BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 19654569)

  • 1. Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease.
    Hudry E; Van Dam D; Kulik W; De Deyn PP; Stet FS; Ahouansou O; Benraiss A; Delacourte A; Bougnères P; Aubourg P; Cartier N
    Mol Ther; 2010 Jan; 18(1):44-53. PubMed ID: 19654569
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.
    Burlot MA; Braudeau J; Michaelsen-Preusse K; Potier B; Ayciriex S; Varin J; Gautier B; Djelti F; Audrain M; Dauphinot L; Fernandez-Gomez FJ; Caillierez R; Laprévote O; Bièche I; Auzeil N; Potier MC; Dutar P; Korte M; Buée L; Blum D; Cartier N
    Hum Mol Genet; 2015 Nov; 24(21):5965-76. PubMed ID: 26358780
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential expression of cholesterol hydroxylases in Alzheimer's disease.
    Brown J; Theisler C; Silberman S; Magnuson D; Gottardi-Littell N; Lee JM; Yager D; Crowley J; Sambamurti K; Rahman MM; Reiss AB; Eckman CB; Wolozin B
    J Biol Chem; 2004 Aug; 279(33):34674-81. PubMed ID: 15148325
    [TBL] [Abstract][Full Text] [Related]  

  • 4. CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer's disease.
    Djelti F; Braudeau J; Hudry E; Dhenain M; Varin J; Bièche I; Marquer C; Chali F; Ayciriex S; Auzeil N; Alves S; Langui D; Potier MC; Laprevote O; Vidaud M; Duyckaerts C; Miles R; Aubourg P; Cartier N
    Brain; 2015 Aug; 138(Pt 8):2383-98. PubMed ID: 26141492
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Adeno-associated viral (AAV) serotype 5 vector mediated gene delivery of endothelin-converting enzyme reduces Abeta deposits in APP + PS1 transgenic mice.
    Carty NC; Nash K; Lee D; Mercer M; Gottschall PE; Meyers C; Muzyczka N; Gordon MN; Morgan D
    Mol Ther; 2008 Sep; 16(9):1580-6. PubMed ID: 18665160
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.
    Zhao L; Gottesdiener AJ; Parmar M; Li M; Kaminsky SM; Chiuchiolo MJ; Sondhi D; Sullivan PM; Holtzman DM; Crystal RG; Paul SM
    Neurobiol Aging; 2016 Aug; 44():159-172. PubMed ID: 27318144
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan.
    Halford RW; Russell DW
    Proc Natl Acad Sci U S A; 2009 Mar; 106(9):3502-6. PubMed ID: 19204288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Anti-Abeta single-chain antibody delivery via adeno-associated virus for treatment of Alzheimer's disease.
    Fukuchi K; Tahara K; Kim HD; Maxwell JA; Lewis TL; Accavitti-Loper MA; Kim H; Ponnazhagan S; Lalonde R
    Neurobiol Dis; 2006 Sep; 23(3):502-11. PubMed ID: 16766200
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer's disease pathology in mice.
    Djogo N; Jakovcevski I; Müller C; Lee HJ; Xu JC; Jakovcevski M; Kügler S; Loers G; Schachner M
    Neurobiol Dis; 2013 Aug; 56():104-15. PubMed ID: 23639788
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Abeta-directed single-chain antibody delivery via a serotype-1 AAV vector improves learning behavior and pathology in Alzheimer's disease mice.
    Ryan DA; Mastrangelo MA; Narrow WC; Sullivan MA; Federoff HJ; Bowers WJ
    Mol Ther; 2010 Aug; 18(8):1471-81. PubMed ID: 20551911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism.
    Kölsch H; Lütjohann D; Jessen F; Popp J; Hentschel F; Kelemen P; Schmitz S; Maier W; Heun R
    Eur Psychiatry; 2009 Apr; 24(3):183-90. PubMed ID: 19286353
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse.
    Meljon A; Wang Y; Griffiths WJ
    Biochem Biophys Res Commun; 2014 Apr; 446(3):768-74. PubMed ID: 24491562
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gene therapy for Alzheimer's disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation.
    Griciuc A; Federico AN; Natasan J; Forte AM; McGinty D; Nguyen H; Volak A; LeRoy S; Gandhi S; Lerner EP; Hudry E; Tanzi RE; Maguire CA
    Hum Mol Genet; 2020 Oct; 29(17):2920-2935. PubMed ID: 32803224
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Peripheral transgene expression of plasma gelsolin reduces amyloid in transgenic mouse models of Alzheimer's disease.
    Hirko AC; Meyer EM; King MA; Hughes JA
    Mol Ther; 2007 Sep; 15(9):1623-9. PubMed ID: 17609655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease.
    Kanninen K; Heikkinen R; Malm T; Rolova T; Kuhmonen S; Leinonen H; Ylä-Herttuala S; Tanila H; Levonen AL; Koistinaho M; Koistinaho J
    Proc Natl Acad Sci U S A; 2009 Sep; 106(38):16505-10. PubMed ID: 19805328
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Cholesterol and Alzheimer's disease].
    Kálmán J; Janka Z
    Orv Hetil; 2005 Sep; 146(37):1903-11. PubMed ID: 16255374
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 27-hydroxycholesterol promotes Aβ accumulation via altering Aβ metabolism in mild cognitive impairment patients and APP/PS1 mice.
    Zhang X; Xi Y; Yu H; An Y; Wang Y; Tao L; Wang Y; Liu W; Wang T; Xiao R
    Brain Pathol; 2019 Jul; 29(4):558-573. PubMed ID: 30582229
    [TBL] [Abstract][Full Text] [Related]  

  • 18. AAV2/1 CD74 Gene Transfer Reduces β-amyloidosis and Improves Learning and Memory in a Mouse Model of Alzheimer's Disease.
    Kiyota T; Zhang G; Morrison CM; Bosch ME; Weir RA; Lu Y; Dong W; Gendelman HE
    Mol Ther; 2015 Nov; 23(11):1712-1721. PubMed ID: 26227349
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model.
    Fol R; Braudeau J; Ludewig S; Abel T; Weyer SW; Roederer JP; Brod F; Audrain M; Bemelmans AP; Buchholz CJ; Korte M; Cartier N; Müller UC
    Acta Neuropathol; 2016 Feb; 131(2):247-266. PubMed ID: 26538149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Intracranial adeno-associated virus-mediated delivery of anti-pan amyloid beta, amyloid beta40, and amyloid beta42 single-chain variable fragments attenuates plaque pathology in amyloid precursor protein mice.
    Levites Y; Jansen K; Smithson LA; Dakin R; Holloway VM; Das P; Golde TE
    J Neurosci; 2006 Nov; 26(46):11923-8. PubMed ID: 17108166
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.