114 related articles for article (PubMed ID: 19652407)
1. Synthesis and biological evaluation of a new set of pyrazolo[1,5-c]quinazolines as glycine/N-methyl-D-aspartic acid receptor antagonists.
Varano F; Catarzi D; Colotta V; Poli D; Filacchioni G; Galli A; Costagli C
Chem Pharm Bull (Tokyo); 2009 Aug; 57(8):826-9. PubMed ID: 19652407
[TBL] [Abstract][Full Text] [Related]
2. 1-Substituted pyrazolo[1,5-c]quinazolines as novel Gly/NMDA receptor antagonists: synthesis, biological evaluation, and molecular modeling study.
Varano F; Catarzi D; Colotta V; Calabri FR; Lenzi O; Filacchioni G; Galli A; Costagli C; Deflorian F; Moro S
Bioorg Med Chem; 2005 Oct; 13(19):5536-49. PubMed ID: 16087341
[TBL] [Abstract][Full Text] [Related]
3. Novel AMPA and kainate receptor antagonists containing the pyrazolo[1,5-c]quinazoline ring system: Synthesis and structure-activity relationships.
Varano F; Catarzi D; Colotta V; Lenzi O; Filacchioni G; Galli A; Costagli C
Bioorg Med Chem; 2008 Mar; 16(5):2617-26. PubMed ID: 18063372
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of a new set of pyrazolo[1,5-c]quinazoline-2-carboxylates as novel excitatory amino acid antagonists.
Varano F; Catarzi D; Colotta V; Filacchioni G; Galli A; Costagli C; Carlà V
J Med Chem; 2002 Feb; 45(5):1035-44. PubMed ID: 11855983
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological evaluation of novel 9-heteroaryl substituted 7-chloro-4,5-dihydro-4-oxo-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylates (TQX) as (R,S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA) receptor antagonists.
Catarzi D; Colotta V; Varano F; Filacchioni G; Gratteri P; Sgrignani J; Galli A; Costagli C
Chem Pharm Bull (Tokyo); 2008 Aug; 56(8):1085-91. PubMed ID: 18670107
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and biological evaluation of analogues of 7-chloro-4,5-dihydro-4- oxo-8-(1,2,4-triazol-4-yl)-1,2,4-triazolo[1,5-a]quinoxaline-2-carboxylic acid (TQX-173) as novel selective AMPA receptor antagonists.
Catarzi D; Colotta V; Varano F; Calabri FR; Filacchioni G; Galli A; Costagli C; Carlà V
J Med Chem; 2004 Jan; 47(1):262-72. PubMed ID: 14695840
[TBL] [Abstract][Full Text] [Related]
7. 3-hydroxy-quinazoline-2,4-dione as a useful scaffold to obtain selective Gly/NMDA and AMPA receptor antagonists.
Colotta V; Catarzi D; Varano F; Calabri FR; Filacchioni G; Costagli C; Galli A
Bioorg Med Chem Lett; 2004 May; 14(9):2345-9. PubMed ID: 15081038
[TBL] [Abstract][Full Text] [Related]
8. 4,5-Dihydro-1,2,4-triazolo[1,5-a]quinoxalin-4-ones: excitatory amino acid antagonists with combined glycine/NMDA and AMPA receptor affinity.
Catarzi D; Colotta V; Varano F; Cecchi L; Filacchioni G; Galli A; Costagli C
J Med Chem; 1999 Jul; 42(13):2478-84. PubMed ID: 10395489
[TBL] [Abstract][Full Text] [Related]
9. Pyrazolo[1,5-c]quinazoline derivatives and their simplified analogues as adenosine receptor antagonists: synthesis, structure-affinity relationships and molecular modeling studies.
Catarzi D; Colotta V; Varano F; Poli D; Squarcialupi L; Filacchioni G; Varani K; Vincenzi F; Borea PA; Dal Ben D; Lambertucci C; Cristalli G
Bioorg Med Chem; 2013 Jan; 21(1):283-94. PubMed ID: 23171656
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and pharmacological studies at the Gly/NMDA, AMPA and Kainate receptors of new oxazolo[4,5-c]quinolin-4-one derivatives bearing different substituents at position-2 and on the fused benzo ring.
