170 related articles for article (PubMed ID: 19691069)
1. Factors affecting DNA-DNA interstrand cross-links in the antiparallel 3'-3' sense: a comparison with the 5'-5' directional isomer.
Ruhayel RA; Moniodis JJ; Yang X; Kasparkova J; Brabec V; Berners-Price SJ; Farrell NP
Chemistry; 2009 Sep; 15(37):9365-74. PubMed ID: 19691069
[TBL] [Abstract][Full Text] [Related]
2. Long range 1,4 and 1,6-interstrand cross-links formed by a trinuclear platinum complex. Minor groove preassociation affects kinetics and mechanism of cross-link formation as well as adduct structure.
Hegmans A; Berners-Price SJ; Davies MS; Thomas DS; Humphreys AS; Farrell N
J Am Chem Soc; 2004 Feb; 126(7):2166-80. PubMed ID: 14971952
[TBL] [Abstract][Full Text] [Related]
3. Chimeric platinum-polyamines and DNA binding. Kinetics of DNA interstrand cross-link formation by dinuclear platinum complexes with polyamine linkers.
Ruhayel RA; Langner JS; Oke MJ; Berners-Price SJ; Zgani I; Farrell NP
J Am Chem Soc; 2012 Apr; 134(16):7135-46. PubMed ID: 22443454
[TBL] [Abstract][Full Text] [Related]
4. Effects of geometric isomerism and anions on the kinetics and mechanism of the stepwise formation of long-range DNA interstrand cross-links by dinuclear platinum antitumor complexes.
Zhang J; Thomas DS; Berners-Price SJ; Farrell N
Chemistry; 2008; 14(21):6391-405. PubMed ID: 18537208
[TBL] [Abstract][Full Text] [Related]
5. Competitive reactions of interstrand and intrastrand DNA-Pt adducts: A dinuclear-platinum complex preferentially forms a 1,4-interstrand cross-link rather than a 1,2 intrastrand cross-link on binding to a GG 14-mer duplex.
Berners-Price SJ; Davies MS; Cox JW; Thomas DS; Farrell N
Chemistry; 2003 Feb; 9(3):713-25. PubMed ID: 12569464
[TBL] [Abstract][Full Text] [Related]
6. Kinetic analysis of the stepwise formation of a long-range DNA interstrand cross-link by a dinuclear platinum antitumor complex: evidence for aquated intermediates and formation of both kinetically and thermodynamically controlled conformers.
Cox JW; Berners-Price SJ; Davies MS; Qu Y; Farrell N
J Am Chem Soc; 2001 Feb; 123(7):1316-26. PubMed ID: 11456703
[TBL] [Abstract][Full Text] [Related]
7. Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes.
Qu Y; Scarsdale NJ; Tran MC; Farrell N
J Inorg Biochem; 2004 Oct; 98(10):1585-90. PubMed ID: 15458820
[TBL] [Abstract][Full Text] [Related]
8. Cooperative effects in long-range 1,4 DNA-DNA interstrand cross-links formed by polynuclear platinum complexes: an unexpected syn orientation of adenine bases outside the binding sites.
Qu Y; Scarsdale NJ; Tran MC; Farrell NP
J Biol Inorg Chem; 2003 Jan; 8(1-2):19-28. PubMed ID: 12459895
[TBL] [Abstract][Full Text] [Related]
9. DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent.
Brabec V; Kaspárková J; Vrána O; Nováková O; Cox JW; Qu Y; Farrell N
Biochemistry; 1999 May; 38(21):6781-90. PubMed ID: 10346899
[TBL] [Abstract][Full Text] [Related]
10. Competitive formation of both long-range 5'-5' and short-range antiparallel 3'-3' DNA interstrand cross-links by a trinuclear platinum complex on binding to a 10-mer duplex.
Ruhayel RA; Berners-Price SJ; Farrell NP
Dalton Trans; 2013 Mar; 42(9):3181-7. PubMed ID: 23165925
[TBL] [Abstract][Full Text] [Related]
11. Structural consequences of a 3'-->3' DNA interstrand cross-link by a trinuclear platinum complex: unique formation of two such cross-links in a 10-mer duplex.
Qu Y; Tran MC; Farrell NP
J Biol Inorg Chem; 2009 Aug; 14(6):969-77. PubMed ID: 19415349
[TBL] [Abstract][Full Text] [Related]
12. The trans influence in the modulation of platinum anticancer agent biology: the effect of nitrite leaving group on aquation, reactions with S-nucleophiles and DNA binding of dinuclear and trinuclear compounds.
Montero EI; Zhang J; Moniodis JJ; Berners-Price SJ; Farrell NP
Chemistry; 2010 Aug; 16(30):9175-85. PubMed ID: 20589847
[TBL] [Abstract][Full Text] [Related]
13. DNA interstrand cross-links of an antitumor trinuclear platinum(II) complex: thermodynamic analysis and chemical probing.
Malina J; Farrell NP; Brabec V
Chem Asian J; 2011 Jun; 6(6):1566-74. PubMed ID: 21557487
[TBL] [Abstract][Full Text] [Related]
14. Effects of geometric isomerism in dinuclear antitumor platinum complexes on their interactions with N-acetyl-L-methionine.
Oehlsen ME; Hegmans A; Qu Y; Farrell N
J Biol Inorg Chem; 2005 Aug; 10(5):433-42. PubMed ID: 16091934
[TBL] [Abstract][Full Text] [Related]
15. Reaction of polynuclear platinum antitumor compounds with reduced glutathione studied by multinuclear (1H, 1H-15N gradient heteronuclear single-quantum coherence, and 195Pt) NMR spectroscopy.
Oehlsen ME; Qu Y; Farrell N
Inorg Chem; 2003 Sep; 42(18):5498-506. PubMed ID: 12950196
[TBL] [Abstract][Full Text] [Related]
16. A comparison of DNA binding profiles of dinuclear platinum compounds with polyamine linkers and the trinuclear platinum phase II clinical agent BBR3464.
McGregor TD; Hegmans A; Kaspárková J; Neplechová K; Nováková O; Penazová H; Vrána O; Brabec V; Farrell N
J Biol Inorg Chem; 2002 Apr; 7(4-5):397-404. PubMed ID: 11941497
[TBL] [Abstract][Full Text] [Related]
17. Trifunctional dinuclear platinum complexes as DNA-protein cross-linking agents.
Kloster M; Kostrhunova H; Zaludova R; Malina J; Kasparkova J; Brabec V; Farrell N
Biochemistry; 2004 Jun; 43(24):7776-86. PubMed ID: 15196020
[TBL] [Abstract][Full Text] [Related]
18. Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
Muchova T; Quintal SM; Farrell NP; Brabec V; Kasparkova J
J Biol Inorg Chem; 2012 Feb; 17(2):239-45. PubMed ID: 21938443
[TBL] [Abstract][Full Text] [Related]
19. Kinetic and equilibria studies of the aquation of the trinuclear platinum phase II anticancer agent [(trans-PtCl(NH(3))(2))(2)(mu-trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2))](4+) (BBR3464).
Davies MS; Thomas DS; Hegmans A; Berners-Price SJ; Farrell N
Inorg Chem; 2002 Mar; 41(5):1101-9. PubMed ID: 11874344
[TBL] [Abstract][Full Text] [Related]
20. Walking of antitumor bifunctional trinuclear PtII complex on double-helical DNA.
Malina J; Kasparkova J; Farrell NP; Brabec V
Nucleic Acids Res; 2011 Jan; 39(2):720-8. PubMed ID: 20833634
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]