216 related articles for article (PubMed ID: 19637923)
1. Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation.
Kowol CR; Trondl R; Heffeter P; Arion VB; Jakupec MA; Roller A; Galanski MS; Berger W; Keppler BK
J Med Chem; 2009 Aug; 52(16):5032-43. PubMed ID: 19637923
[TBL] [Abstract][Full Text] [Related]
2. Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.
Popović-Bijelić A; Kowol CR; Lind ME; Luo J; Himo F; Enyedy EA; Arion VB; Gräslund A
J Inorg Biochem; 2011 Nov; 105(11):1422-31. PubMed ID: 21955844
[TBL] [Abstract][Full Text] [Related]
3. Gallium(III) and iron(III) complexes of alpha-N-heterocyclic thiosemicarbazones: synthesis, characterization, cytotoxicity, and interaction with ribonucleotide reductase.
Kowol CR; Berger R; Eichinger R; Roller A; Jakupec MA; Schmidt PP; Arion VB; Keppler BK
J Med Chem; 2007 Mar; 50(6):1254-65. PubMed ID: 17315858
[TBL] [Abstract][Full Text] [Related]
4. Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells.
Ohui K; Stepanenko I; Besleaga I; Babak MV; Stafi R; Darvasiova D; Giester G; Pósa V; Enyedy EA; Vegh D; Rapta P; Ang WH; Popović-Bijelić A; Arion VB
Biomolecules; 2020 Sep; 10(9):. PubMed ID: 32961653
[TBL] [Abstract][Full Text] [Related]
5. Novel thiosemicarbazones of the ApT and DpT series and their copper complexes: identification of pronounced redox activity and characterization of their antitumor activity.
Jansson PJ; Sharpe PC; Bernhardt PV; Richardson DR
J Med Chem; 2010 Aug; 53(15):5759-69. PubMed ID: 20597487
[TBL] [Abstract][Full Text] [Related]
6. Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes: Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity.
Stepanenko I; Babak MV; Spengler G; Hammerstad M; Popovic-Bijelic A; Shova S; Büchel GE; Darvasiova D; Rapta P; Arion VB
Biomolecules; 2021 Jun; 11(6):. PubMed ID: 34207929
[TBL] [Abstract][Full Text] [Related]
7. 2-Acetylpyridine thiosemicarbazones are potent iron chelators and antiproliferative agents: redox activity, iron complexation and characterization of their antitumor activity.
Richardson DR; Kalinowski DS; Richardson V; Sharpe PC; Lovejoy DB; Islam M; Bernhardt PV
J Med Chem; 2009 Mar; 52(5):1459-70. PubMed ID: 19216562
[TBL] [Abstract][Full Text] [Related]
8. Alkyl substituted 2'-benzoylpyridine thiosemicarbazone chelators with potent and selective anti-neoplastic activity: novel ligands that limit methemoglobin formation.
Stefani C; Jansson PJ; Gutierrez E; Bernhardt PV; Richardson DR; Kalinowski DS
J Med Chem; 2013 Jan; 56(1):357-70. PubMed ID: 23276209
[TBL] [Abstract][Full Text] [Related]
9. Synthesis, crystal structure and antiproliferative mechanisms of 2-acetylpyridine-thiosemicarbazones Ga(III) with a greater selectivity against tumor cells.
Qi J; Zheng Y; Qian K; Tian L; Zhang GX; Cheng Z; Wang Y
J Inorg Biochem; 2017 Dec; 177():110-117. PubMed ID: 28946027
[TBL] [Abstract][Full Text] [Related]
10. Iron-targeting antitumor activity of gallium compounds and novel insights into triapine(®)-metal complexes.
Chitambar CR; Antholine WE
Antioxid Redox Signal; 2013 Mar; 18(8):956-72. PubMed ID: 22900955
[TBL] [Abstract][Full Text] [Related]
11. Halogenated 2'-benzoylpyridine thiosemicarbazone (XBpT) chelators with potent and selective anti-neoplastic activity: relationship to intracellular redox activity.
Stefani C; Punnia-Moorthy G; Lovejoy DB; Jansson PJ; Kalinowski DS; Sharpe PC; Bernhardt PV; Richardson DR
J Med Chem; 2011 Oct; 54(19):6936-48. PubMed ID: 21846118
[TBL] [Abstract][Full Text] [Related]
12. Complex formation and cytotoxicity of Triapine derivatives: a comparative solution study on the effect of the chalcogen atom and NH-methylation.
