BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 19653678)

  • 1. In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents.
    Kim MI; Kwon SJ; Dordick JS
    Org Lett; 2009 Sep; 11(17):3806-9. PubMed ID: 19653678
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB.
    Hughes AJ; Keatinge-Clay A
    Chem Biol; 2011 Feb; 18(2):165-76. PubMed ID: 21338915
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Exploring the Promiscuous Enzymatic Activation of Unnatural Polyketide Extender Units in Vitro and in Vivo for Monensin Biosynthesis.
    Grote M; Schulz F
    Chembiochem; 2019 May; 20(9):1183-1189. PubMed ID: 30629783
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase.
    Adhikari K; Lo IW; Chen CL; Wang YL; Lin KH; Zadeh SM; Rattinam R; Li YS; Wu CJ; Li TL
    Biomolecules; 2020 May; 10(5):. PubMed ID: 32397467
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unnatural polyketide analogues selectively target the HER signaling pathway in human breast cancer cells.
    Kwon SJ; Kim MI; Ku B; Coulombel L; Kim JH; Shawky JH; Linhardt RJ; Dordick JS
    Chembiochem; 2010 Mar; 11(4):573-80. PubMed ID: 20058253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural control of polyketide formation in plant-specific polyketide synthases.
    Jez JM; Austin MB; Ferrer J; Bowman ME; Schröder J; Noel JP
    Chem Biol; 2000 Dec; 7(12):919-30. PubMed ID: 11137815
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates.
    Tosin M; Spiteller D; Spencer JB
    Chembiochem; 2009 Jul; 10(10):1714-23. PubMed ID: 19507202
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Middle Chain Fatty Acyl-CoA Ligase Responsible for the Biosynthesis of 2-Alkylmalonyl-CoAs for Polyketide Extender Unit.
    Miyazawa T; Takahashi S; Kawata A; Panthee S; Hayashi T; Shimizu T; Nogawa T; Osada H
    J Biol Chem; 2015 Nov; 290(45):26994-27011. PubMed ID: 26378232
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Engineered biosynthesis of plant polyketides: chain length control in an octaketide-producing plant type III polyketide synthase.
    Abe I; Oguro S; Utsumi Y; Sano Y; Noguchi H
    J Am Chem Soc; 2005 Sep; 127(36):12709-16. PubMed ID: 16144421
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Engineered biosynthesis of plant polyketides: manipulation of chalcone synthase.
    Abe I; Watanabe T; Morita H; Kohno T; Noguchi H
    Org Lett; 2006 Feb; 8(3):499-502. PubMed ID: 16435869
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enzymatic formation of long-chain polyketide pyrones by plant type III polyketide synthases.
    Abe I; Watanabe T; Noguchi H
    Phytochemistry; 2004 Sep; 65(17):2447-53. PubMed ID: 15381408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-guided programming of polyketide chain-length determination in chalcone synthase.
    Jez JM; Bowman ME; Noel JP
    Biochemistry; 2001 Dec; 40(49):14829-38. PubMed ID: 11732902
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carnitine palmityltransferase and its relation to palmityl-CoA synthetase in blood platelets from fasting, healthy subjects.
    Sander J; Farstad M
    Scand J Clin Lab Invest; 1973 Oct; 32(2):183-8. PubMed ID: 4768304
    [No Abstract]   [Full Text] [Related]  

  • 14. Rapid preparation of (methyl)malonyl coenzyme A and enzymatic formation of unusual polyketides by type III polyketide synthase from Aquilaria sinensis.
    Gao BW; Wang XH; Liu X; Shi SP; Tu PF
    Bioorg Med Chem Lett; 2015 Mar; 25(6):1279-83. PubMed ID: 25677661
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence that two covalent intermediates, phosphoryl and malonyl enzymes, are formed during malonyl-coenzyme A synthetase catalysis.
    Kim YS; Lee JK
    J Biol Chem; 1986 Dec; 261(35):16295-7. PubMed ID: 3097006
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
    Jez JM; Ferrer JL; Bowman ME; Dixon RA; Noel JP
    Biochemistry; 2000 Feb; 39(5):890-902. PubMed ID: 10653632
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The active site and substrates binding mode of malonyl-CoA synthetase determined by transferred nuclear Overhauser effect spectroscopy, site-directed mutagenesis, and comparative modeling studies.
    Jung JW; An JH; Na KB; Kim YS; Lee W
    Protein Sci; 2000 Jul; 9(7):1294-303. PubMed ID: 10933494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus.
    Funa N; Ohnishi Y; Ebizuka Y; Horinouchi S
    J Biol Chem; 2002 Feb; 277(7):4628-35. PubMed ID: 11723138
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of a pentaketide stilbene produced by a type III polyketide synthase from Pinus sylvestris and characterisation of free coenzyme A intermediates.
    Li TL; Spiteller D; Spencer JB
    Chembiochem; 2009 Mar; 10(5):896-901. PubMed ID: 19266535
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expanding the biosynthetic repertoire of plant type III polyketide synthases by altering starter molecule specificity.
    Jez JM; Bowman ME; Noel JP
    Proc Natl Acad Sci U S A; 2002 Apr; 99(8):5319-24. PubMed ID: 11959984
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.