BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

392 related articles for article (PubMed ID: 19660548)

  • 1. Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1.
    Witan H; Gorlovoy P; Kaya AM; Koziollek-Drechsler I; Neumann H; Behl C; Clement AM
    Neurobiol Dis; 2009 Nov; 36(2):331-42. PubMed ID: 19660548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Heterodimer formation of wild-type and amyotrophic lateral sclerosis-causing mutant Cu/Zn-superoxide dismutase induces toxicity independent of protein aggregation.
    Witan H; Kern A; Koziollek-Drechsler I; Wade R; Behl C; Clement AM
    Hum Mol Genet; 2008 May; 17(10):1373-85. PubMed ID: 18211954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stabilization of mutant Cu/Zn superoxide dismutase (SOD1) protein by coexpressed wild SOD1 protein accelerates the disease progression in familial amyotrophic lateral sclerosis mice.
    Fukada K; Nagano S; Satoh M; Tohyama C; Nakanishi T; Shimizu A; Yanagihara T; Sakoda S
    Eur J Neurosci; 2001 Dec; 14(12):2032-6. PubMed ID: 11860498
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
    Turner BJ; Lopes EC; Cheema SS
    J Cell Biochem; 2004 Apr; 91(5):1074-84. PubMed ID: 15034941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.
    Oh YK; Shin KS; Yuan J; Kang SJ
    J Neurochem; 2008 Feb; 104(4):993-1005. PubMed ID: 18233996
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.
    Weichert A; Besemer AS; Liebl M; Hellmann N; Koziollek-Drechsler I; Ip P; Decker H; Robertson J; Chakrabartty A; Behl C; Clement AM
    Neurobiol Dis; 2014 Feb; 62():479-88. PubMed ID: 24200866
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.
    Vijayvergiya C; Beal MF; Buck J; Manfredi G
    J Neurosci; 2005 Mar; 25(10):2463-70. PubMed ID: 15758154
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.
    Watanabe M; Dykes-Hoberg M; Culotta VC; Price DL; Wong PC; Rothstein JD
    Neurobiol Dis; 2001 Dec; 8(6):933-41. PubMed ID: 11741389
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure, folding, and misfolding of Cu,Zn superoxide dismutase in amyotrophic lateral sclerosis.
    Rakhit R; Chakrabartty A
    Biochim Biophys Acta; 2006; 1762(11-12):1025-37. PubMed ID: 16814528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis.
    Watanabe S; Nagano S; Duce J; Kiaei M; Li QX; Tucker SM; Tiwari A; Brown RH; Beal MF; Hayward LJ; Culotta VC; Yoshihara S; Sakoda S; Bush AI
    Free Radic Biol Med; 2007 May; 42(10):1534-42. PubMed ID: 17448900
    [TBL] [Abstract][Full Text] [Related]  

  • 12. TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase.
    Higashi S; Tsuchiya Y; Araki T; Wada K; Kabuta T
    Neurochem Int; 2010 Dec; 57(8):906-13. PubMed ID: 20933032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cu/Zn superoxide dismutase (SOD1) mutations associated with familial amyotrophic lateral sclerosis (ALS) affect cellular free radical release in the presence of oxidative stress.
    Cookson MR; Menzies FM; Manning P; Eggett CJ; Figlewicz DA; McNeil CJ; Shaw PJ
    Amyotroph Lateral Scler Other Motor Neuron Disord; 2002 Jun; 3(2):75-85. PubMed ID: 12215229
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of three mutations in the Cu,Zn-superoxide dismutase (Cu,Zn-SOD) gene with familial amyotrophic lateral sclerosis: transduction of human Cu,Zn-SOD into PC12 cells by HIV-1 TAT protein basic domain.
    Chou CM; Huang CJ; Shih CM; Chen YP; Liu TP; Chen CT
    Ann N Y Acad Sci; 2005 May; 1042():303-13. PubMed ID: 15965076
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
    Wang J; Xu G; Slunt HH; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
    Neurobiol Dis; 2005 Dec; 20(3):943-52. PubMed ID: 16046140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Metalation of the amyotrophic lateral sclerosis mutant glycine 37 to arginine superoxide dismutase (SOD1) apoprotein restores its structural and dynamical properties in solution to those of metalated wild-type SOD1.
    Banci L; Bertini I; D'Amelio N; Libralesso E; Turano P; Valentine JS
    Biochemistry; 2007 Sep; 46(35):9953-62. PubMed ID: 17683122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutation-dependent polymorphism of Cu,Zn-superoxide dismutase aggregates in the familial form of amyotrophic lateral sclerosis.
    Furukawa Y; Kaneko K; Yamanaka K; Nukina N
    J Biol Chem; 2010 Jul; 285(29):22221-31. PubMed ID: 20404329
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dimerization, oligomerization, and aggregation of human amyotrophic lateral sclerosis copper/zinc superoxide dismutase 1 protein mutant forms in live cells.
    Kim J; Lee H; Lee JH; Kwon DY; Genovesio A; Fenistein D; Ogier A; Brondani V; Grailhe R
    J Biol Chem; 2014 May; 289(21):15094-103. PubMed ID: 24692554
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ALS-causing SOD1 mutations promote production of copper-deficient misfolded species.
    Ip P; Mulligan VK; Chakrabartty A
    J Mol Biol; 2011 Jun; 409(5):839-52. PubMed ID: 21549128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis.
    Urushitani M; Sik A; Sakurai T; Nukina N; Takahashi R; Julien JP
    Nat Neurosci; 2006 Jan; 9(1):108-18. PubMed ID: 16369483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.