Enyedy ÉA; May NV; Pape VFS; Heffeter P; Szakács G; Keppler BK; Kowol CR
Dalton Trans; 2020 Dec; 49(46):16887-16902. PubMed ID: 33185224
[TBL] [Abstract][Full Text] [Related]
13. Activity and electrochemical properties: iron complexes of the anticancer drug triapine and its analogs.
Plamthottam S; Sun D; Van Valkenburgh J; Valenzuela J; Ruehle B; Steele D; Poddar S; Marshalik M; Hernandez S; Radu CG; Zink JI
J Biol Inorg Chem; 2019 Aug; 24(5):621-632. PubMed ID: 31250199
[TBL] [Abstract][Full Text] [Related]
14. Triapine Analogues and Their Copper(II) Complexes: Synthesis, Characterization, Solution Speciation, Redox Activity, Cytotoxicity, and mR2 RNR Inhibition.
Besleaga I; Stepanenko I; Petrasheuskaya TV; Darvasiova D; Breza M; Hammerstad M; Marć MA; Prado-Roller A; Spengler G; Popović-Bijelić A; Enyedy EA; Rapta P; Shutalev AD; Arion VB
Inorg Chem; 2021 Aug; 60(15):11297-11319. PubMed ID: 34279079
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, Characterization, and in Vitro Anticancer Activity of Copper and Zinc Bis(Thiosemicarbazone) Complexes.
Anjum R; Palanimuthu D; Kalinowski DS; Lewis W; Park KC; Kovacevic Z; Khan IU; Richardson DR
Inorg Chem; 2019 Oct; 58(20):13709-13723. PubMed ID: 31339305
[TBL] [Abstract][Full Text] [Related]
16. Novel 2-pyridinecarboxaldehyde thiosemicarbazones Ga(III) complexes with a high antiproliferative activity by promoting apoptosis and inhibiting cell cycle.
Qi J; Deng J; Qian K; Tian L; Li J; He K; Huang X; Cheng Z; Zheng Y; Wang Y
Eur J Med Chem; 2017 Jul; 134():34-42. PubMed ID: 28395152
[TBL] [Abstract][Full Text] [Related]
17. Metal complexes of 3-(4-bromophenyl)-1-pyridin-2-ylprop-2-en-1-one thiosemicarbazone: cytotoxic activity and investigation on the mode of action of the gold(III) complex.
Sâmia LB; Parrilha GL; Da Silva JG; Ramos JP; Souza-Fagundes EM; Castelli S; Vutey V; Desideri A; Beraldo H
Biometals; 2016 Jun; 29(3):515-26. PubMed ID: 27091443
[TBL] [Abstract][Full Text] [Related]
18. Kinetico-mechanistic studies on methemoglobin generation by biologically active thiosemicarbazone iron(III) complexes.
Basha MT; Bordini J; Richardson DR; Martinez M; Bernhardt PV
J Inorg Biochem; 2016 Sep; 162():326-333. PubMed ID: 27079328
[TBL] [Abstract][Full Text] [Related]
19. New Iminodiacetate-Thiosemicarbazone Hybrids and Their Copper(II) Complexes Are Potential Ribonucleotide Reductase R2 Inhibitors with High Antiproliferative Activity.
Zaltariov MF; Hammerstad M; Arabshahi HJ; Jovanović K; Richter KW; Cazacu M; Shova S; Balan M; Andersen NH; Radulović S; Reynisson J; Andersson KK; Arion VB
Inorg Chem; 2017 Mar; 56(6):3532-3549. PubMed ID: 28252952
[TBL] [Abstract][Full Text] [Related]
20. Design, synthesis, and characterization of novel iron chelators: structure-activity relationships of the 2-benzoylpyridine thiosemicarbazone series and their 3-nitrobenzoyl analogues as potent antitumor agents.
Kalinowski DS; Yu Y; Sharpe PC; Islam M; Liao YT; Lovejoy DB; Kumar N; Bernhardt PV; Richardson DR
J Med Chem; 2007 Jul; 50(15):3716-29. PubMed ID: 17602603
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
