135 related articles for article (PubMed ID: 19647430)
21. Synthesis and activity of a new class of dual acting norepinephrine and serotonin reuptake inhibitors: 3-(1H-indol-1-yl)-3-arylpropan-1-amines.
Mahaney PE; Vu AT; McComas CC; Zhang P; Nogle LM; Watts WL; Sarkahian A; Leventhal L; Sullivan NR; Uveges AJ; Trybulski EJ
Bioorg Med Chem; 2006 Dec; 14(24):8455-66. PubMed ID: 16973367
[TBL] [Abstract][Full Text] [Related]
22. 4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.
Pechulis AD; Beck JP; Curry MA; Wolf MA; Harms AE; Xi N; Opalka C; Sweet MP; Yang Z; Vellekoop AS; Klos AM; Crocker PJ; Hassler C; Laws M; Kitchen DB; Smith MA; Olson RE; Liu S; Molino BF
Bioorg Med Chem Lett; 2012 Dec; 22(23):7219-22. PubMed ID: 23084899
[TBL] [Abstract][Full Text] [Related]
23. Design and synthesis of promiscuous high-affinity monoamine transporter ligands: unraveling transporter selectivity.
Greiner E; Boos TL; Prisinzano TE; De Martino MG; Zeglis B; Dersch CM; Marcus J; Partilla JS; Rothman RB; Jacobson AE; Rice KC
J Med Chem; 2006 Mar; 49(5):1766-72. PubMed ID: 16509591
[TBL] [Abstract][Full Text] [Related]
24. A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: synthesis and structure-activity relationships.
Van Orden LJ; Van Dyke PM; Saito DR; Church TJ; Chang R; Smith JA; Martin WJ; Jaw-Tsai S; Stangeland EL
Bioorg Med Chem Lett; 2013 Mar; 23(5):1456-61. PubMed ID: 23347683
[TBL] [Abstract][Full Text] [Related]
25. Design and optimisation of selective serotonin re-uptake inhibitors with high synthetic accessibility: part 2.
Andrews M; Brown A; Chiva JY; Fradet D; Gordon D; Lansdell M; MacKenny M
Bioorg Med Chem Lett; 2009 Oct; 19(20):5893-7. PubMed ID: 19740658
[TBL] [Abstract][Full Text] [Related]
26. Discovery and structure-activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors.
Boot J; Cases M; Clark BP; Findlay J; Gallagher PT; Hayhurst L; Man T; Montalbetti C; Rathmell RE; Rudyk H; Walter MW; Whatton M; Wood V
Bioorg Med Chem Lett; 2005 Feb; 15(3):699-703. PubMed ID: 15664840
[TBL] [Abstract][Full Text] [Related]
27. Discovery of a new series of monoamine reuptake inhibitors, the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ols.
Kim CY; Mahaney PE; McConnell O; Zhang Y; Manas E; Ho DM; Deecher DC; Trybulski EJ
Bioorg Med Chem Lett; 2009 Sep; 19(17):5029-32. PubMed ID: 19632110
[TBL] [Abstract][Full Text] [Related]
28. Design, synthesis, and pharmacological evaluation of azetedine and pyrrolidine derivatives as dual norepinephrine reuptake inhibitors and 5-HT(1A) partial agonists.
Pettersson M; Campbell BM; Dounay AB; Gray DL; Xie L; O'Donnell CJ; Stratman NC; Zoski K; Drummond E; Bora G; Probert A; Whisman T
Bioorg Med Chem Lett; 2011 Jan; 21(2):865-8. PubMed ID: 21185183
[TBL] [Abstract][Full Text] [Related]
29. [4-(Phenoxy)pyridin-3-yl]methylamines: a new class of selective noradrenaline reuptake inhibitors.
Fish PV; Ryckmans T; Stobie A; Wakenhut F
Bioorg Med Chem Lett; 2008 Mar; 18(6):1795-8. PubMed ID: 18313294
[TBL] [Abstract][Full Text] [Related]
30. Pyrrolidin-3-yl-N-methylbenzamides as potent histamine 3 receptor antagonists.
Zhou D; Gross JL; Sze JY; Adedoyin AB; Bowlby M; Di L; Platt BJ; Zhang G; Brandon N; Comery TA; Robichaud AJ
Bioorg Med Chem Lett; 2011 Oct; 21(19):5957-60. PubMed ID: 21843941
[TBL] [Abstract][Full Text] [Related]
31. Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters.
