BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

455 related articles for article (PubMed ID: 19668216)

  • 1. Mutations in INPP5E, encoding inositol polyphosphate-5-phosphatase E, link phosphatidyl inositol signaling to the ciliopathies.
    Bielas SL; Silhavy JL; Brancati F; Kisseleva MV; Al-Gazali L; Sztriha L; Bayoumi RA; Zaki MS; Abdel-Aleem A; Rosti RO; Kayserili H; Swistun D; Scott LC; Bertini E; Boltshauser E; Fazzi E; Travaglini L; Field SJ; Gayral S; Jacoby M; Schurmans S; Dallapiccola B; Majerus PW; Valente EM; Gleeson JG
    Nat Genet; 2009 Sep; 41(9):1032-6. PubMed ID: 19668216
    [TBL] [Abstract][Full Text] [Related]  

  • 2. INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse.
    Jacoby M; Cox JJ; Gayral S; Hampshire DJ; Ayub M; Blockmans M; Pernot E; Kisseleva MV; Compère P; Schiffmann SN; Gergely F; Riley JH; Pérez-Morga D; Woods CG; Schurmans S
    Nat Genet; 2009 Sep; 41(9):1027-31. PubMed ID: 19668215
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma.
    Conduit SE; Ramaswamy V; Remke M; Watkins DN; Wainwright BJ; Taylor MD; Mitchell CA; Dyson JM
    Oncogene; 2017 Oct; 36(43):5969-5984. PubMed ID: 28650469
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane.
    Xu W; Jin M; Hu R; Wang H; Zhang F; Yuan S; Cao Y
    J Am Soc Nephrol; 2017 Jan; 28(1):118-129. PubMed ID: 27401686
    [TBL] [Abstract][Full Text] [Related]  

  • 5. INPP5E regulates phosphoinositide-dependent cilia transition zone function.
    Dyson JM; Conduit SE; Feeney SJ; Hakim S; DiTommaso T; Fulcher AJ; Sriratana A; Ramm G; Horan KA; Gurung R; Wicking C; Smyth I; Mitchell CA
    J Cell Biol; 2017 Jan; 216(1):247-263. PubMed ID: 27998989
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of PtdIns(3,4,5)P3/Akt signalling by inositol polyphosphate 5-phosphatases.
    Eramo MJ; Mitchell CA
    Biochem Soc Trans; 2016 Feb; 44(1):240-52. PubMed ID: 26862211
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defective ciliogenesis in INPP5E-related Joubert syndrome.
    Hardee I; Soldatos A; Davids M; Vilboux T; Toro C; David KL; Ferreira CR; Nehrebecky M; Snow J; Thurm A; Heller T; Macnamara EF; Gunay-Aygun M; Zein WM; Gahl WA; Malicdan MCV
    Am J Med Genet A; 2017 Dec; 173(12):3231-3237. PubMed ID: 29052317
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathies.
    Conduit SE; Dyson JM; Mitchell CA
    FEBS Lett; 2012 Aug; 586(18):2846-57. PubMed ID: 22828281
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The type Ialpha inositol polyphosphate 4-phosphatase generates and terminates phosphoinositide 3-kinase signals on endosomes and the plasma membrane.
    Ivetac I; Munday AD; Kisseleva MV; Zhang XM; Luff S; Tiganis T; Whisstock JC; Rowe T; Majerus PW; Mitchell CA
    Mol Biol Cell; 2005 May; 16(5):2218-33. PubMed ID: 15716355
    [TBL] [Abstract][Full Text] [Related]  

  • 10. INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability.
    Plotnikova OV; Seo S; Cottle DL; Conduit S; Hakim S; Dyson JM; Mitchell CA; Smyth IM
    J Cell Sci; 2015 Jan; 128(2):364-72. PubMed ID: 25395580
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evidence of a role of inositol polyphosphate 5-phosphatase INPP5E in cilia formation in zebrafish.
    Luo N; Lu J; Sun Y
    Vision Res; 2012 Dec; 75():98-107. PubMed ID: 23022135
    [TBL] [Abstract][Full Text] [Related]  

  • 12. FRAGILE FIBER3, an Arabidopsis gene encoding a type II inositol polyphosphate 5-phosphatase, is required for secondary wall synthesis and actin organization in fiber cells.
    Zhong R; Burk DH; Morrison WH; Ye ZH
    Plant Cell; 2004 Dec; 16(12):3242-59. PubMed ID: 15539468
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphoinositide phosphatases: just as important as the kinases.
    Dyson JM; Fedele CG; Davies EM; Becanovic J; Mitchell CA
    Subcell Biochem; 2012; 58():215-79. PubMed ID: 22403078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of phosphoinositide signaling by the inositol polyphosphate 5-phosphatases.
    Astle MV; Seaton G; Davies EM; Fedele CG; Rahman P; Arsala L; Mitchell CA
    IUBMB Life; 2006 Aug; 58(8):451-6. PubMed ID: 16916781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphatidylinositol signalling reactions.
    Zhang X; Majerus PW
    Semin Cell Dev Biol; 1998 Apr; 9(2):153-60. PubMed ID: 9599410
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The diversity and possible functions of the inositol polyphosphate 5-phosphatases.
    Erneux C; Govaerts C; Communi D; Pesesse X
    Biochim Biophys Acta; 1998 Dec; 1436(1-2):185-99. PubMed ID: 9838104
    [TBL] [Abstract][Full Text] [Related]  

  • 17. INPP5E and Coordination of Signaling Networks in Cilia.
    Zhang R; Tang J; Li T; Zhou J; Pan W
    Front Mol Biosci; 2022; 9():885592. PubMed ID: 35463949
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A homozygous PDE6D mutation in Joubert syndrome impairs targeting of farnesylated INPP5E protein to the primary cilium.
    Thomas S; Wright KJ; Le Corre S; Micalizzi A; Romani M; Abhyankar A; Saada J; Perrault I; Amiel J; Litzler J; Filhol E; Elkhartoufi N; Kwong M; Casanova JL; Boddaert N; Baehr W; Lyonnet S; Munnich A; Burglen L; Chassaing N; Encha-Ravazi F; Vekemans M; Gleeson JG; Valente EM; Jackson PK; Drummond IA; Saunier S; Attié-Bitach T
    Hum Mutat; 2014 Jan; 35(1):137-46. PubMed ID: 24166846
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease.
    Ooms LM; Horan KA; Rahman P; Seaton G; Gurung R; Kethesparan DS; Mitchell CA
    Biochem J; 2009 Apr; 419(1):29-49. PubMed ID: 19272022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases.
    Ungewickell A; Hugge C; Kisseleva M; Chang SC; Zou J; Feng Y; Galyov EE; Wilson M; Majerus PW
    Proc Natl Acad Sci U S A; 2005 Dec; 102(52):18854-9. PubMed ID: 16365287
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.