372 related articles for article (PubMed ID: 19642642)
1. Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime.
Sanson B; Nachon F; Colletier JP; Froment MT; Toker L; Greenblatt HM; Sussman JL; Ashani Y; Masson P; Silman I; Weik M
J Med Chem; 2009 Dec; 52(23):7593-603. PubMed ID: 19642642
[TBL] [Abstract][Full Text] [Related]
2. Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.
Millard CB; Kryger G; Ordentlich A; Greenblatt HM; Harel M; Raves ML; Segall Y; Barak D; Shafferman A; Silman I; Sussman JL
Biochemistry; 1999 Jun; 38(22):7032-9. PubMed ID: 10353814
[TBL] [Abstract][Full Text] [Related]
3. Structural changes of phenylalanine 338 and histidine 447 revealed by the crystal structures of tabun-inhibited murine acetylcholinesterase.
Ekström F; Akfur C; Tunemalm AK; Lundberg S
Biochemistry; 2006 Jan; 45(1):74-81. PubMed ID: 16388582
[TBL] [Abstract][Full Text] [Related]
4. Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging.
Nachon F; Asojo OA; Borgstahl GE; Masson P; Lockridge O
Biochemistry; 2005 Feb; 44(4):1154-62. PubMed ID: 15667209
[TBL] [Abstract][Full Text] [Related]
5. Exploring the active center of human acetylcholinesterase with stereomers of an organophosphorus inhibitor with two chiral centers.
Ordentlich A; Barak D; Kronman C; Benschop HP; De Jong LP; Ariel N; Barak R; Segall Y; Velan B; Shafferman A
Biochemistry; 1999 Mar; 38(10):3055-66. PubMed ID: 10074358
[TBL] [Abstract][Full Text] [Related]
6. The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism.
Saxena A; Viragh C; Frazier DS; Kovach IM; Maxwell DM; Lockridge O; Doctor BP
Biochemistry; 1998 Oct; 37(43):15086-96. PubMed ID: 9790671
[TBL] [Abstract][Full Text] [Related]
7. Efficacy of structural homoloques and isomers of pralidoxime in reactivation of immobilised acetylcholinesterase inhibited with sarin, cyclosarin and soman.
Hoskovcova M; Halamek E; Kobliha Z
Neuro Endocrinol Lett; 2009; 30 Suppl 1():152-5. PubMed ID: 20027163
[TBL] [Abstract][Full Text] [Related]
8. Phosphoryl oxime inhibition of acetylcholinesterase during oxime reactivation is prevented by edrophonium.
Luo C; Saxena A; Smith M; Garcia G; Radić Z; Taylor P; Doctor BP
Biochemistry; 1999 Aug; 38(31):9937-47. PubMed ID: 10433700
[TBL] [Abstract][Full Text] [Related]
9. Unique push-pull mechanism of dealkylation in soman-inhibited cholinesterases.
Viragh C; Akhmetshin R; Kovach IM; Broomfield C
Biochemistry; 1997 Jul; 36(27):8243-52. PubMed ID: 9204869
[TBL] [Abstract][Full Text] [Related]
10. Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation.
Carletti E; Li H; Li B; Ekström F; Nicolet Y; Loiodice M; Gillon E; Froment MT; Lockridge O; Schopfer LM; Masson P; Nachon F
J Am Chem Soc; 2008 Nov; 130(47):16011-20. PubMed ID: 18975951
[TBL] [Abstract][Full Text] [Related]
11. Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis.
Aurbek N; Thiermann H; Eyer F; Eyer P; Worek F
Toxicology; 2009 May; 259(3):133-9. PubMed ID: 19428953
[TBL] [Abstract][Full Text] [Related]
12. Aging-resistant organophosphate bioscavenger based on polyethylene glycol-conjugated F338A human acetylcholinesterase.
Mazor O; Cohen O; Kronman C; Raveh L; Stein D; Ordentlich A; Shafferman A
Mol Pharmacol; 2008 Sep; 74(3):755-63. PubMed ID: 18523134
[TBL] [Abstract][Full Text] [Related]
13. Direct observation and elucidation of the structures of aged and nonaged phosphorylated cholinesterases by 31P NMR spectroscopy.
Segall Y; Waysbort D; Barak D; Ariel N; Doctor BP; Grunwald J; Ashani Y
Biochemistry; 1993 Dec; 32(49):13441-50. PubMed ID: 8257680
[TBL] [Abstract][Full Text] [Related]
14. Crystal structures of brain group-VIII phospholipase A2 in nonaged complexes with the organophosphorus nerve agents soman and sarin.
Epstein TM; Samanta U; Kirby SD; Cerasoli DM; Bahnson BJ
Biochemistry; 2009 Apr; 48(15):3425-35. PubMed ID: 19271773
[TBL] [Abstract][Full Text] [Related]
15. The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design.
Greenblatt HM; Guillou C; Guénard D; Argaman A; Botti S; Badet B; Thal C; Silman I; Sussman JL
J Am Chem Soc; 2004 Dec; 126(47):15405-11. PubMed ID: 15563167
[TBL] [Abstract][Full Text] [Related]
16. Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning.
Saxena A; Maxwell DM; Quinn DM; Radić Z; Taylor P; Doctor BP
Biochem Pharmacol; 1997 Jul; 54(2):269-74. PubMed ID: 9271331
[TBL] [Abstract][Full Text] [Related]
17. Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819).
Bartolucci C; Siotto M; Ghidini E; Amari G; Bolzoni PT; Racchi M; Villetti G; Delcanale M; Lamba D
J Med Chem; 2006 Aug; 49(17):5051-8. PubMed ID: 16913695
[TBL] [Abstract][Full Text] [Related]
18. Structural approach to the aging of phosphylated cholinesterases.
Masson P; Nachon F; Lockridge O
Chem Biol Interact; 2010 Sep; 187(1-3):157-62. PubMed ID: 20338153
[TBL] [Abstract][Full Text] [Related]
19. The role of glutamate-199 in the aging of cholinesterase.
Saxena A; Doctor BP; Maxwell DM; Lenz DE; Radic Z; Taylor P
Biochem Biophys Res Commun; 1993 Nov; 197(1):343-9. PubMed ID: 7902714
[TBL] [Abstract][Full Text] [Related]
20. Disentangling the formation, mechanism, and evolvement of the covalent methanesulfonyl fluoride acetylcholinesterase adduct: Insights into an aged-like inactive complex susceptible to reactivation by a combination of nucleophiles.
Stojan J; Pesaresi A; Meden A; Lamba D
Protein Sci; 2024 May; 33(5):e4977. PubMed ID: 38591646
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