Dutta AK; Santra S; Sharma H; Voshavar C; Xu L; Mabrouk O; Antonio T; Reith ME
PLoS One; 2014; 9(11):e113420. PubMed ID: 25427177
[TBL] [Abstract][Full Text] [Related]
32. Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
Orjales A; Mosquera R; Toledo A; Pumar MC; García N; Cortizo L; Labeaga L; Innerárity A
J Med Chem; 2003 Dec; 46(25):5512-32. PubMed ID: 14640559
[TBL] [Abstract][Full Text] [Related]
33. Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition.
Fish PV; Deur C; Gan X; Greene K; Hoople D; Mackenny M; Para KS; Reeves K; Ryckmans T; Stiff C; Stobie A; Wakenhut F; Whitlock GA
Bioorg Med Chem Lett; 2008 Apr; 18(8):2562-6. PubMed ID: 18387300
[TBL] [Abstract][Full Text] [Related]
34. Benzothienyloxy phenylpropanamines, novel dual inhibitors of serotonin and norepinephrine reuptake.
Boot JR; Brace G; Delatour CL; Dezutter N; Fairhurst J; Findlay J; Gallagher PT; Hoes I; Mahadevan S; Mitchell SN; Rathmell RE; Richards SJ; Simmonds RG; Wallace L; Whatton MA
Bioorg Med Chem Lett; 2004 Nov; 14(21):5395-9. PubMed ID: 15454233
[TBL] [Abstract][Full Text] [Related]
35. Synthesis of new 4-butyl-arylpiperazine-3-(1H-indol-3-yl)pyrrolidine-2,5-dione derivatives and evaluation for their 5-HT
Wróbel MZ; Chodkowski A; Marciniak M; Dawidowski M; Maksymiuk A; Siwek A; Nowak G; Turło J
Bioorg Chem; 2020 Apr; 97():103662. PubMed ID: 32086055
[TBL] [Abstract][Full Text] [Related]
36. Structure-activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril cores.
Fensome A; Goldberg J; McComas CC; Trybulski EJ; Woodworth RP; Deecher DC; Whiteside GT; Zhang P
Bioorg Med Chem Lett; 2010 Mar; 20(5):1555-8. PubMed ID: 20153188
[TBL] [Abstract][Full Text] [Related]
37. 3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors.
Vu AT; Cohn ST; Terefenko EA; Moore WJ; Zhang P; Mahaney PE; Trybulski EJ; Goljer I; Dooley R; Bray JA; Johnston GH; Leiter J; Deecher DC
Bioorg Med Chem Lett; 2009 May; 19(9):2464-7. PubMed ID: 19329313
[TBL] [Abstract][Full Text] [Related]
38. Further studies on conformationally constrained tricyclic tropane analogues and their uptake inhibition at monoamine transporter sites: synthesis of (Z)-9-(substituted arylmethylene)-7-azatricyclo[4.3.1.0(3,7)]decanes as a novel class of serotonin transporter inhibitors.
Zhang A; Zhou G; Hoepping A; Mukhopadhyaya J; Johnson KM; Zhang M; Kozikowski AP
J Med Chem; 2002 Apr; 45(9):1930-41. PubMed ID: 11960503
[TBL] [Abstract][Full Text] [Related]
39. Synthesis and evaluation of dopamine and serotonin transporter inhibition by oxacyclic and carbacyclic analogues of methylphenidate.
Meltzer PC; Wang P; Blundell P; Madras BK
J Med Chem; 2003 Apr; 46(8):1538-45. PubMed ID: 12672255
[TBL] [Abstract][Full Text] [Related]
40. The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes.
Purushotham M; Sheri A; Pham-Huu DP; Madras BK; Janowsky A; Meltzer PC
Bioorg Med Chem Lett; 2011 Jan; 21(1):48-51. PubMed ID: 21146984
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
