BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 19636513)

  • 1. The induction of senescence-like growth arrest by protein kinase C-activating diterpene esters in solid tumor cells.
    Mason SA; Cozzi SJ; Pierce CJ; Pavey SJ; Parsons PG; Boyle GM
    Invest New Drugs; 2010 Oct; 28(5):575-86. PubMed ID: 19636513
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway.
    Cozzi SJ; Parsons PG; Ogbourne SM; Pedley J; Boyle GM
    Cancer Res; 2006 Oct; 66(20):10083-91. PubMed ID: 17047072
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells.
    Frey MR; Clark JA; Bateman NW; Kazanietz MG; Black AR; Black JD
    Biochem Pharmacol; 2004 May; 67(10):1873-86. PubMed ID: 15130764
    [TBL] [Abstract][Full Text] [Related]  

  • 4. S-Phase-specific activation of PKC alpha induces senescence in non-small cell lung cancer cells.
    Oliva JL; Caino MC; Senderowicz AM; Kazanietz MG
    J Biol Chem; 2008 Feb; 283(9):5466-76. PubMed ID: 18162471
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of the cell cycle at the G2/M boundary in metastatic melanoma cells by 12-O-tetradecanoyl phorbol-13-acetate (TPA) by blocking p34cdc2 kinase activity.
    Arita Y; Buffolino P; Coppock DL
    Exp Cell Res; 1998 Aug; 242(2):381-90. PubMed ID: 9683525
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phorbol esters induce death in MCF-7 breast cancer cells with altered expression of protein kinase C isoforms. Role for p53-independent induction of gadd-45 in initiating death.
    de Vente JE; Kukoly CA; Bryant WO; Posekany KJ; Chen J; Fletcher DJ; Parker PJ; Pettit GJ; Lozano G; Cook PP
    J Clin Invest; 1995 Oct; 96(4):1874-86. PubMed ID: 7560079
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells.
    Frey MR; Saxon ML; Zhao X; Rollins A; Evans SS; Black JD
    J Biol Chem; 1997 Apr; 272(14):9424-35. PubMed ID: 9083081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of both extracellular signal-regulated kinase and c-jun N-terminal kinase pathways in the 12-O-tetradecanoylphorbol-13-acetate-induced upregulation of p21(Cip1) in colon cancer cells.
    Lin SY; Liang YC; Ho YS; Tsai SH; Pan S; Lee WS
    Mol Carcinog; 2002 Sep; 35(1):21-8. PubMed ID: 12203364
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells.
    Benhadji KA; Serova M; Ghoul A; Cvitkovic E; Le Tourneau C; Ogbourne SM; Lokiec F; Calvo F; Hammel P; Faivre S; Raymond E
    Br J Cancer; 2008 Dec; 99(11):1808-15. PubMed ID: 19034280
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Growth of human melanocyte cultures supported by 12-O-tetradecanoylphorbol-13-acetate is mediated through protein kinase C activation.
    Arita Y; O'Driscoll KR; Weinstein IB
    Cancer Res; 1992 Aug; 52(16):4514-21. PubMed ID: 1643643
    [TBL] [Abstract][Full Text] [Related]  

  • 11. On the mechanisms of 12-O-tetradecanoylphorbol-13-acetate-induced growth arrest in pancreatic cancer cells.
    Salabat MR; Ding XZ; Flesche JB; Ujiki MB; Robin TP; Talamonti MS; Bell RH; Adrian TE
    Pancreas; 2006 Aug; 33(2):148-55. PubMed ID: 16868480
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activated Ki-Ras suppresses 12-O-tetradecanoylphorbol-13-acetate-induced activation of the c-Jun NH2-terminal kinase pathway in human colon cancer cells.
    Okumura K; Shirasawa S; Nishioka M; Sasazuki T
    Cancer Res; 1999 May; 59(10):2445-50. PubMed ID: 10344756
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulations of Reversal of Senescence by PKC Isozymes in Response to 12-O-Tetradecanoylphorbol-13-Acetate via Nuclear Translocation of pErk1/2.
    Lee YY; Ryu MS; Kim HS; Suganuma M; Song KY; Lim IK
    Mol Cells; 2016 Mar; 39(3):266-79. PubMed ID: 26912086
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ectopic expression of protein kinase C-β sensitizes head and neck squamous cell carcinoma to diterpene esters.
    Adams RA; D'Souza MM; Pierce CJ; Korica N; Wallwork B; Parsons PG; Panizza B; Boyle GM
    Anticancer Res; 2015 Mar; 35(3):1291-6. PubMed ID: 25750277
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of p21(Waf1/Cip1) in protein kinase C alpha-induced cell cycle progression.
    Besson A; Yong VW
    Mol Cell Biol; 2000 Jul; 20(13):4580-90. PubMed ID: 10848585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Upregulation of p21(WAF1/CIP1) leads to morphologic changes and esterase activity in TPA-mediated differentiation of human prostate cancer cell line TSU-Pr1.
    Sugibayashi R; Shimizu T; Suzuki T; Yamamoto N; Hamada H; Takeda K
    Oncogene; 2001 Mar; 20(10):1220-8. PubMed ID: 11313866
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKC pathway and ERK/MAPK pathway are required for induction of cyclin D1 and p21Waf1 during 12-o-tetradecanoylphorbol 13-acetate-induced differentiation of myeloleukemia cells.
    Matsumoto E; Hatanaka M; Bohgaki M; Maeda S
    Kobe J Med Sci; 2006; 52(6):181-94. PubMed ID: 17329956
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mitogen-activated protein kinase pathway mediates growth arrest or E1A-dependent apoptosis in SKBR3 human breast cancer cells.
    Blagosklonny MV
    Int J Cancer; 1998 Nov; 78(4):511-7. PubMed ID: 9797142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta.
    Gill PK; Gescher A; Gant TW
    Eur J Biochem; 2001 Aug; 268(15):4151-7. PubMed ID: 11488907
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of conventional mammalian protein kinase C isoforms expressed in budding yeast modulates the cell doubling time--a potential in vivo screen for protein kinase C activators.
    Shieh HL; Hansen H; Zhu J; Riedel H
    Cancer Detect Prev; 1996; 20(6):576-89. PubMed ID: 8939343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.