429 related articles for article (PubMed ID: 19688288)
1. The synthesized 2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-one (CHM-1) promoted G2/M arrest through inhibition of CDK1 and induced apoptosis through the mitochondrial-dependent pathway in CT-26 murine colorectal adenocarcinoma cells.
Chou LC; Yang JS; Huang LJ; Wu HC; Lu CC; Chiang JH; Chen KT; Kuo SC; Chung JG
J Gastroenterol; 2009; 44(10):1055-63. PubMed ID: 19688288
[TBL] [Abstract][Full Text] [Related]
2. The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells.
Huang SM; Yang JS; Tsai SC; Chen MH; Hsu MH; Lin HY; Chou LC; Chinag JH; Lee KH; Huang LJ; Kuo SC
Int J Oncol; 2011 May; 38(5):1357-64. PubMed ID: 21344160
[TBL] [Abstract][Full Text] [Related]
3. CHM-1, a novel synthetic quinolone with potent and selective antimitotic antitumor activity against human hepatocellular carcinoma in vitro and in vivo.
Wang SW; Pan SL; Huang YC; Guh JH; Chiang PC; Huang DY; Kuo SC; Lee KH; Teng CM
Mol Cancer Ther; 2008 Feb; 7(2):350-60. PubMed ID: 18281518
[TBL] [Abstract][Full Text] [Related]
4. Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
Wu W; Ye H; Wan L; Han X; Wang G; Hu J; Tang M; Duan X; Fan Y; He S; Huang L; Pei H; Wang X; Li X; Xie C; Zhang R; Yuan Z; Mao Y; Wei Y; Chen L
Carcinogenesis; 2013 Jul; 34(7):1636-43. PubMed ID: 23471882
[TBL] [Abstract][Full Text] [Related]
5. Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways.
Huang WW; Ko SW; Tsai HY; Chung JG; Chiang JH; Chen KT; Chen YC; Chen HY; Chen YF; Yang JS
Int J Oncol; 2011 Apr; 38(4):1067-73. PubMed ID: 21271215
[TBL] [Abstract][Full Text] [Related]
6. SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo.
Xia Y; Lei Q; Zhu Y; Ye T; Wang N; Li G; Shi X; Liu Y; Shao B; Yin T; Zhao L; Wu W; Song X; Xiong Y; Wei Y; Yu L
Cancer Lett; 2014 Dec; 355(2):297-309. PubMed ID: 25301449
[TBL] [Abstract][Full Text] [Related]
7. Anti-tumor potential of 15,16-dihydrotanshinone I against breast adenocarcinoma through inducing G1 arrest and apoptosis.
Tsai SL; Suk FM; Wang CI; Liu DZ; Hou WC; Lin PJ; Hung LF; Liang YC
Biochem Pharmacol; 2007 Dec; 74(11):1575-86. PubMed ID: 17869226
[TBL] [Abstract][Full Text] [Related]
8. Induction of G2/M arrest and apoptosis by water extract of Strychni Semen in human gastric carcinoma AGS cells.
Lee SM; Kwon JI; Choi YH; Eom HS; Chi GY
Phytother Res; 2008 Jun; 22(6):752-8. PubMed ID: 18446845
[TBL] [Abstract][Full Text] [Related]
9. The quinolone derivative CHM-1 inhibits murine WEHI-3 leukemia in BALB/c mice in vivo.
Lai TY; Yang JS; Wu PP; Huang WW; Kuo SC; Ma CY; Gibson Wood W; Chung JG
Leuk Lymphoma; 2010 Nov; 51(11):2098-102. PubMed ID: 20846096
[TBL] [Abstract][Full Text] [Related]
10. Induction of mitotic arrest and apoptosis by a novel synthetic quinolone analogue, CWC-8, via intrinsic and extrinsic apoptotic pathways in human osteogenic sarcoma U-2 OS cells.
