178 related articles for article (PubMed ID: 19671752)
1. Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells.
Albert BJ; McPherson PA; O'Brien K; Czaicki NL; Destefino V; Osman S; Li M; Day BW; Grabowski PJ; Moore MJ; Vogt A; Koide K
Mol Cancer Ther; 2009 Aug; 8(8):2308-18. PubMed ID: 19671752
[TBL] [Abstract][Full Text] [Related]
2. Structural requirements for the antiproliferative activity of pre-mRNA splicing inhibitor FR901464.
Osman S; Albert BJ; Wang Y; Li M; Czaicki NL; Koide K
Chemistry; 2011 Jan; 17(3):895-904. PubMed ID: 21226105
[TBL] [Abstract][Full Text] [Related]
3. Total syntheses, fragmentation studies, and antitumor/antiproliferative activities of FR901464 and its low picomolar analogue.
Albert BJ; Sivaramakrishnan A; Naka T; Czaicki NL; Koide K
J Am Chem Soc; 2007 Mar; 129(9):2648-59. PubMed ID: 17279752
[TBL] [Abstract][Full Text] [Related]
4. Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma.
Sciarrillo R; Wojtuszkiewicz A; El Hassouni B; Funel N; Gandellini P; Lagerweij T; Buonamici S; Blijlevens M; Zeeuw van der Laan EA; Zaffaroni N; Deraco M; Kusamura S; Würdinger T; Peters GJ; Molthoff CFM; Jansen G; Kaspers GJL; Cloos J; Giovannetti E
EBioMedicine; 2019 Jan; 39():215-225. PubMed ID: 30581150
[TBL] [Abstract][Full Text] [Related]
5. Chemical Inhibition of Pre-mRNA Splicing in Living Saccharomyces cerevisiae.
Hansen SR; Nikolai BJ; Spreacker PJ; Carrocci TJ; Hoskins AA
Cell Chem Biol; 2019 Mar; 26(3):443-448.e3. PubMed ID: 30639260
[TBL] [Abstract][Full Text] [Related]
6. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
Kaida D; Motoyoshi H; Tashiro E; Nojima T; Hagiwara M; Ishigami K; Watanabe H; Kitahara T; Yoshida T; Nakajima H; Tani T; Horinouchi S; Yoshida M
Nat Chem Biol; 2007 Sep; 3(9):576-83. PubMed ID: 17643111
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and antiproliferative activity of a tetrahydrofuran analog of FR901464.
Pohorilets I; Beard JP; Driscoll JL; Schmitz JC; Koide K
Bioorg Med Chem Lett; 2024 May; 104():129739. PubMed ID: 38599298
[TBL] [Abstract][Full Text] [Related]
8. Antitumor compounds based on a natural product consensus pharmacophore.
Lagisetti C; Pourpak A; Jiang Q; Cui X; Goronga T; Morris SW; Webb TR
J Med Chem; 2008 Oct; 51(19):6220-4. PubMed ID: 18788726
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and Conformational Analysis of FR901464-Based RNA Splicing Modulators and Their Synergism in Drug-Resistant Cancers.
Beard JP; Bressin RK; Markaj PL; Schmitz JC; Koide K
J Med Chem; 2023 Nov; 66(21):14497-14512. PubMed ID: 37870431
[TBL] [Abstract][Full Text] [Related]
10. Structural Basis of Splicing Modulation by Antitumor Macrolide Compounds.
Cretu C; Agrawal AA; Cook A; Will CL; Fekkes P; Smith PG; Lührmann R; Larsen N; Buonamici S; Pena V
Mol Cell; 2018 Apr; 70(2):265-273.e8. PubMed ID: 29656923
[TBL] [Abstract][Full Text] [Related]
11. Coherence between cellular responses and in vitro splicing inhibition for the anti-tumor drug pladienolide B and its analogs.
Effenberger KA; Anderson DD; Bray WM; Prichard BE; Ma N; Adams MS; Ghosh AK; Jurica MS
J Biol Chem; 2014 Jan; 289(4):1938-47. PubMed ID: 24302718
[TBL] [Abstract][Full Text] [Related]
12. [Discovery of splicing inhibitors and its impact on drug development].
Kotake Y; Kaida D; Mizui Y; Yoshida M
Tanpakushitsu Kakusan Koso; 2008 Jan; 53(1):28-35. PubMed ID: 18186300
[No Abstract] [Full Text] [Related]
13. Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing.
Fan L; Lagisetti C; Edwards CC; Webb TR; Potter PM
ACS Chem Biol; 2011 Jun; 6(6):582-9. PubMed ID: 21344922
[TBL] [Abstract][Full Text] [Related]
14. Comparison of splicing factor 3b inhibitors in human cells.
Gao Y; Vogt A; Forsyth CJ; Koide K
Chembiochem; 2013 Jan; 14(1):49-52. PubMed ID: 23172726
[TBL] [Abstract][Full Text] [Related]
15. Therapy-induced stress response is associated with downregulation of pre-mRNA splicing in cancer cells.
Anufrieva KS; Shender VО; Arapidi GP; Pavlyukov MS; Shakhparonov MI; Shnaider PV; Butenko IO; Lagarkova MA; Govorun VM
Genome Med; 2018 Jun; 10(1):49. PubMed ID: 29950180
[TBL] [Abstract][Full Text] [Related]
16. Pre-mRNA splicing-modulatory pharmacophores: the total synthesis of herboxidiene, a pladienolide-herboxidiene hybrid analog and related derivatives.
Lagisetti C; Yermolina MV; Sharma LK; Palacios G; Prigaro BJ; Webb TR
ACS Chem Biol; 2014 Mar; 9(3):643-8. PubMed ID: 24377313
[TBL] [Abstract][Full Text] [Related]
17. Establishment of a monitoring system to detect inhibition of mRNA processing.
Fujita K; Okamura M; Nishimoto S; Kurihara T; Momma K; Miyamae Y; Kambe T; Nagao M; Narita H; Masuda S
Biosci Biotechnol Biochem; 2012; 76(6):1248-51. PubMed ID: 22790958
[TBL] [Abstract][Full Text] [Related]
18. Enantioselective total syntheses of FR901464 and spliceostatin A and evaluation of splicing activity of key derivatives.
Ghosh AK; Chen ZH; Effenberger KA; Jurica MS
J Org Chem; 2014 Jun; 79(12):5697-709. PubMed ID: 24873648
[TBL] [Abstract][Full Text] [Related]
19. Sudemycin K: A Synthetic Antitumor Splicing Inhibitor Variant with Improved Activity and Versatile Chemistry.
Makowski K; Vigevani L; Albericio F; Valcárcel J; Álvarez M
ACS Chem Biol; 2017 Jan; 12(1):163-173. PubMed ID: 28103691
[TBL] [Abstract][Full Text] [Related]
20. Genomics-guided discovery of thailanstatins A, B, and C As pre-mRNA splicing inhibitors and antiproliferative agents from Burkholderia thailandensis MSMB43.
Liu X; Biswas S; Berg MG; Antapli CM; Xie F; Wang Q; Tang MC; Tang GL; Zhang L; Dreyfuss G; Cheng YQ
J Nat Prod; 2013 Apr; 76(4):685-93. PubMed ID: 23517093
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]