Calabri FR; Colotta V; Catarzi D; Varano F; Lenzi O; Filacchioni G; Costagli C; Galli A
Eur J Med Chem; 2005 Sep; 40(9):897-907. PubMed ID: 15919134
[TBL] [Abstract][Full Text] [Related]
11. Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4-dione scaffold to obtain AMPA and kainate receptor selective antagonists. Synthesis, pharmacological, and molecular modeling studies.
Colotta V; Catarzi D; Varano F; Lenzi O; Filacchioni G; Costagli C; Galli A; Ghelardini C; Galeotti N; Gratteri P; Sgrignani J; Deflorian F; Moro S
J Med Chem; 2006 Oct; 49(20):6015-26. PubMed ID: 17004715
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and SAR of substituted pyrazolo[1,5-a]quinazolines as dual mGlu(2)/mGlu(3) NAMs.
Wenthur CJ; Morrison RD; Daniels JS; Conn PJ; Lindsley CW
Bioorg Med Chem Lett; 2014 Jun; 24(12):2693-8. PubMed ID: 24794112
[TBL] [Abstract][Full Text] [Related]
13. Design, facile synthesis, and evaluation of novel spiro- and pyrazolo[1,5-c]quinazolines as cholinesterase inhibitors: Molecular docking and MM/GBSA studies.
Gálvez J; Polo S; Insuasty B; Gutiérrez M; Cáceres D; Alzate-Morales JH; De-la-Torre P; Quiroga J
Comput Biol Chem; 2018 Jun; 74():218-229. PubMed ID: 29655025
[TBL] [Abstract][Full Text] [Related]
14. Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
Randle JC; Guet T; Bobichon C; Moreau C; Curutchet P; Lambolez B; de Carvalho LP; Cordi A; Lepagnol JM
Mol Pharmacol; 1992 Feb; 41(2):337-45. PubMed ID: 1371583
[TBL] [Abstract][Full Text] [Related]
15. Structure-activity relationships in a series of 2(1H)-quinolones bearing different acidic function in the 3-position: 6,7-dichloro-2(1H)-oxoquinoline-3-phosphonic acid, a new potent and selective AMPA/kainate antagonist with neuroprotective properties.
Desos P; Lepagnol JM; Morain P; Lestage P; Cordi AA
J Med Chem; 1996 Jan; 39(1):197-206. PubMed ID: 8568808
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of glycine site antagonists of the NMDA receptor in global cerebral ischaemia.
Hicks CA; Ward MA; Ragumoorthy N; Ambler SJ; Dell CP; Dobson D; O'Neill MJ
Brain Res; 1999 Feb; 819(1-2):65-74. PubMed ID: 10082862
[TBL] [Abstract][Full Text] [Related]
17. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
Baraldi PG; Fruttarolo F; Tabrizi MA; Preti D; Romagnoli R; El-Kashef H; Moorman A; Varani K; Gessi S; Merighi S; Borea PA
J Med Chem; 2003 Mar; 46(7):1229-41. PubMed ID: 12646033
[TBL] [Abstract][Full Text] [Related]
18. Synthesis of a set of ethyl 1-carbamoyl-3-oxoquinoxaline-2-carboxylates and of their constrained analogue imidazo.
Varano F; Catarzi D; Colotta V; Cecchi L; Filacchioni G; Galli A; Costagli C
Eur J Med Chem; 2001 Feb; 36(2):203-9. PubMed ID: 11311751
[TBL] [Abstract][Full Text] [Related]
19. Analogs of 3-hydroxy-1H-1-benzazepine-2,5-dione: structure-activity relationship at N-methyl-D-aspartate receptor glycine sites.
Guzikowski AP; Cai SX; Espitia SA; Hawkinson JE; Huettner JE; Nogales DF; Tran M; Woodward RM; Weber E; Keana JF
J Med Chem; 1996 Nov; 39(23):4643-53. PubMed ID: 8917653
[TBL] [Abstract][Full Text] [Related]
20. Characterization of indole-2-carboxylate derivatives as antagonists of N-methyl-D-aspartate receptor activity at the associated glycine recognition site.
Hood WF; Gray NM; Dappen MS; Watson GB; Compton RP; Cordi AA; Lanthorn TH; Monahan JB
J Pharmacol Exp Ther; 1992 Aug; 262(2):654-60. PubMed ID: 1386886
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
