195 related articles for article (PubMed ID: 19682504)
1. Hsp90 transcriptionally and post-translationally regulates the expression of NDRG1 and maintains the stability of its modifying kinase GSK3beta.
Banz VM; Medová M; Keogh A; Furer C; Zimmer Y; Candinas D; Stroka D
Biochim Biophys Acta; 2009 Oct; 1793(10):1597-603. PubMed ID: 19682504
[TBL] [Abstract][Full Text] [Related]
2. NDRG1 promotes growth of hepatocellular carcinoma cells by directly interacting with GSK-3β and Nur77 to prevent β-catenin degradation.
Lu WJ; Chua MS; Wei W; So SK
Oncotarget; 2015 Oct; 6(30):29847-59. PubMed ID: 26359353
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death.
Georgakis GV; Li Y; Rassidakis GZ; Martinez-Valdez H; Medeiros LJ; Younes A
Clin Cancer Res; 2006 Jan; 12(2):584-90. PubMed ID: 16428504
[TBL] [Abstract][Full Text] [Related]
4. Heat shock protein 90 (Hsp90) regulates the stability of transforming growth factor beta-activated kinase 1 (TAK1) in interleukin-1beta-induced cell signaling.
Shi L; Zhang Z; Fang S; Xu J; Liu J; Shen J; Fang F; Luo L; Yin Z
Mol Immunol; 2009 Feb; 46(4):541-50. PubMed ID: 18950863
[TBL] [Abstract][Full Text] [Related]
5. Mutational Analysis of Glycogen Synthase Kinase 3β Protein Kinase Together with Kinome-Wide Binding and Stability Studies Suggests Context-Dependent Recognition of Kinases by the Chaperone Heat Shock Protein 90.
Jin J; Tian R; Pasculescu A; Dai AY; Williton K; Taylor L; Savitski MM; Bantscheff M; Woodgett JR; Pawson T; Colwill K
Mol Cell Biol; 2016 Jan; 36(6):1007-18. PubMed ID: 26755559
[TBL] [Abstract][Full Text] [Related]
6. Heat shock protein 90 regulates the stability of MEKK3 in HEK293 cells.
Fang S; Fu J; Yuan X; Han C; Shi L; Xin Y; Luo L; Yin Z
Cell Immunol; 2009; 259(1):49-55. PubMed ID: 19560753
[TBL] [Abstract][Full Text] [Related]
7. HSP27 expression levels are associated with the sensitivity of hepatocellular carcinoma cells to 17-allylamino-17-demethoxygeldanamycin.
Cui Y; Wu W; Zhou Y; Xie Q; Liu T; Jin J; Liu K
Future Oncol; 2013 Mar; 9(3):411-8. PubMed ID: 23469976
[TBL] [Abstract][Full Text] [Related]
8. Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells.
Yoshikawa N; Nemoto T; Satoh S; Maruta T; Yanagita T; Chosa E; Wada A
Neurochem Int; 2010 Jan; 56(1):42-50. PubMed ID: 19737590
[TBL] [Abstract][Full Text] [Related]
9. Bidirectional Regulation between NDRG1 and GSK3β Controls Tumor Growth and Is Targeted by Differentiation Inducing Factor-1 in Glioblastoma.
Ito H; Watari K; Shibata T; Miyamoto T; Murakami Y; Nakahara Y; Izumi H; Wakimoto H; Kuwano M; Abe T; Ono M
Cancer Res; 2020 Jan; 80(2):234-248. PubMed ID: 31723002
[TBL] [Abstract][Full Text] [Related]
10. The neuroblastoma tumour-suppressor TrkAI and its oncogenic alternative TrkAIII splice variant exhibit geldanamycin-sensitive interactions with Hsp90 in human neuroblastoma cells.
Farina AR; Tacconelli A; Cappabianca L; Cea G; Chioda A; Romanelli A; Pensato S; Pedone C; Gulino A; Mackay AR
Oncogene; 2009 Nov; 28(46):4075-94. PubMed ID: 19734938
[TBL] [Abstract][Full Text] [Related]
11. Two mechanisms involving the autophagic and proteasomal pathways process the metastasis suppressor protein, N-myc downstream regulated gene 1.
Sahni S; Park KC; Kovacevic Z; Richardson DR
Biochim Biophys Acta Mol Basis Dis; 2019 Jun; 1865(6):1361-1378. PubMed ID: 30763642
[TBL] [Abstract][Full Text] [Related]
12. Blocking the chaperone kinome pathway: mechanistic insights into a novel dual inhibition approach for supra-additive suppression of malignant tumors.
Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
Biochem Biophys Res Commun; 2011 Jan; 404(1):498-503. PubMed ID: 21144839
[TBL] [Abstract][Full Text] [Related]
13. Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation.
Crèvecoeur J; Merville MP; Piette J; Gloire G
Biochem Pharmacol; 2008 Jun; 75(11):2183-91. PubMed ID: 18455150
[TBL] [Abstract][Full Text] [Related]
14. Oncogenic MNK signalling regulates the metastasis suppressor NDRG1.
Tian S; Wang X; Proud CG
Oncotarget; 2017 Jul; 8(28):46121-46135. PubMed ID: 28545025
[TBL] [Abstract][Full Text] [Related]
15. Client Proteins and Small Molecule Inhibitors Display Distinct Binding Preferences for Constitutive and Stress-Induced HSP90 Isoforms and Their Conformationally Restricted Mutants.
Prince TL; Kijima T; Tatokoro M; Lee S; Tsutsumi S; Yim K; Rivas C; Alarcon S; Schwartz H; Khamit-Kush K; Scroggins BT; Beebe K; Trepel JB; Neckers L
PLoS One; 2015; 10(10):e0141786. PubMed ID: 26517842
[TBL] [Abstract][Full Text] [Related]
16. FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.
Yao Q; Nishiuchi R; Li Q; Kumar AR; Hudson WA; Kersey JH
Clin Cancer Res; 2003 Oct; 9(12):4483-93. PubMed ID: 14555522
[TBL] [Abstract][Full Text] [Related]
17. Hsp90 regulates p50(cdc37) function during the biogenesis of the activeconformation of the heme-regulated eIF2 alpha kinase.
Shao J; Grammatikakis N; Scroggins BT; Uma S; Huang W; Chen JJ; Hartson SD; Matts RL
J Biol Chem; 2001 Jan; 276(1):206-14. PubMed ID: 11036079
[TBL] [Abstract][Full Text] [Related]
18. Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.
Kang SA; Cho HS; Yoon JB; Chung IK; Lee ST
Biochem J; 2012 Oct; 447(2):313-20. PubMed ID: 22849407
[TBL] [Abstract][Full Text] [Related]
19. N-myc downstream regulated gene1/Cap43 overexpression suppresses tumor growth by hepatic cancer cells through cell cycle arrest at the G0/G1 phase.
Akiba J; Murakami Y; Noda M; Watari K; Ogasawara S; Yoshida T; Kawahara A; Sanada S; Yasumoto M; Yamaguchi R; Kage M; Kuwano M; Ono M; Yano H
Cancer Lett; 2011 Nov; 310(1):25-34. PubMed ID: 21775055
[TBL] [Abstract][Full Text] [Related]
20. Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.
Murray JT; Campbell DG; Morrice N; Auld GC; Shpiro N; Marquez R; Peggie M; Bain J; Bloomberg GB; Grahammer F; Lang F; Wulff P; Kuhl D; Cohen P
Biochem J; 2004 Dec; 384(Pt 3):477-88. PubMed ID: 15461589
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
