BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

360 related articles for article (PubMed ID: 19647933)

  • 1. XN05, a novel synthesized microtubule inhibitor, exhibits potent activity against human carcinoma cells in vitro.
    Wu R; Ding W; Liu T; Zhu H; Hu Y; Yang B; He Q
    Cancer Lett; 2009 Nov; 285(1):13-22. PubMed ID: 19647933
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
    Liou JP; Hsu KS; Kuo CC; Chang CY; Chang JY
    J Pharmacol Exp Ther; 2007 Oct; 323(1):398-405. PubMed ID: 17660383
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
    Chang JY; Chang CY; Kuo CC; Chen LT; Wein YS; Kuo YH
    Mol Pharmacol; 2004 Jan; 65(1):77-84. PubMed ID: 14722239
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Double blockade of cell cycle at g(1)-s transition and m phase by 3-iodoacetamido benzoyl ethyl ester, a new type of tubulin ligand.
    Jiang JD; Denner L; Ling YH; Li JN; Davis A; Wang Y; Li Y; Roboz J; Wang LG; Perez-Soler R; Marcelli M; Bekesi G; Holland JF
    Cancer Res; 2002 Nov; 62(21):6080-8. PubMed ID: 12414632
    [TBL] [Abstract][Full Text] [Related]  

  • 5. BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo.
    Kuo CC; Hsieh HP; Pan WY; Chen CP; Liou JP; Lee SJ; Chang YL; Chen LT; Chen CT; Chang JY
    Cancer Res; 2004 Jul; 64(13):4621-8. PubMed ID: 15231674
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK; Han EK; Credo B; Jae HS; Pietenpol JA; Scatena CD; Wu-Wong JR; Frost D; Sham H; Rosenberg SH; Ng SC
    Cancer Res; 2001 Jul; 61(14):5480-5. PubMed ID: 11454695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytotoxic activity and cytostatic mechanism of novel 2-arylbenzo[b]furans.
    Yang H; Pang JY; Cai YC; Xu ZL; Xian LJ
    J Pharm Pharmacol; 2006 Sep; 58(9):1281-7. PubMed ID: 16945188
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
    Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3-(Iodoacetamido)-benzoylurea: a novel cancericidal tubulin ligand that inhibits microtubule polymerization, phosphorylates bcl-2, and induces apoptosis in tumor cells.
    Jiang JD; Davis AS; Middleton K; Ling YH; Perez-Soler R; Holland JF; Bekesi JG
    Cancer Res; 1998 Dec; 58(23):5389-95. PubMed ID: 9850070
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glucocorticoid protects hepatoma cells against metabolic stress-induced cell death.
    Uen YH; Ko PH; Yin PH; Liu TY; Chi CW; Lui WY
    Int J Oncol; 2008 Dec; 33(6):1263-70. PubMed ID: 19020760
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DAT-230, a novel microtubule inhibitor, exhibits potent anti-tumor activity by inducing G2/M phase arrest, apoptosis in vitro and perfusion decrease in vivo to HT-1080.
    Qiao F; Zuo D; Shen X; Qi H; Wang H; Zhang W; Wu Y
    Cancer Chemother Pharmacol; 2012 Aug; 70(2):259-70. PubMed ID: 22752214
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
    Wong VK; Chiu P; Chung SS; Chow LM; Zhao YZ; Yang BB; Ko BC
    Clin Cancer Res; 2005 Aug; 11(16):6002-11. PubMed ID: 16115945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of apoptosis by HAC-Y6, a novel microtubule inhibitor, through activation of the death receptor 4 signaling pathway in human hepatocellular carcinoma cells.
    Tsai JY; Hung CM; Bai ST; Huang CH; Chen WC; Chung JG; Kuo SC; Way TD; Huang LJ
    Oncol Rep; 2010 Nov; 24(5):1169-78. PubMed ID: 20878107
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z; Zhou Z; Tian W; Fan X; Xue D; Yu L; Yu Q; Long YQ
    ChemMedChem; 2012 Apr; 7(4):680-93. PubMed ID: 22311585
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, formulation and in vitro evaluation of a novel microtubule destabilizer, SMART-100.
    Li F; Lu Y; Li W; Miller DD; Mahato RI
    J Control Release; 2010 Apr; 143(1):151-8. PubMed ID: 20060430
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Adenovirus vector expressing mda-7 selectively kills hepatocellular carcinoma cell line Hep3B.
    Xue XB; Chen K; Wang CJ; Zheng JW; Yu Y; Peng ZH; Wu ZD
    Hepatobiliary Pancreat Dis Int; 2008 Oct; 7(5):509-14. PubMed ID: 18842498
    [TBL] [Abstract][Full Text] [Related]  

  • 17. KRIBB3, a novel microtubule inhibitor, induces mitotic arrest and apoptosis in human cancer cells.
    Shin KD; Yoon YJ; Kang YR; Son KH; Kim HM; Kwon BM; Han DC
    Biochem Pharmacol; 2008 Jan; 75(2):383-94. PubMed ID: 17915194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Inhibitory effect of the venom of spider Macrothele raveni on proliferation of human hepatocellular carcinoma cell line BEL-7402 and its mechanism].
    Gao L; Feng W; Shan BE; Zhu BC
    Ai Zheng; 2005 Jul; 24(7):812-6. PubMed ID: 16004806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The synthetic compound CC-5079 is a potent inhibitor of tubulin polymerization and tumor necrosis factor-alpha production with antitumor activity.
    Zhang LH; Wu L; Raymon HK; Chen RS; Corral L; Shirley MA; Narla RK; Gamez J; Muller GW; Stirling DI; Bartlett JB; Schafer PH; Payvandi F
    Cancer Res; 2006 Jan; 66(2):951-9. PubMed ID: 16424030
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones and benzylidene-9(10H)-anthracenones as novel tubulin interacting agents with high apoptosis-inducing activity.
    Zuse A; Prinz H; Müller K; Schmidt P; Günther EG; Schweizer F; Prehn JH; Los M
    Eur J Pharmacol; 2007 Dec; 575(1-3):34-45. PubMed ID: 17707367
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.