BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 19671924)

  • 1. O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs.
    Klein AL; Berkaw MN; Buse MG; Ball LE
    Mol Cell Proteomics; 2009 Dec; 8(12):2733-45. PubMed ID: 19671924
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.
    Ball LE; Berkaw MN; Buse MG
    Mol Cell Proteomics; 2006 Feb; 5(2):313-23. PubMed ID: 16244361
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes.
    Whelan SA; Dias WB; Thiruneelakantapillai L; Lane MD; Hart GW
    J Biol Chem; 2010 Feb; 285(8):5204-11. PubMed ID: 20018868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes.
    Vosseller K; Wells L; Lane MD; Hart GW
    Proc Natl Acad Sci U S A; 2002 Apr; 99(8):5313-8. PubMed ID: 11959983
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.
    Sommerfeld MR; Metzger S; Stosik M; Tennagels N; Eckel J
    Biochemistry; 2004 May; 43(19):5888-901. PubMed ID: 15134463
    [TBL] [Abstract][Full Text] [Related]  

  • 6. O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes.
    Park SY; Ryu J; Lee W
    Exp Mol Med; 2005 Jun; 37(3):220-9. PubMed ID: 16000877
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of the amino acids 300-600 of IRS-2 as 14-3-3 binding region with the importance of IGF-1/insulin-regulated phosphorylation of Ser-573.
    Neukamm SS; Toth R; Morrice N; Campbell DG; Mackintosh C; Lehmann R; Haering HU; Schleicher ED; Weigert C
    PLoS One; 2012; 7(8):e43296. PubMed ID: 22912850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223.
    Luo M; Reyna S; Wang L; Yi Z; Carroll C; Dong LQ; Langlais P; Weintraub ST; Mandarino LJ
    Endocrinology; 2005 Oct; 146(10):4410-6. PubMed ID: 16020478
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM; Lorenzo M; Pons S; White MF; Benito M
    Mol Endocrinol; 1998 May; 12(5):688-97. PubMed ID: 9605931
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphatidylinositol 3'-kinase associates with an insulin receptor substrate-1 serine kinase distinct from its intrinsic serine kinase.
    Cengel KA; Kason RE; Freund GG
    Biochem J; 1998 Oct; 335 ( Pt 2)(Pt 2):397-404. PubMed ID: 9761740
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets.
    Alfaro JF; Gong CX; Monroe ME; Aldrich JT; Clauss TR; Purvine SO; Wang Z; Camp DG; Shabanowitz J; Stanley P; Hart GW; Hunt DF; Yang F; Smith RD
    Proc Natl Acad Sci U S A; 2012 May; 109(19):7280-5. PubMed ID: 22517741
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin-induced serine phosphorylation of IRS-2 via ERK1/2 and mTOR: studies on the function of Ser675 and Ser907.
    Fritsche L; Neukamm SS; Lehmann R; Kremmer E; Hennige AM; Hunder-Gugel A; Schenk M; Häring HU; Schleicher ED; Weigert C
    Am J Physiol Endocrinol Metab; 2011 May; 300(5):E824-36. PubMed ID: 21098738
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel post-translational modification in nerve terminals: O-linked N-acetylglucosamine phosphorylation.
    Graham ME; Thaysen-Andersen M; Bache N; Craft GE; Larsen MR; Packer NH; Robinson PJ
    J Proteome Res; 2011 Jun; 10(6):2725-33. PubMed ID: 21500857
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance.
    Kim JA; Yeh DC; Ver M; Li Y; Carranza A; Conrads TP; Veenstra TD; Harrington MA; Quon MJ
    J Biol Chem; 2005 Jun; 280(24):23173-83. PubMed ID: 15849359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. YMXM motifs and signaling by an insulin receptor substrate 1 molecule without tyrosine phosphorylation sites.
    Myers MG; Zhang Y; Aldaz GA; Grammer T; Glasheen EM; Yenush L; Wang LM; Sun XJ; Blenis J; Pierce JH; White MF
    Mol Cell Biol; 1996 Aug; 16(8):4147-55. PubMed ID: 8754813
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation.
    Yoneyama Y; Matsuo M; Take K; Kabuta T; Chida K; Hakuno F; Takahashi S
    Mol Cell Biol; 2013 May; 33(10):1991-2003. PubMed ID: 23478262
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S; Ito T; Wands JR
    J Biol Chem; 1996 Jun; 271(24):14610-6. PubMed ID: 8662827
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insulin-like growth factor-1 (IGF-1) receptor-insulin receptor substrate complexes in the uterus. Altered signaling response to estradiol in the IGF-1(m/m) mouse.
    Richards RG; Walker MP; Sebastian J; DiAugustine RP
    J Biol Chem; 1998 May; 273(19):11962-9. PubMed ID: 9565625
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of O-linked N-acetylglucosamine (O-GlcNAc)-modified osteoblast proteins by electron transfer dissociation tandem mass spectrometry reveals proteins critical for bone formation.
    Nagel AK; Schilling M; Comte-Walters S; Berkaw MN; Ball LE
    Mol Cell Proteomics; 2013 Apr; 12(4):945-55. PubMed ID: 23443134
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation.
    Greene MW; Sakaue H; Wang L; Alessi DR; Roth RA
    J Biol Chem; 2003 Mar; 278(10):8199-211. PubMed ID: 12510059
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.