Chang YH; Yang JS; Kuo SC; Chung JG
Anticancer Res; 2009 Aug; 29(8):3139-48. PubMed ID: 19661327
[TBL] [Abstract][Full Text] [Related]
11. Novel quinolone CHM-1 induces apoptosis and inhibits metastasis in a human osterogenic sarcoma cell line.
Hsu SC; Yang JS; Kuo CL; Lo C; Lin JP; Hsia TC; Lin JJ; Lai KC; Kuo HM; Huang LJ; Kuo SC; Wood WG; Chung JG
J Orthop Res; 2009 Dec; 27(12):1637-44. PubMed ID: 19557855
[TBL] [Abstract][Full Text] [Related]
12. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
Xiao D; Johnson CS; Trump DL; Singh SV
Mol Cancer Ther; 2004 May; 3(5):567-75. PubMed ID: 15141014
[TBL] [Abstract][Full Text] [Related]
13. Delicaflavone induces apoptosis via mitochondrial pathway accompanying G2/M cycle arrest and inhibition of MAPK signaling cascades in cervical cancer HeLa cells.
Yao W; Lin Z; Wang G; Li S; Chen B; Sui Y; Huang J; Liu Q; Shi P; Lin X; Liu Q; Yao H
Phytomedicine; 2019 Sep; 62():152973. PubMed ID: 31177019
[TBL] [Abstract][Full Text] [Related]
14. CHM-1 induces apoptosis via p38-mediated upregulation of DR5 expression in human ovarian cancer SKOV3 cells.
Lee JC; Chou LC; Huang CH; Chung JG; Huang LJ; Lee KH; Hung MC; Way TD; Kuo SC
Eur J Pharmacol; 2011 Nov; 670(1):96-104. PubMed ID: 21907193
[TBL] [Abstract][Full Text] [Related]
15. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
Huang SH; Wu LW; Huang AC; Yu CC; Lien JC; Huang YP; Yang JS; Yang JH; Hsiao YP; Wood WG; Yu CS; Chung JG
J Agric Food Chem; 2012 Jan; 60(2):665-75. PubMed ID: 22148415
[TBL] [Abstract][Full Text] [Related]
16. Smh-3 induces G(2)/M arrest and apoptosis through calcium‑mediated endoplasmic reticulum stress and mitochondrial signaling in human hepatocellular carcinoma Hep3B cells.
Liu CY; Yang JS; Huang SM; Chiang JH; Chen MH; Huang LJ; Ha HY; Fushiya S; Kuo SC
Oncol Rep; 2013 Feb; 29(2):751-62. PubMed ID: 23233035
[TBL] [Abstract][Full Text] [Related]
17. A novel synthetic 2-(3-methoxyphenyl)-6,7-methylenedioxoquinolin-4-one arrests the G2/M phase arrest via Cdc25c and induces apoptosis through caspase- and mitochondria-dependent pathways in TSGH8301 human bladder cancer cells.
Hsu SC; Yu CC; Yang JS; Lai KC; Wu SH; Lin JJ; Kuo JH; Yang ST; Huang CC; Kuo SC; Chung JG
Int J Oncol; 2012 Mar; 40(3):731-8. PubMed ID: 22021033
[TBL] [Abstract][Full Text] [Related]
18. NCPMF-60 induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells.
Dai QS; Liu W; Wang XB; Lu N; Gong DD; Kong LY; Guo QL
Anticancer Drugs; 2011 Jan; 22(1):46-57. PubMed ID: 20948430
[TBL] [Abstract][Full Text] [Related]
19. [Induction of G2 /M phase arrest and apoptosis of MCF-7 cells by novel benzofuran lignan via suppressing cell cycle proteins].
Yang H; Cai YC; Pang JY; Li YQ; Zeng ZL; Xu ZL; Xian LJ
Yao Xue Xue Bao; 2008 Feb; 43(2):138-44. PubMed ID: 18507339
[TBL] [Abstract][Full Text] [Related]
20. DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells.
Qiao F; Zuo D; Wang H; Li Z; Qi H; Zhang W; Wu Y
Biol Pharm Bull; 2013; 36(2):193-201. PubMed ID: 23370351
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]