BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

643 related articles for article (PubMed ID: 19629035)

  • 1. PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.
    Bryant HE; Petermann E; Schultz N; Jemth AS; Loseva O; Issaeva N; Johansson F; Fernandez S; McGlynn P; Helleday T
    EMBO J; 2009 Sep; 28(17):2601-15. PubMed ID: 19629035
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA-PKcs and PARP1 Bind to Unresected Stalled DNA Replication Forks Where They Recruit XRCC1 to Mediate Repair.
    Ying S; Chen Z; Medhurst AL; Neal JA; Bao Z; Mortusewicz O; McGouran J; Song X; Shen H; Hamdy FC; Kessler BM; Meek K; Helleday T
    Cancer Res; 2016 Mar; 76(5):1078-88. PubMed ID: 26603896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mre11-dependent degradation of stalled DNA replication forks is prevented by BRCA2 and PARP1.
    Ying S; Hamdy FC; Helleday T
    Cancer Res; 2012 Jun; 72(11):2814-21. PubMed ID: 22447567
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation.
    Ronson GE; Piberger AL; Higgs MR; Olsen AL; Stewart GS; McHugh PJ; Petermann E; Lakin ND
    Nat Commun; 2018 Feb; 9(1):746. PubMed ID: 29467415
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.
    Petermann E; Orta ML; Issaeva N; Schultz N; Helleday T
    Mol Cell; 2010 Feb; 37(4):492-502. PubMed ID: 20188668
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair.
    Bryant HE; Helleday T
    Nucleic Acids Res; 2006; 34(6):1685-91. PubMed ID: 16556909
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3.
    Richards F; Llorca-Cardenosa MJ; Langton J; Buch-Larsen SC; Shamkhi NF; Sharma AB; Nielsen ML; Lakin ND
    Nat Commun; 2023 Jul; 14(1):4310. PubMed ID: 37463936
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Replication fork stability confers chemoresistance in BRCA-deficient cells.
    Ray Chaudhuri A; Callen E; Ding X; Gogola E; Duarte AA; Lee JE; Wong N; Lafarga V; Calvo JA; Panzarino NJ; John S; Day A; Crespo AV; Shen B; Starnes LM; de Ruiter JR; Daniel JA; Konstantinopoulos PA; Cortez D; Cantor SB; Fernandez-Capetillo O; Ge K; Jonkers J; Rottenberg S; Sharan SK; Nussenzweig A
    Nature; 2016 Jul; 535(7612):382-7. PubMed ID: 27443740
    [TBL] [Abstract][Full Text] [Related]  

  • 9. APLF facilitates interstrand DNA crosslink repair and replication fork protection to confer cisplatin resistance.
    Wu CK; Shiu JL; Wu CL; Hung CF; Ho YC; Chen YT; Tung SY; Yeh CF; Shen CH; Liaw H; Su WP
    Nucleic Acids Res; 2024 Jun; 52(10):5676-5697. PubMed ID: 38520407
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks.
    Yang YG; Cortes U; Patnaik S; Jasin M; Wang ZQ
    Oncogene; 2004 May; 23(21):3872-82. PubMed ID: 15021907
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ZNF365 promotes stalled replication forks recovery to maintain genome stability.
    Zhang Y; Park E; Kim CS; Paik JH
    Cell Cycle; 2013 Sep; 12(17):2817-28. PubMed ID: 23966166
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart.
    Somyajit K; Saxena S; Babu S; Mishra A; Nagaraju G
    Nucleic Acids Res; 2015 Nov; 43(20):9835-55. PubMed ID: 26354865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The oncoprotein DEK affects the outcome of PARP1/2 inhibition during mild replication stress.
    Ganz M; Vogel C; Czada C; Jörke V; Gwosch EC; Kleiner R; Pierzynska-Mach A; Zanacchi FC; Diaspro A; Kappes F; Bürkle A; Ferrando-May E
    PLoS One; 2019; 14(8):e0213130. PubMed ID: 31408463
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic Evidence for Roles of Yeast Mitotic Cyclins at Single-Stranded Gaps Created by DNA Replication.
    Signon L
    G3 (Bethesda); 2018 Feb; 8(2):737-752. PubMed ID: 29279302
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities.
    Torres JZ; Schnakenberg SL; Zakian VA
    Mol Cell Biol; 2004 Apr; 24(8):3198-212. PubMed ID: 15060144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Poly(ADP-ribose) polymerase (PARP-1) in homologous recombination and as a target for cancer therapy.
    Helleday T; Bryant HE; Schultz N
    Cell Cycle; 2005 Sep; 4(9):1176-8. PubMed ID: 16123586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human single-stranded DNA binding protein 1 (hSSB1/NABP2) is required for the stability and repair of stalled replication forks.
    Bolderson E; Petermann E; Croft L; Suraweera A; Pandita RK; Pandita TK; Helleday T; Khanna KK; Richard DJ
    Nucleic Acids Res; 2014 Jun; 42(10):6326-36. PubMed ID: 24753408
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks.
    Trenz K; Smith E; Smith S; Costanzo V
    EMBO J; 2006 Apr; 25(8):1764-74. PubMed ID: 16601701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.
    Robison JG; Elliott J; Dixon K; Oakley GG
    J Biol Chem; 2004 Aug; 279(33):34802-10. PubMed ID: 15180989
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.
    Ewald B; Sampath D; Plunkett W
    Cancer Res; 2008 Oct; 68(19):7947-55. PubMed ID: 18829552
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 33.