116 related articles for article (PubMed ID: 19632112)
1. Inhibitors of HIV-1 attachment. Part 3: A preliminary survey of the effect of structural variation of the benzamide moiety on antiviral activity.
Meanwell NA; Wallace OB; Wang H; Deshpande M; Pearce BC; Trehan A; Yeung KS; Qiu Z; Wright JJ; Robinson BA; Gong YF; Wang HG; Spicer TP; Blair WS; Shi PY; Lin PF
Bioorg Med Chem Lett; 2009 Sep; 19(17):5136-9. PubMed ID: 19632112
[TBL] [Abstract][Full Text] [Related]
2. Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives.
Wang T; Kadow JF; Zhang Z; Yin Z; Gao Q; Wu D; Parker DD; Yang Z; Zadjura L; Robinson BA; Gong YF; Spicer TP; Blair WS; Shi PY; Yamanaka G; Lin PF; Meanwell NA
Bioorg Med Chem Lett; 2009 Sep; 19(17):5140-5. PubMed ID: 19664921
[TBL] [Abstract][Full Text] [Related]
3. Inhibitors of HIV-1 attachment. Part 2: An initial survey of indole substitution patterns.
Meanwell NA; Wallace OB; Fang H; Wang H; Deshpande M; Wang T; Yin Z; Zhang Z; Pearce BC; James J; Yeung KS; Qiu Z; Kim Wright JJ; Yang Z; Zadjura L; Tweedie DL; Yeola S; Zhao F; Ranadive S; Robinson BA; Gong YF; Wang HG; Spicer TP; Blair WS; Shi PY; Colonno RJ; Lin PF
Bioorg Med Chem Lett; 2009 Apr; 19(7):1977-81. PubMed ID: 19251416
[TBL] [Abstract][Full Text] [Related]
4. Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 5. An evolution from indole to azaindoles leading to the discovery of 1-(4-benzoylpiperazin-1-yl)-2-(4,7-dimethoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-488043), a drug candidate that demonstrates antiviral activity in HIV-1-infected subjects.
Wang T; Yin Z; Zhang Z; Bender JA; Yang Z; Johnson G; Yang Z; Zadjura LM; D'Arienzo CJ; DiGiugno Parker D; Gesenberg C; Yamanaka GA; Gong YF; Ho HT; Fang H; Zhou N; McAuliffe BV; Eggers BJ; Fan L; Nowicka-Sans B; Dicker IB; Gao Q; Colonno RJ; Lin PF; Meanwell NA; Kadow JF
J Med Chem; 2009 Dec; 52(23):7778-87. PubMed ID: 19769332
[TBL] [Abstract][Full Text] [Related]
5. Inhibitors of HIV-1 attachment: The discovery and structure-activity relationships of tetrahydroisoquinolines as replacements for the piperazine benzamide in the 3-glyoxylyl 6-azaindole pharmacophore.
Swidorski JJ; Liu Z; Yin Z; Wang T; Carini DJ; Rahematpura S; Zheng M; Johnson K; Zhang S; Lin PF; Parker DD; Li W; Meanwell NA; Hamann LG; Regueiro-Ren A
Bioorg Med Chem Lett; 2016 Jan; 26(1):160-7. PubMed ID: 26584882
[TBL] [Abstract][Full Text] [Related]
6. CD4 mimics targeting the mechanism of HIV entry.
Yamada Y; Ochiai C; Yoshimura K; Tanaka T; Ohashi N; Narumi T; Nomura W; Harada S; Matsushita S; Tamamura H
Bioorg Med Chem Lett; 2010 Jan; 20(1):354-8. PubMed ID: 19926478
[TBL] [Abstract][Full Text] [Related]
7. Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction.
Williams DH; Adam F; Fenwick DR; Fok-Seang J; Gardner I; Hay D; Jaiessh R; Middleton DS; Mowbray CE; Parkinson T; Perros M; Pickford C; Platts M; Randall A; Siddle D; Stephenson PT; Tran TD; Vuong H
Bioorg Med Chem Lett; 2009 Sep; 19(17):5246-9. PubMed ID: 19620004
[TBL] [Abstract][Full Text] [Related]
8. Heterobiaryl human immunodeficiency virus entry inhibitors.
Lu RJ; Tucker JA; Pickens J; Ma YA; Zinevitch T; Kirichenko O; Konoplev V; Kuznetsova S; Sviridov S; Brahmachary E; Khasanov A; Mikel C; Yang Y; Liu C; Wang J; Freel S; Fisher S; Sullivan A; Zhou J; Stanfield-Oakley S; Baker B; Sailstad J; Greenberg M; Bolognesi D; Bray B; Koszalka B; Jeffs P; Jeffries C; Chucholowski A; Sexton C
J Med Chem; 2009 Jul; 52(14):4481-7. PubMed ID: 19534463
[TBL] [Abstract][Full Text] [Related]
9. Inhibitors of human immunodeficiency virus type 1 (HIV-1) attachment. 12. Structure-activity relationships associated with 4-fluoro-6-azaindole derivatives leading to the identification of 1-(4-benzoylpiperazin-1-yl)-2-(4-fluoro-7-[1,2,3]triazol-1-yl-1h-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (BMS-585248).
Regueiro-Ren A; Xue QM; Swidorski JJ; Gong YF; Mathew M; Parker DD; Yang Z; Eggers B; D'Arienzo C; Sun Y; Malinowski J; Gao Q; Wu D; Langley DR; Colonno RJ; Chien C; Grasela DM; Zheng M; Lin PF; Meanwell NA; Kadow JF
J Med Chem; 2013 Feb; 56(4):1656-69. PubMed ID: 23360431
[TBL] [Abstract][Full Text] [Related]
10. Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions.
