BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1576 related articles for article (PubMed ID: 19644473)

  • 1. Targeting the phosphoinositide 3-kinase pathway in cancer.
    Liu P; Cheng H; Roberts TM; Zhao JJ
    Nat Rev Drug Discov; 2009 Aug; 8(8):627-44. PubMed ID: 19644473
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PI3K and cancer: lessons, challenges and opportunities.
    Fruman DA; Rommel C
    Nat Rev Drug Discov; 2014 Feb; 13(2):140-56. PubMed ID: 24481312
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting the PI3K/Akt/mTOR pathway in malignancy: rationale and clinical outlook.
    Cho DC
    BioDrugs; 2014 Aug; 28(4):373-81. PubMed ID: 24567265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of PI3K inhibitors: lessons learned from early clinical trials.
    Rodon J; Dienstmann R; Serra V; Tabernero J
    Nat Rev Clin Oncol; 2013 Mar; 10(3):143-53. PubMed ID: 23400000
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the PI3-kinase/Akt/mTOR signaling pathway.
    Hassan B; Akcakanat A; Holder AM; Meric-Bernstam F
    Surg Oncol Clin N Am; 2013 Oct; 22(4):641-64. PubMed ID: 24012393
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of the PI3K/AKT/mTOR Pathway in Solid Tumors.
    LoRusso PM
    J Clin Oncol; 2016 Nov; 34(31):3803-3815. PubMed ID: 27621407
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PI3K/Akt/mTOR pathway inhibitors in cancer: a perspective on clinical progress.
    Wu P; Hu YZ
    Curr Med Chem; 2010; 17(35):4326-41. PubMed ID: 20939811
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Current Status and Future Role of the Phosphoinositide 3 Kinase/AKT Signaling Pathway in Urothelial Cancer: An Old Pathway in the New Immunotherapy Era.
    Liu ST; Hui G; Mathis C; Chamie K; Pantuck AJ; Drakaki A
    Clin Genitourin Cancer; 2018 Apr; 16(2):e269-e276. PubMed ID: 29199023
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PI3K/Akt/mTOR inhibitors in cancer: At the bench and bedside.
    Alzahrani AS
    Semin Cancer Biol; 2019 Dec; 59():125-132. PubMed ID: 31323288
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway.
    Polivka J; Janku F
    Pharmacol Ther; 2014 May; 142(2):164-75. PubMed ID: 24333502
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Involvement of PI3K/Akt pathway in prostate cancer--potential strategies for developing targeted therapies.
    Pommery N; Hénichart JP
    Mini Rev Med Chem; 2005 Dec; 5(12):1125-32. PubMed ID: 16375758
    [TBL] [Abstract][Full Text] [Related]  

  • 12. mTOR pathway inhibitors in cancer therapy: moving past rapamycin.
    Wacheck V
    Pharmacogenomics; 2010 Sep; 11(9):1189-91. PubMed ID: 20860456
    [No Abstract]   [Full Text] [Related]  

  • 13. Targeting PI3K in cancer: mechanisms and advances in clinical trials.
    Yang J; Nie J; Ma X; Wei Y; Peng Y; Wei X
    Mol Cancer; 2019 Feb; 18(1):26. PubMed ID: 30782187
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations.
    LoPiccolo J; Blumenthal GM; Bernstein WB; Dennis PA
    Drug Resist Updat; 2008; 11(1-2):32-50. PubMed ID: 18166498
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI3K/Akt/mTOR signaling in medullary thyroid cancer: a promising molecular target for cancer therapy.
    Manfredi GI; Dicitore A; Gaudenzi G; Caraglia M; Persani L; Vitale G
    Endocrine; 2015 Mar; 48(2):363-70. PubMed ID: 25115638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New inhibitors of the mammalian target of rapamycin signaling pathway for cancer.
    Albert S; Serova M; Dreyer C; Sablin MP; Faivre S; Raymond E
    Expert Opin Investig Drugs; 2010 Aug; 19(8):919-30. PubMed ID: 20569080
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis.
    Newton HB
    Expert Rev Anticancer Ther; 2004 Feb; 4(1):105-28. PubMed ID: 14748662
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting the PI3K/Akt/mTOR pathway for breast cancer therapy.
    Cidado J; Park BH
    J Mammary Gland Biol Neoplasia; 2012 Dec; 17(3-4):205-16. PubMed ID: 22865098
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises.
    Yap TA; Garrett MD; Walton MI; Raynaud F; de Bono JS; Workman P
    Curr Opin Pharmacol; 2008 Aug; 8(4):393-412. PubMed ID: 18721898
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
    Gao N; Flynn DC; Zhang Z; Zhong XS; Walker V; Liu KJ; Shi X; Jiang BH
    Am J Physiol Cell Physiol; 2004 Aug; 287(2):C281-91. PubMed ID: 15028555
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 79.