Dispos; 2014 Apr; 42(4):561-5. PubMed ID: 24459177
[TBL] [Abstract][Full Text] [Related]
8. Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport.
Yamazaki M; Li B; Louie SW; Pudvah NT; Stocco R; Wong W; Abramovitz M; Demartis A; Laufer R; Hochman JH; Prueksaritanont T; Lin JH
Xenobiotica; 2005 Jul; 35(7):737-53. PubMed ID: 16316932
[TBL] [Abstract][Full Text] [Related]
9. Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice.
Zamek-Gliszczynski MJ; Nezasa K; Tian X; Bridges AS; Lee K; Belinsky MG; Kruh GD; Brouwer KL
J Pharmacol Exp Ther; 2006 Dec; 319(3):1485-91. PubMed ID: 16988054
[TBL] [Abstract][Full Text] [Related]
10. Hepatic Disposition of Gemfibrozil and Its Major Metabolite Gemfibrozil 1-O-β-Glucuronide.
Kimoto E; Li R; Scialis RJ; Lai Y; Varma MV
Mol Pharm; 2015 Nov; 12(11):3943-52. PubMed ID: 26378985
[TBL] [Abstract][Full Text] [Related]
11. Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).
Hirohashi T; Suzuki H; Sugiyama Y
J Biol Chem; 1999 May; 274(21):15181-5. PubMed ID: 10329726
[TBL] [Abstract][Full Text] [Related]
12. Identification of the transporters involved in the hepatobiliary transport and intestinal efflux of methyl 1-(3,4-dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) glucuronide, a pharmacologically active metabolite of S-8921.
Sakamoto S; Kusuhara H; Horie K; Takahashi K; Baba T; Ishizaki J; Sugiyama Y
Drug Metab Dispos; 2008 Aug; 36(8):1553-61. PubMed ID: 18474677
[TBL] [Abstract][Full Text] [Related]
13. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
Noé J; Portmann R; Brun ME; Funk C
Drug Metab Dispos; 2007 Aug; 35(8):1308-14. PubMed ID: 17470528
[TBL] [Abstract][Full Text] [Related]
14. Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis.
Keitel V; Burdelski M; Warskulat U; Kühlkamp T; Keppler D; Häussinger D; Kubitz R
Hepatology; 2005 May; 41(5):1160-72. PubMed ID: 15841457
[TBL] [Abstract][Full Text] [Related]
15. Evaluation of the role of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in the urinary excretion of sulfate and glucuronide metabolites of edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one).
Mizuno N; Takahashi T; Kusuhara H; Schuetz JD; Niwa T; Sugiyama Y
Drug Metab Dispos; 2007 Nov; 35(11):2045-52. PubMed ID: 17682070
[TBL] [Abstract][Full Text] [Related]
16. Hepatocellular organic anion-transporting polypeptides (OATPs) and multidrug resistance-associated protein 2 (MRP2) are inhibited by silibinin.
Wlcek K; Koller F; Ferenci P; Stieger B
Drug Metab Dispos; 2013 Aug; 41(8):1522-8. PubMed ID: 23695864
[TBL] [Abstract][Full Text] [Related]
17. Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs.
Ieiri I; Higuchi S; Sugiyama Y
Expert Opin Drug Metab Toxicol; 2009 Jul; 5(7):703-29. PubMed ID: 19442037
[TBL] [Abstract][Full Text] [Related]
18. Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.
Gui C; Miao Y; Thompson L; Wahlgren B; Mock M; Stieger B; Hagenbuch B
Eur J Pharmacol; 2008 Apr; 584(1):57-65. PubMed ID: 18321482
[TBL] [Abstract][Full Text] [Related]
19. Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells.
Fahrmayr C; König J; Auge D; Mieth M; Fromm MF
Br J Pharmacol; 2012 Mar; 165(6):1836-1847. PubMed ID: 21923755
[TBL] [Abstract][Full Text] [Related]
20. The eighth and ninth transmembrane domains in organic anion transporting polypeptide 1B1 affect the transport kinetics of estrone-3-sulfate and estradiol-17beta-D-glucuronide.
Miyagawa M; Maeda K; Aoyama A; Sugiyama Y
J Pharmacol Exp Ther; 2009 May; 329(2):551-7. PubMed ID: 19244099
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]