BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 19661327)

  • 1. Induction of mitotic arrest and apoptosis by a novel synthetic quinolone analogue, CWC-8, via intrinsic and extrinsic apoptotic pathways in human osteogenic sarcoma U-2 OS cells.
    Chang YH; Yang JS; Kuo SC; Chung JG
    Anticancer Res; 2009 Aug; 29(8):3139-48. PubMed ID: 19661327
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line.
    Hsu SC; Yang JS; Kuo CL; Lo C; Lin JP; Hsia TC; Lin JJ; Lai KC; Kuo HM; Huang LJ; Kuo SC; Wood WG; Chung JG
    J Orthop Res; 2009 Dec; 27(12):1637-44. PubMed ID: 19557855
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC; Lu PH; Pan SL; Teng CM; Kuo SC; Lin TP; Ho YF; Huang YC; Guh JH
    Biochem Pharmacol; 2007 Jun; 74(1):10-9. PubMed ID: 17475221
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells.
    Huang SM; Yang JS; Tsai SC; Chen MH; Hsu MH; Lin HY; Chou LC; Chinag JH; Lee KH; Huang LJ; Kuo SC
    Int J Oncol; 2011 May; 38(5):1357-64. PubMed ID: 21344160
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL; Huang AC; Yang JS; Liao CL; Lu HF; Chou ST; Ma CY; Hsia TC; Ko YC; Chung JG
    J Orthop Res; 2011 Aug; 29(8):1199-209. PubMed ID: 21374707
    [TBL] [Abstract][Full Text] [Related]  

  • 6. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.
    Yang JS; Hour MJ; Huang WW; Lin KL; Kuo SC; Chung JG
    J Pharmacol Exp Ther; 2010 Aug; 334(2):477-88. PubMed ID: 20463006
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS).
    Lu KH; Lue KH; Chou MC; Chung JG
    J Orthop Res; 2005 Sep; 23(5):988-94. PubMed ID: 16140185
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.
    Chiu YJ; Hour MJ; Lu CC; Chung JG; Kuo SC; Huang WW; Chen HJ; Jin YA; Yang JS
    J Orthop Res; 2011 Sep; 29(9):1448-56. PubMed ID: 21425328
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways.
    Huang WW; Ko SW; Tsai HY; Chung JG; Chiang JH; Chen KT; Chen YC; Chen HY; Chen YF; Yang JS
    Int J Oncol; 2011 Apr; 38(4):1067-73. PubMed ID: 21271215
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 7-Chloro-6-piperidin-1-yl-quinoline-5,8-dione (PT-262), a novel synthetic compound induces lung carcinoma cell death associated with inhibiting ERK and CDC2 phosphorylation via a p53-independent pathway.
    Hsu TS; Chen C; Lee PT; Chiu SJ; Liu HF; Tsai CC; Chao JI
    Cancer Chemother Pharmacol; 2008 Oct; 62(5):799-808. PubMed ID: 18193228
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Induction of G2 /M phase arrest and apoptosis of MCF-7 cells by novel benzofuran lignan via suppressing cell cycle proteins].
    Yang H; Cai YC; Pang JY; Li YQ; Zeng ZL; Xu ZL; Xian LJ
    Yao Xue Xue Bao; 2008 Feb; 43(2):138-44. PubMed ID: 18507339
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
    Chang JY; Chang CY; Kuo CC; Chen LT; Wein YS; Kuo YH
    Mol Pharmacol; 2004 Jan; 65(1):77-84. PubMed ID: 14722239
    [TBL] [Abstract][Full Text] [Related]  

  • 13. (-)-Epigallocatechin gallate induced apoptosis in human adrenal cancer NCI-H295 cells through caspase-dependent and caspase-independent pathway.
    Wu PP; Kuo SC; Huang WW; Yang JS; Lai KC; Chen HJ; Lin KL; Chiu YJ; Huang LJ; Chung JG
    Anticancer Res; 2009 Apr; 29(4):1435-42. PubMed ID: 19414399
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gadolinium chloride elicits apoptosis in human osteosarcoma U-2 OS cells through extrinsic signaling, intrinsic pathway and endoplasmic reticulum stress.
    Tsai YF; Huang CW; Chiang JH; Tsai FJ; Hsu YM; Lu CC; Hsiao CY; Yang JS
    Oncol Rep; 2016 Dec; 36(6):3421-3426. PubMed ID: 27748868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The novel synthesized 6-fluoro-(3-fluorophenyl)-4-(3-methoxyanilino)quinazoline (LJJ-10) compound exhibits anti-metastatic effects in human osteosarcoma U-2 OS cells through targeting insulin-like growth factor-I receptor.
    Chen KT; Hour MJ; Tsai SC; Chung JG; Kuo SC; Lu CC; Chiu YJ; Chuang YH; Yang JS
    Int J Oncol; 2011 Sep; 39(3):611-9. PubMed ID: 21667022
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Smh-3 induces G(2)/M arrest and apoptosis through calcium‑mediated endoplasmic reticulum stress and mitochondrial signaling in human hepatocellular carcinoma Hep3B cells.
    Liu CY; Yang JS; Huang SM; Chiang JH; Chen MH; Huang LJ; Ha HY; Fushiya S; Kuo SC
    Oncol Rep; 2013 Feb; 29(2):751-62. PubMed ID: 23233035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The crude extract of Corni Fructus induces apoptotic cell death through reactive oxygen species-modulated pathways in U-2 OS human osteosarcoma cells.
    Liao CL; Hsu SC; Yu CC; Yang JS; Tang NY; Wood WG; Lin JG; Chung JG
    Environ Toxicol; 2014 Sep; 29(9):1020-31. PubMed ID: 23239598
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H; Ishii Y; Hirano T; Stoiber T; Camacho Gomez JA; Schmidt P; Düssmann H; Burger AM; Prehn JH; Günther EG; Unger E; Umezawa K
    J Med Chem; 2003 Jul; 46(15):3382-94. PubMed ID: 12852768
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel indoloquinoline derivative, IQDMA, induces G(2)/M phase arrest and apoptosis in A549 cells through JNK/p38 MAPK signaling activation.
    Su JC; Lin KL; Chien CM; Lu CM; Chen YL; Chang LS; Lin SR
    Life Sci; 2009 Sep; 85(13-14):505-16. PubMed ID: 19699753
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways.
    Gazitt Y; Kolaparthi V; Moncada K; Thomas C; Freeman J
    Int J Oncol; 2009 Feb; 34(2):551-61. PubMed ID: 19148492
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.