BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

406 related articles for article (PubMed ID: 19655752)

  • 1. Origins of the distortions in the base pair step adjacent to platinum anticancer drug-DNA adducts. Fundamental NMR solution studies utilizing right-handed cross-link models having 5'- and 3'-flanking residues.
    Saad JS; Natile G; Marzilli LG
    J Am Chem Soc; 2009 Sep; 131(34):12314-24. PubMed ID: 19655752
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Single-stranded oligonucleotide adducts formed by Pt complexes favoring left-handed base canting: steric effect of flanking residues and relevance to DNA adducts formed by Pt anticancer drugs.
    Saad JS; Marzilli PA; Intini FP; Natile G; Marzilli LG
    Inorg Chem; 2011 Sep; 50(17):8608-20. PubMed ID: 21819051
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dramatic 5'-residue effect on conformer distribution of short oligonucleotide retro models of the cisplatin-DNA cross-link: implications for the Lippard and cross-link distorted base pair steps present in cisplatin-DNA duplex adducts.
    Sullivan ST; Saad JS; Fanizzi FP; Marzilli LG
    J Am Chem Soc; 2002 Feb; 124(8):1558-9. PubMed ID: 11853413
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NMR studies of models having the Pt(d(GpG)) 17-membered macrocyclic ring formed in DNA by platinum anticancer drugs: Pt complexes with bulky chiral diamine ligands.
    Saad JS; Benedetti M; Natile G; Marzilli LG
    Inorg Chem; 2011 May; 50(10):4559-71. PubMed ID: 21510625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A rare example of three abundant conformers in one retro model of the cisplatin-DNA d(GpG) intrastrand cross link. Unambiguous evidence that guanine O6 to carrier amine ligand hydrogen bonding is not important. possible effect of the Lippard base pair step adjacent to the lesion on carrier ligand hydrogen bonding in DNA adducts.
    Sullivan ST; Ciccarese A; Fanizzi FP; Marzilli LG
    J Am Chem Soc; 2001 Sep; 123(38):9345-55. PubMed ID: 11562217
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Marked dependence on carrier-ligand bulk but not on carrier-ligand chirality of the duplex versus single-strand forms of a DNA oligonucleotide with a series of G-Pt(II)-G intrastrand cross-links modeling cisplatin-DNA adducts.
    Beljanski V; Villanueva JM; Doetsch PW; Natile G; Marzilli LG
    J Am Chem Soc; 2005 Nov; 127(45):15833-42. PubMed ID: 16277526
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Investigation relevant to the conformation of the 17-membered Pt(d(GpG)) macrocyclic ring formed by Pt anticancer drugs with DNA: Pt complexes with a Goldilocks carrier ligand.
    Maheshwari V; Marzilli PA; Marzilli LG
    Inorg Chem; 2011 Jul; 50(14):6626-36. PubMed ID: 21667929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects.
    Kankia BI; Soto AM; Burns N; Shikiya R; Tung CS; Marky LA
    Biopolymers; 2002 Nov; 65(3):218-27. PubMed ID: 12228927
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exploring the universality of unusual conformations of the 17-membered Pt(d(G*pG*)) macrochelate ring. Dependence of conformer formation on a change in bidentate carrier ligand from an sp3 to an sp2 nitrogen donor.
    Bhattacharyya D; Marzilli PA; Marzilli LG
    Inorg Chem; 2005 Oct; 44(21):7644-51. PubMed ID: 16212391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Head-to-head cross-linked adduct between the antitumor unit bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) and the DNA fragment d(GpG).
    Chifotides HT; Dunbar KR
    Chemistry; 2006 Aug; 12(25):6458-68. PubMed ID: 16900545
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Basic coordination chemistry relevant to DNA adducts formed by the cisplatin anticancer drug. NMR studies on compounds with sterically crowded chiral ligands.
    Saad JS; Benedetti M; Natile G; Marzilli LG
    Inorg Chem; 2010 Jun; 49(12):5573-83. PubMed ID: 20496875
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin.
    Gelasco A; Lippard SJ
    Biochemistry; 1998 Jun; 37(26):9230-9. PubMed ID: 9649303
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cisplatin adducts on a GGG sequence within a DNA duplex studied by NMR spectroscopy and molecular dynamics simulations.
    Téletchéa S; Skauge T; Sletten E; Kozelka J
    Chemistry; 2009 Nov; 15(45):12320-37. PubMed ID: 19813235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II).
    Chifotides HT; Koshlap KM; Pérez LM; Dunbar KR
    J Am Chem Soc; 2003 Sep; 125(35):10714-24. PubMed ID: 12940757
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II).
    Chifotides HT; Koshlap KM; Pérez LM; Dunbar KR
    J Am Chem Soc; 2003 Sep; 125(35):10703-13. PubMed ID: 12940756
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Solution structural study of a DNA duplex containing the guanine-N7 adduct formed by a cytotoxic platinum-acridine hybrid agent.
    Baruah H; Wright MW; Bierbach U
    Biochemistry; 2005 Apr; 44(16):6059-70. PubMed ID: 15835895
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
    Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N
    Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA.
    Pilch DS; Dunham SU; Jamieson ER; Lippard SJ; Breslauer KJ
    J Mol Biol; 2000 Feb; 296(3):803-12. PubMed ID: 10677282
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modification of second-sphere communication, leading to an unusually high abundance of the head-to-head conformer of cisplatin cross-link retro models.
    Saad JS; Scarcia T; Shinozuka K; Natile G; Marzilli LG
    Inorg Chem; 2002 Feb; 41(3):546-57. PubMed ID: 11825082
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Site-specific d(GpG) intrastrand cross-links formed by dinuclear platinum complexes. Bending and NMR studies.
    Kaspárková J; Mellish KJ; Qu Y; Brabec V; Farrell N
    Biochemistry; 1996 Dec; 35(51):16705-13. PubMed ID: 8988007
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.