245 related articles for article (PubMed ID: 19661462)
1. Using lidocaine and benzocaine to link sodium channel molecular conformations to state-dependent antiarrhythmic drug affinity.
Hanck DA; Nikitina E; McNulty MM; Fozzard HA; Lipkind GM; Sheets MF
Circ Res; 2009 Aug; 105(5):492-9. PubMed ID: 19661462
[TBL] [Abstract][Full Text] [Related]
2. Outward stabilization of the S4 segments in domains III and IV enhances lidocaine block of sodium channels.
Sheets MF; Hanck DA
J Physiol; 2007 Jul; 582(Pt 1):317-34. PubMed ID: 17510181
[TBL] [Abstract][Full Text] [Related]
3. Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.
McNulty MM; Edgerton GB; Shah RD; Hanck DA; Fozzard HA; Lipkind GM
J Physiol; 2007 Jun; 581(Pt 2):741-55. PubMed ID: 17363383
[TBL] [Abstract][Full Text] [Related]
4. Block of inactivation-deficient Na+ channels by local anesthetics in stably transfected mammalian cells: evidence for drug binding along the activation pathway.
Wang SY; Mitchell J; Moczydlowski E; Wang GK
J Gen Physiol; 2004 Dec; 124(6):691-701. PubMed ID: 15545401
[TBL] [Abstract][Full Text] [Related]
5. Sodium channel molecular conformations and antiarrhythmic drug affinity.
Sheets MF; Fozzard HA; Lipkind GM; Hanck DA
Trends Cardiovasc Med; 2010 Jan; 20(1):16-21. PubMed ID: 20685573
[TBL] [Abstract][Full Text] [Related]
6. Lidocaine alters activation gating of cardiac Na channels.
Hanck DA; Makielski JC; Sheets MF
Pflugers Arch; 2000 Apr; 439(6):814-21. PubMed ID: 10784357
[TBL] [Abstract][Full Text] [Related]
7. Important Role of Asparagines in Coupling the Pore and Votage-Sensor Domain in Voltage-Gated Sodium Channels.
Sheets MF; Fozzard HA; Hanck DA
Biophys J; 2015 Dec; 109(11):2277-86. PubMed ID: 26636939
[TBL] [Abstract][Full Text] [Related]
8. Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels.
Ragsdale DS; McPhee JC; Scheuer T; Catterall WA
Proc Natl Acad Sci U S A; 1996 Aug; 93(17):9270-5. PubMed ID: 8799190
[TBL] [Abstract][Full Text] [Related]
9. Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels.
Cummins TR
J Physiol; 2007 Jul; 582(Pt 1):11. PubMed ID: 17525109
[No Abstract] [Full Text] [Related]
10. Local anaesthetic block of sodium channels: raising the barrier.
Scheuer T
J Physiol; 2007 Jun; 581(Pt 2):423. PubMed ID: 17412761
[No Abstract] [Full Text] [Related]
11. Kinetic effects of quaternary lidocaine block of cardiac sodium channels: a gating current study.
Hanck DA; Makielski JC; Sheets MF
J Gen Physiol; 1994 Jan; 103(1):19-43. PubMed ID: 8169596
[TBL] [Abstract][Full Text] [Related]
12. Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine.
Tikhonov DB; Bruhova I; Zhorov BS
FEBS Lett; 2006 Nov; 580(26):6027-32. PubMed ID: 17070808
[TBL] [Abstract][Full Text] [Related]
13. State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.
Wang GK; Calderon J; Wang SY
Mol Pharmacol; 2008 Mar; 73(3):940-8. PubMed ID: 18079277
[TBL] [Abstract][Full Text] [Related]
14. Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels.
Ahern CA; Eastwood AL; Dougherty DA; Horn R
Circ Res; 2008 Jan; 102(1):86-94. PubMed ID: 17967784
[TBL] [Abstract][Full Text] [Related]
15. A Nav1.7 channel mutation associated with hereditary erythromelalgia contributes to neuronal hyperexcitability and displays reduced lidocaine sensitivity.
Sheets PL; Jackson JO; Waxman SG; Dib-Hajj SD; Cummins TR
J Physiol; 2007 Jun; 581(Pt 3):1019-31. PubMed ID: 17430993
[TBL] [Abstract][Full Text] [Related]
16. Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide.
Desaphy JF; Dipalma A; Costanza T; Bruno C; Lentini G; Franchini C; George A; Conte Camerino D
Br J Pharmacol; 2010 Jul; 160(6):1521-33. PubMed ID: 20590641
[TBL] [Abstract][Full Text] [Related]
17. Altered gating and local anesthetic block mediated by residues in the I-S6 and II-S6 transmembrane segments of voltage-dependent Na+ channels.
Kondratiev A; Tomaselli GF
Mol Pharmacol; 2003 Sep; 64(3):741-52. PubMed ID: 12920212
[TBL] [Abstract][Full Text] [Related]
18. Irreversible block of cardiac mutant Na+ channels by batrachotoxin.
Wang SY; Tikhonov DB; Mitchell J; Zhorov BS; Wang GK
Channels (Austin); 2007; 1(3):179-88. PubMed ID: 18690024
[TBL] [Abstract][Full Text] [Related]
19. State-dependent trapping of flecainide in the cardiac sodium channel.
Ramos E; O'leary ME
J Physiol; 2004 Oct; 560(Pt 1):37-49. PubMed ID: 15272045
[TBL] [Abstract][Full Text] [Related]
20. A revised view of cardiac sodium channel "blockade" in the long-QT syndrome.
Kambouris NG; Nuss HB; Johns DC; Marbán E; Tomaselli GF; Balser JR
J Clin Invest; 2000 Apr; 105(8):1133-40. PubMed ID: 10772658
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