Wang T; Zhang Z; Wallace OB; Deshpande M; Fang H; Yang Z; Zadjura LM; Tweedie DL; Huang S; Zhao F; Ranadive S; Robinson BS; Gong YF; Ricarrdi K; Spicer TP; Deminie C; Rose R; Wang HG; Blair WS; Shi PY; Lin PF; Colonno RJ; Meanwell NA
J Med Chem; 2003 Sep; 46(20):4236-9. PubMed ID: 13678401
[TBL] [Abstract][Full Text] [Related]
11. Non-peptide entry inhibitors of HIV-1 that target the gp41 coiled coil pocket.
Stewart KD; Huth JR; Ng TI; McDaniel K; Hutchinson RN; Stoll VS; Mendoza RR; Matayoshi ED; Carrick R; Mo H; Severin J; Walter K; Richardson PL; Barrett LW; Meadows R; Anderson S; Kohlbrenner W; Maring C; Kempf DJ; Molla A; Olejniczak ET
Bioorg Med Chem Lett; 2010 Jan; 20(2):612-7. PubMed ID: 20004576
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and evaluation of potential inhibitors of HIV gp120-CD4 interactions.
Boussard C; Klimkait T; Mahmood N; Pritchard M; Gilbert IH
Bioorg Med Chem Lett; 2004 May; 14(10):2673-6. PubMed ID: 15109676
[TBL] [Abstract][Full Text] [Related]
13. Design and optimisation of potent gp120-CD4 inhibitors.
Tran TD; Adam FM; Calo F; Fenwick DR; Fok-Seang J; Gardner I; Hay DA; Perros M; Rawal J; Middleton DS; Parkinson T; Pickford C; Platts M; Randall A; Stephenson PT; Vuong H; Williams DH
Bioorg Med Chem Lett; 2009 Sep; 19(17):5250-5. PubMed ID: 19632839
[TBL] [Abstract][Full Text] [Related]
14. Docking and 3D-QSAR studies of BMS-806 analogs as HIV-1 gp120 entry inhibitors.
Teixeira C; Serradji N; Maurel F; Barbault F
Eur J Med Chem; 2009 Sep; 44(9):3524-32. PubMed ID: 19410340
[TBL] [Abstract][Full Text] [Related]
15. Inhibitors of HIV-1 attachment. Part 10. The discovery and structure-activity relationships of 4-azaindole cores.
Wang T; Yang Z; Zhang Z; Gong YF; Riccardi KA; Lin PF; Parker DD; Rahematpura S; Mathew M; Zheng M; Meanwell NA; Kadow JF; Bender JA
Bioorg Med Chem Lett; 2013 Jan; 23(1):213-7. PubMed ID: 23200254
[TBL] [Abstract][Full Text] [Related]
16. Novel hexahydropyrrolo[3,4-c]pyrrole CCR5 antagonists.
Rotstein DM; Melville CR; Padilla F; Cournoyer D; Lee EK; Lemoine R; Petersen AC; Setti LQ; Wanner J; Chen L; Filonova L; Loughhead DG; Manka J; Lin XF; Gleason S; Sankuratri S; Ji C; Derosier A; Dioszegi M; Heilek G; Jekle A; Berry P; Mau CI; Weller P
Bioorg Med Chem Lett; 2010 May; 20(10):3116-9. PubMed ID: 20417098
[TBL] [Abstract][Full Text] [Related]
17. A survey of core replacements in indole-based HIV-1 attachment inhibitors.
Wang T; Wallace OB; Zhang Z; Fang H; Yang Z; Robinson BA; Spicer TP; Gong YF; Blair WS; Shi PY; Lin PF; Deshpande M; Meanwell NA; Kadow JF
Bioorg Med Chem Lett; 2019 Jun; 29(11):1423-1429. PubMed ID: 30940396
[TBL] [Abstract][Full Text] [Related]
18. Inhibitors of HIV-1 attachment. Part 8: the effect of C7-heteroaryl substitution on the potency, and in vitro and in vivo profiles of indole-based inhibitors.
Yeung KS; Qiu Z; Yin Z; Trehan A; Fang H; Pearce B; Yang Z; Zadjura L; D'Arienzo CJ; Riccardi K; Shi PY; Spicer TP; Gong YF; Browning MR; Hansel S; Santone K; Barker J; Coulter T; Lin PF; Meanwell NA; Kadow JF
Bioorg Med Chem Lett; 2013 Jan; 23(1):203-8. PubMed ID: 23200249
[TBL] [Abstract][Full Text] [Related]
19. Linear and non-linear quantitative structure-activity relationship models on indole substitution patterns as inhibitors of HIV-1 attachment.
Nirouei M; Ghasemi G; Abdolmaleki P; Tavakoli A; Shariati S
Indian J Biochem Biophys; 2012 Jun; 49(3):202-10. PubMed ID: 22803336
[TBL] [Abstract][Full Text] [Related]
20. HIV protease inhibitory bis-benzamide cyclic ureas: a quantitative structure-activity relationship analysis.
Wilkerson WW; Akamike E; Cheatham WW; Hollis AY; Collins RD; DeLucca I; Lam PY; Ru Y
J Med Chem; 1996 Oct; 39(21):4299-312. PubMed ID: 8863807
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
