166 related articles for article (PubMed ID: 19678643)
1. The nucleoside analogue D-carba T blocks HIV-1 reverse transcription.
Boyer PL; Vu BC; Ambrose Z; Julias JG; Warnecke S; Liao C; Meier C; Marquez VE; Hughes SH
J Med Chem; 2009 Sep; 52(17):5356-64. PubMed ID: 19678643
[TBL] [Abstract][Full Text] [Related]
2. The nucleoside analogs 4'C-methyl thymidine and 4'C-ethyl thymidine block DNA synthesis by wild-type HIV-1 RT and excision proficient NRTI resistant RT variants.
Boyer PL; Julias JG; Ambrose Z; Siddiqui MA; Marquez VE; Hughes SH
J Mol Biol; 2007 Aug; 371(4):873-82. PubMed ID: 17597154
[TBL] [Abstract][Full Text] [Related]
3. Mutational patterns in the HIV genome and cross-resistance following nucleoside and nucleotide analogue drug exposure.
Miller V; Larder BA
Antivir Ther; 2001; 6 Suppl 3():25-44. PubMed ID: 11678471
[TBL] [Abstract][Full Text] [Related]
4. Molecular mechanisms of HIV-1 resistance to nucleoside reverse transcriptase inhibitors (NRTIs).
Sluis-Cremer N; Arion D; Parniak MA
Cell Mol Life Sci; 2000 Sep; 57(10):1408-22. PubMed ID: 11078020
[TBL] [Abstract][Full Text] [Related]
5. Fixed conformation nucleoside analogs effectively inhibit excision-proficient HIV-1 reverse transcriptases.
Boyer PL; Julias JG; Marquez VE; Hughes SH
J Mol Biol; 2005 Jan; 345(3):441-50. PubMed ID: 15581889
[TBL] [Abstract][Full Text] [Related]
6. Stereoselective synthesis of D- and L-carbocyclic nucleosides by enzymatically catalyzed kinetic resolution.
Mahler M; Reichardt B; Hartjen P; van Lunzen J; Meier C
Chemistry; 2012 Aug; 18(35):11046-62. PubMed ID: 22829408
[TBL] [Abstract][Full Text] [Related]
7. HIV-1 resistance profile of the novel nucleoside reverse transcriptase inhibitor beta-D-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine (Reverset).
Geleziunas R; Gallagher K; Zhang H; Bacheler L; Garber S; Wu JT; Shi G; Otto MJ; Schinazi RF; Erickson-Viitanen S
Antivir Chem Chemother; 2003 Jan; 14(1):49-59. PubMed ID: 12790516
[TBL] [Abstract][Full Text] [Related]
8. Nucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase.
Sharma PL; Nurpeisov V; Hernandez-Santiago B; Beltran T; Schinazi RF
Curr Top Med Chem; 2004; 4(9):895-919. PubMed ID: 15134548
[TBL] [Abstract][Full Text] [Related]
9. Amino acid residues in HIV-2 reverse transcriptase that restrict the development of nucleoside analogue resistance through the excision pathway.
Álvarez M; Nevot M; Mendieta J; Martínez MA; Menéndez-Arias L
J Biol Chem; 2018 Feb; 293(7):2247-2259. PubMed ID: 29275329
[TBL] [Abstract][Full Text] [Related]
10. A structural frame for understanding the role of thymidine analogue resistance mutations in resistance to zidovudine and other nucleoside analogues.
Menéndez-Arias L
Antivir Ther; 2011; 16(7):943-6. PubMed ID: 22024508
[TBL] [Abstract][Full Text] [Related]
11. Structure, Synthesis and Inhibition Mechanism of Nucleoside Analogues as HIV-1 Reverse Transcriptase Inhibitors (NRTIs).
Yoshida Y; Honma M; Kimura Y; Abe H
ChemMedChem; 2021 Mar; 16(5):743-766. PubMed ID: 33230979
[TBL] [Abstract][Full Text] [Related]
12. Nucleoside analog resistance caused by insertions in the fingers of human immunodeficiency virus type 1 reverse transcriptase involves ATP-mediated excision.
Boyer PL; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2002 Sep; 76(18):9143-51. PubMed ID: 12186898
[TBL] [Abstract][Full Text] [Related]
13. Mechanisms of resistance to nucleoside analogue inhibitors of HIV-1 reverse transcriptase.
Menéndez-Arias L
Virus Res; 2008 Jun; 134(1-2):124-46. PubMed ID: 18272247
[TBL] [Abstract][Full Text] [Related]
14. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
[TBL] [Abstract][Full Text] [Related]
15. Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.
White KL; Chen JM; Margot NA; Wrin T; Petropoulos CJ; Naeger LK; Swaminathan S; Miller MD
Antimicrob Agents Chemother; 2004 Mar; 48(3):992-1003. PubMed ID: 14982794
[TBL] [Abstract][Full Text] [Related]
16. HIV-1 polymerase inhibition by nucleoside analogs: cellular- and kinetic parameters of efficacy, susceptibility and resistance selection.
von Kleist M; Metzner P; Marquet R; Schütte C
PLoS Comput Biol; 2012 Jan; 8(1):e1002359. PubMed ID: 22275860
[TBL] [Abstract][Full Text] [Related]
17. Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-Ethynyl-2-fluoro-2'-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor.
Michailidis E; Marchand B; Kodama EN; Singh K; Matsuoka M; Kirby KA; Ryan EM; Sawani AM; Nagy E; Ashida N; Mitsuya H; Parniak MA; Sarafianos SG
J Biol Chem; 2009 Dec; 284(51):35681-91. PubMed ID: 19837673
[TBL] [Abstract][Full Text] [Related]
18. "Second generation" of TSAO compounds directed against HIV-1 TSAO-resistant strains.
Lobatón E; Velázquez S; Pérez-Pérez MJ; Jimeno ML; San-Félix A; De Clercq E; Balzarini J; Camarasa MJ
Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):707-10. PubMed ID: 11563097
[TBL] [Abstract][Full Text] [Related]
19. Structural determinants and molecular mechanisms for the resistance of HIV-1 RT to nucleoside analogues.
Deval J; Courcambeck J; Selmi B; Boretto J; Canard B
Curr Drug Metab; 2004 Aug; 5(4):305-16. PubMed ID: 15320702
[TBL] [Abstract][Full Text] [Related]
20. The emergence of different resistance mechanisms toward nucleoside inhibitors is explained by the properties of the wild type HIV-1 reverse transcriptase.
Isel C; Ehresmann C; Walter P; Ehresmann B; Marquet R
J Biol Chem; 2001 Dec; 276(52):48725-32. PubMed ID: 11668180
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
