These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 1964460)

  • 21. Aspartic acid 349 in the fourth epidermal growth factor-like structure of human thrombomodulin plays a role in its Ca(2+)-mediated binding to protein C.
    Zushi M; Gomi K; Honda G; Kondo S; Yamamoto S; Hayashi T; Suzuki K
    J Biol Chem; 1991 Oct; 266(30):19886-9. PubMed ID: 1657904
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Alanine-scanning mutagenesis of the epidermal growth factor-like domains of human thrombomodulin identifies critical residues for its cofactor activity.
    Nagashima M; Lundh E; Leonard JC; Morser J; Parkinson JF
    J Biol Chem; 1993 Feb; 268(4):2888-92. PubMed ID: 8381415
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.
    Stearns-Kurosawa DJ; Kurosawa S; Mollica JS; Ferrell GL; Esmon CT
    Proc Natl Acad Sci U S A; 1996 Sep; 93(19):10212-6. PubMed ID: 8816778
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Properties of a recombinant chimeric protein in which the gamma-carboxyglutamic acid and helical stack domains of human anticoagulant protein C are replaced by those of human coagulation factor VII.
    Geng JP; Castellino FJ
    Thromb Haemost; 1997 May; 77(5):926-33. PubMed ID: 9184404
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Thrombomodulin changes the molecular surface of interaction and the rate of complex formation between thrombin and protein C.
    Xu H; Bush LA; Pineda AO; Caccia S; Di Cera E
    J Biol Chem; 2005 Mar; 280(9):7956-61. PubMed ID: 15582990
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Activation of protein C by the thrombin-thrombomodulin complex: cooperative roles of Arg-35 of thrombin and Arg-67 of protein C.
    Yang L; Manithody C; Rezaie AR
    Proc Natl Acad Sci U S A; 2006 Jan; 103(4):879-84. PubMed ID: 16418283
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The active site of thrombin is altered upon binding to thrombomodulin. Two distinct structural changes are detected by fluorescence, but only one correlates with protein C activation.
    Ye J; Esmon NL; Esmon CT; Johnson AE
    J Biol Chem; 1991 Dec; 266(34):23016-21. PubMed ID: 1660464
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Identification of a thrombin-binding region in the sixth epidermal growth factor-like repeat of human thrombomodulin.
    Tolkatchev D; Ng A; Zhu B; Ni F
    Biochemistry; 2000 Aug; 39(34):10365-72. PubMed ID: 10956026
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Equilibrium binding of thrombin to recombinant human thrombomodulin: effect of hirudin, fibrinogen, factor Va, and peptide analogues.
    Tsiang M; Lentz SR; Dittman WA; Wen D; Scarpati EM; Sadler JE
    Biochemistry; 1990 Nov; 29(47):10602-12. PubMed ID: 2176873
    [TBL] [Abstract][Full Text] [Related]  

  • 30. One-step sandwich enzyme immunoassay for soluble human thrombomodulin using monoclonal antibodies.
    Kodama S; Uchijima E; Nagai M; Mikawatani K; Hayashi T; Suzuki K
    Clin Chim Acta; 1990 Dec; 192(3):191-9. PubMed ID: 1962742
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The interaction of thrombomodulin with Ca2+.
    Light DR; Glaser CB; Betts M; Blasko E; Campbell E; Clarke JH; McCaman M; McLean K; Nagashima M; Parkinson JF; Rumennik G; Young T; Morser J
    Eur J Biochem; 1999 Jun; 262(2):522-33. PubMed ID: 10336638
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The role of complex formation and epidermal growth factor-like domains in the regulation of blood coagulation by the thrombomodulin-protein C system.
    Kurosawa S
    Nihon Ketsueki Gakkai Zasshi; 1989 Dec; 52(8):1343-9. PubMed ID: 2560886
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A domain composed of epidermal growth factor-like structures of human thrombomodulin is essential for thrombin binding and for protein C activation.
    Suzuki K; Hayashi T; Nishioka J; Kosaka Y; Zushi M; Honda G; Yamamoto S
    J Biol Chem; 1989 Mar; 264(9):4872-6. PubMed ID: 2538465
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Energetics of thrombin-thrombomodulin interaction.
    Vindigni A; White CE; Komives EA; Di Cera E
    Biochemistry; 1997 Jun; 36(22):6674-81. PubMed ID: 9184147
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.
    Koeppe JR; Beach MA; Baerga-Ortiz A; Kerns SJ; Komives EA
    Biochemistry; 2008 Oct; 47(41):10933-9. PubMed ID: 18803401
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Exosite 2-Directed Ligands Attenuate Protein C Activation by the Thrombin-Thrombomodulin Complex.
    Chen K; Stafford AR; Wu C; Yeh CH; Kim PY; Fredenburgh JC; Weitz JI
    Biochemistry; 2017 Jun; 56(24):3119-3128. PubMed ID: 28549218
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The Gla26 residue of protein C is required for the binding of protein C to thrombomodulin and endothelial cell protein C receptor, but not to protein S and factor Va.
    Nishioka J; Ido M; Hayashi T; Suzuki K
    Thromb Haemost; 1996 Feb; 75(2):275-82. PubMed ID: 8815576
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity.
    Zushi M; Gomi K; Yamamoto S; Maruyama I; Hayashi T; Suzuki K
    J Biol Chem; 1989 Jun; 264(18):10351-3. PubMed ID: 2543666
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Thrombomodulin Binding Selects the Catalytically Active Form of Thrombin.
    Handley LD; Treuheit NA; Venkatesh VJ; Komives EA
    Biochemistry; 2015 Nov; 54(43):6650-8. PubMed ID: 26468766
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structure-function studies of the epidermal growth factor domains of human thrombomodulin.
    Parkinson JF; Nagashima M; Kuhn I; Leonard J; Morser J
    Biochem Biophys Res Commun; 1992 Jun; 185(2):567-76. PubMed ID: 1319140
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.