These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK. Babchia N; Calipel A; Mouriaux F; Faussat AM; Mascarelli F Invest Ophthalmol Vis Sci; 2010 Jan; 51(1):421-9. PubMed ID: 19661225 [TBL] [Abstract][Full Text] [Related]
3. Phosphatidylinositol-3-kinase/Akt signaling pathway and kidney cancer, and the therapeutic potential of phosphatidylinositol-3-kinase/Akt inhibitors. Porta C; Figlin RA J Urol; 2009 Dec; 182(6):2569-77. PubMed ID: 19836781 [TBL] [Abstract][Full Text] [Related]
4. The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients. Martelli AM; Evangelisti C; Chiarini F; McCubrey JA Oncotarget; 2010 Jun; 1(2):89-103. PubMed ID: 20671809 [TBL] [Abstract][Full Text] [Related]
6. WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant. Li T; Wang J; Wang X; Yang N; Chen SM; Tong LJ; Yang CH; Meng LH; Ding J J Pharmacol Exp Ther; 2010 Sep; 334(3):830-8. PubMed ID: 20522531 [TBL] [Abstract][Full Text] [Related]
7. Targeting the PI3K-AKT-mTOR pathway: progress, pitfalls, and promises. Yap TA; Garrett MD; Walton MI; Raynaud F; de Bono JS; Workman P Curr Opin Pharmacol; 2008 Aug; 8(4):393-412. PubMed ID: 18721898 [TBL] [Abstract][Full Text] [Related]
8. Handicapping the race to develop inhibitors of the phosphoinositide 3-kinase/Akt/mammalian target of rapamycin pathway. Granville CA; Memmott RM; Gills JJ; Dennis PA Clin Cancer Res; 2006 Feb; 12(3 Pt 1):679-89. PubMed ID: 16467077 [TBL] [Abstract][Full Text] [Related]
9. Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling. van de Laar L; Buitenhuis M; Wensveen FM; Janssen HL; Coffer PJ; Woltman AM J Immunol; 2010 Jun; 184(12):6600-11. PubMed ID: 20488790 [TBL] [Abstract][Full Text] [Related]
10. Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugates. Ayral-Kaloustian S; Gu J; Lucas J; Cinque M; Gaydos C; Zask A; Chaudhary I; Wang J; Di L; Young M; Ruppen M; Mansour TS; Gibbons JJ; Yu K J Med Chem; 2010 Jan; 53(1):452-9. PubMed ID: 19928864 [TBL] [Abstract][Full Text] [Related]
11. [Topics in mTOR pathway and its inhibitors]. Dreyer C; Sablin MP; Faivre S; Raymond E Bull Cancer; 2009 Jan; 96(1):87-94. PubMed ID: 19211363 [TBL] [Abstract][Full Text] [Related]
12. Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease. Zitzmann K; Rüden Jv; Brand S; Göke B; Lichtl J; Spöttl G; Auernhammer CJ Cancer Lett; 2010 Sep; 295(1):100-9. PubMed ID: 20356670 [TBL] [Abstract][Full Text] [Related]
13. Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer. Kim D; Cheng GZ; Lindsley CW; Yang H; Cheng JQ Curr Opin Investig Drugs; 2005 Dec; 6(12):1250-8. PubMed ID: 16370391 [TBL] [Abstract][Full Text] [Related]
14. New inhibitors of the mammalian target of rapamycin signaling pathway for cancer. Albert S; Serova M; Dreyer C; Sablin MP; Faivre S; Raymond E Expert Opin Investig Drugs; 2010 Aug; 19(8):919-30. PubMed ID: 20569080 [TBL] [Abstract][Full Text] [Related]
16. Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside. Martelli AM; Tazzari PL; Evangelisti C; Chiarini F; Blalock WL; Billi AM; Manzoli L; McCubrey JA; Cocco L Curr Med Chem; 2007; 14(19):2009-23. PubMed ID: 17691943 [TBL] [Abstract][Full Text] [Related]
17. The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation. Follo MY; Mongiorgi S; Bosi C; Cappellini A; Finelli C; Chiarini F; Papa V; Libra M; Martinelli G; Cocco L; Martelli AM Cancer Res; 2007 May; 67(9):4287-94. PubMed ID: 17483341 [TBL] [Abstract][Full Text] [Related]
18. Targeting mTOR signaling in lung cancer. Marinov M; Fischer B; Arcaro A Crit Rev Oncol Hematol; 2007 Aug; 63(2):172-82. PubMed ID: 17540577 [TBL] [Abstract][Full Text] [Related]