BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 19689938)

  • 1. [Utilization of Werner syndrome mouse model in studying premature aging and tumor].
    Jia ST; Yang SH; Luo Y
    Yi Chuan; 2009 Aug; 31(8):785-90. PubMed ID: 19689938
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.
    Cheng WH; Muftuoglu M; Bohr VA
    Exp Gerontol; 2007 Sep; 42(9):871-8. PubMed ID: 17587522
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Telomere ResQue and preservation--roles for the Werner syndrome protein and other RecQ helicases.
    Opresko PL
    Mech Ageing Dev; 2008; 129(1-2):79-90. PubMed ID: 18054793
    [TBL] [Abstract][Full Text] [Related]  

  • 4. WRN at telomeres: implications for aging and cancer.
    Multani AS; Chang S
    J Cell Sci; 2007 Mar; 120(Pt 5):713-21. PubMed ID: 17314245
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of Werner syndrome gene product helicase in carcinogenesis and in resistance to genotoxins by cancer cells.
    Futami K; Ishikawa Y; Goto M; Furuichi Y; Sugimoto M
    Cancer Sci; 2008 May; 99(5):843-8. PubMed ID: 18312465
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Werner syndrome (WRN) gene variants and their association with altered function and age-associated diseases.
    Lebel M; Monnat RJ
    Ageing Res Rev; 2018 Jan; 41():82-97. PubMed ID: 29146545
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Werner syndrome. A model for the study of human aging.
    Nehlin JO; Skovgaard GL; Bohr VA
    Ann N Y Acad Sci; 2000 Jun; 908():167-79. PubMed ID: 10911957
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions.
    Oshima J; Sidorova JM; Monnat RJ
    Ageing Res Rev; 2017 Jan; 33():105-114. PubMed ID: 26993153
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomere dysfunction as a cause of genomic instability in Werner syndrome.
    Crabbe L; Jauch A; Naeger CM; Holtgreve-Grez H; Karlseder J
    Proc Natl Acad Sci U S A; 2007 Feb; 104(7):2205-10. PubMed ID: 17284601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A mouse model of Werner Syndrome: what can it tell us about aging and cancer?
    Chang S
    Int J Biochem Cell Biol; 2005 May; 37(5):991-9. PubMed ID: 15743673
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome.
    Hui CW; St-Pierre MK; Detuncq J; Aumailley L; Dubois MJ; Couture V; Skuk D; Marette A; Tremblay JP; Lebel M; Tremblay MÈ
    Brain Behav Immun; 2018 Oct; 73():450-469. PubMed ID: 29908963
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
    Agrelo R; Cheng WH; Setien F; Ropero S; Espada J; Fraga MF; Herranz M; Paz MF; Sanchez-Cespedes M; Artiga MJ; Guerrero D; Castells A; von Kobbe C; Bohr VA; Esteller M
    Proc Natl Acad Sci U S A; 2006 Jun; 103(23):8822-7. PubMed ID: 16723399
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis.
    Muftuoglu M; Oshima J; von Kobbe C; Cheng WH; Leistritz DF; Bohr VA
    Hum Genet; 2008 Nov; 124(4):369-77. PubMed ID: 18810497
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Divergent cellular phenotypes of human and mouse cells lacking the Werner syndrome RecQ helicase.
    Dhillon KK; Sidorova JM; Albertson TM; Anderson JB; Ladiges WC; Rabinovitch PS; Preston BD; Monnat RJ
    DNA Repair (Amst); 2010 Jan; 9(1):11-22. PubMed ID: 19896421
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.
    Turaga RV; Paquet ER; Sild M; Vignard J; Garand C; Johnson FB; Masson JY; Lebel M
    Cell Cycle; 2009 Jul; 8(13):2080-92. PubMed ID: 19502800
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Werner syndrome: a changing pattern of clinical manifestations in Japan (1917~2008).
    Goto M; Ishikawa Y; Sugimoto M; Furuichi Y
    Biosci Trends; 2013 Feb; 7(1):13-22. PubMed ID: 23524889
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway.
    Laud PR; Multani AS; Bailey SM; Wu L; Ma J; Kingsley C; Lebel M; Pathak S; DePinho RA; Chang S
    Genes Dev; 2005 Nov; 19(21):2560-70. PubMed ID: 16264192
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.
    Yamamoto ML; Reliene R; Oshima J; Schiestl RH
    Mutat Res; 2008 Sep; 644(1-2):11-6. PubMed ID: 18639560
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.
    Shimamoto A; Kagawa H; Zensho K; Sera Y; Kazuki Y; Osaki M; Oshimura M; Ishigaki Y; Hamasaki K; Kodama Y; Yuasa S; Fukuda K; Hirashima K; Seimiya H; Koyama H; Shimizu T; Takemoto M; Yokote K; Goto M; Tahara H
    PLoS One; 2014; 9(11):e112900. PubMed ID: 25390333
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (review).
    Sugimoto M
    Int J Mol Med; 2014 Feb; 33(2):247-53. PubMed ID: 24356923
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.