These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 19652529)

  • 1. RAKing in AKT: a tumor suppressor function for the intracellular tyrosine kinase FRK.
    Brauer PM; Tyner AL
    Cell Cycle; 2009 Sep; 8(17):2728-32. PubMed ID: 19652529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.
    Kwak YD; Wang B; Pan W; Xu H; Jiang X; Liao FF
    J Biol Chem; 2010 Mar; 285(13):9847-9857. PubMed ID: 20100827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.
    Ahn Y; Hwang CY; Lee SR; Kwon KS; Lee C
    Biochem J; 2008 Jun; 412(2):331-8. PubMed ID: 18307411
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Understanding the cellular roles of Fyn-related kinase (FRK): implications in cancer biology.
    Goel RK; Lukong KE
    Cancer Metastasis Rev; 2016 Jun; 35(2):179-99. PubMed ID: 27067725
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of Neural Precursor Cell Expressed Developmentally Downregulated 4-1 is Associated with Poor Prognosis and Chemoresistance in Lung Adenocarcinoma.
    Song YH; Zhang CQ; Chen FF; Lin XY
    Chin Med J (Engl); 2018 Jan; 131(1):16-24. PubMed ID: 29271375
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rak functions as a tumor suppressor by regulating PTEN protein stability and function.
    Yim EK; Peng G; Dai H; Hu R; Li K; Lu Y; Mills GB; Meric-Bernstam F; Hennessy BT; Craven RJ; Lin SY
    Cancer Cell; 2009 Apr; 15(4):304-14. PubMed ID: 19345329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. NEDD4 is overexpressed in colorectal cancer and promotes colonic cell growth independently of the PI3K/PTEN/AKT pathway.
    Eide PW; Cekaite L; Danielsen SA; Eilertsen IA; Kjenseth A; Fykerud TA; Ågesen TH; Bruun J; Rivedal E; Lothe RA; Leithe E
    Cell Signal; 2013 Jan; 25(1):12-8. PubMed ID: 22974840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Rak/Frk tyrosine kinase associates with and internalizes the epidermal growth factor receptor.
    Jin L; Craven RJ
    Oncogene; 2014 Jan; 33(3):326-35. PubMed ID: 23318459
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.
    Lu Y; Yu Q; Liu JH; Zhang J; Wang H; Koul D; McMurray JS; Fang X; Yung WK; Siminovitch KA; Mills GB
    J Biol Chem; 2003 Oct; 278(41):40057-66. PubMed ID: 12869565
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor.
    Zheng Y; Peng M; Wang Z; Asara JM; Tyner AL
    Mol Cell Biol; 2010 Sep; 30(17):4280-92. PubMed ID: 20606012
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway.
    Jung S; Li C; Jeong D; Lee S; Ohk J; Park M; Han S; Duan J; Kim C; Yang Y; Kim KI; Lim JS; Kang YS; Lee MS
    Int J Oncol; 2013 Nov; 43(5):1587-95. PubMed ID: 23970032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway.
    Liu J; Wan L; Liu P; Inuzuka H; Liu J; Wang Z; Wei W
    Oncotarget; 2014 Feb; 5(4):1026-37. PubMed ID: 24657926
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT.
    Zheng Y; Gierut J; Wang Z; Miao J; Asara JM; Tyner AL
    Oncogene; 2013 Sep; 32(36):4304-12. PubMed ID: 23027128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. E3 ubiquitin ligase Cbl-b regulates Pten via Nedd4 in T cells independently of its ubiquitin ligase activity.
    Guo H; Qiao G; Ying H; Li Z; Zhao Y; Liang Y; Yang L; Lipkowitz S; Penninger JM; Langdon WY; Zhang J
    Cell Rep; 2012 May; 1(5):472-82. PubMed ID: 22763434
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphatase and tensin homolog deleted on chromosome 10 degradation induced by NEDD4 promotes acquired erlotinib resistance in non-small-cell lung cancer.
    Sun H; Ma H; Wang J; Xia L; Zhu G; Wang Z; Sun J; Chen Z
    Tumour Biol; 2017 Jul; 39(7):1010428317709639. PubMed ID: 28714370
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The E3 ubiquitin ligase NEDD4 is translationally upregulated and facilitates pancreatic cancer.
    Weng M; Luo ZL; Wu XL; Zeng WZ
    Oncotarget; 2017 Mar; 8(12):20288-20296. PubMed ID: 28423617
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers.
    Fedele CG; Ooms LM; Ho M; Vieusseux J; O'Toole SA; Millar EK; Lopez-Knowles E; Sriratana A; Gurung R; Baglietto L; Giles GG; Bailey CG; Rasko JE; Shields BJ; Price JT; Majerus PW; Sutherland RL; Tiganis T; McLean CA; Mitchell CA
    Proc Natl Acad Sci U S A; 2010 Dec; 107(51):22231-6. PubMed ID: 21127264
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ubiquitin ligase Nedd4-1 is dispensable for the regulation of PTEN stability and localization.
    Fouladkou F; Landry T; Kawabe H; Neeb A; Lu C; Brose N; Stambolic V; Rotin D
    Proc Natl Acad Sci U S A; 2008 Jun; 105(25):8585-90. PubMed ID: 18562292
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ubiquitin E3 ligase Nedd4-1 acts as a downstream target of PI3K/PTEN-mTORC1 signaling to promote neurite growth.
    Hsia HE; Kumar R; Luca R; Takeda M; Courchet J; Nakashima J; Wu S; Goebbels S; An W; Eickholt BJ; Polleux F; Rotin D; Wu H; Rossner MJ; Bagni C; Rhee JS; Brose N; Kawabe H
    Proc Natl Acad Sci U S A; 2014 Sep; 111(36):13205-10. PubMed ID: 25157163
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer.
    Zheng Y; Wang Z; Bie W; Brauer PM; Perez White BE; Li J; Nogueira V; Raychaudhuri P; Hay N; Tonetti DA; Macias V; Kajdacsy-Balla A; Tyner AL
    Cancer Res; 2013 Sep; 73(17):5426-37. PubMed ID: 23856248
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.