172 related articles for article (PubMed ID: 19692352)
1. Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1.
Zhou J; Brugarolas J; Parada LF
Hum Mol Genet; 2009 Nov; 18(22):4428-41. PubMed ID: 19692352
[TBL] [Abstract][Full Text] [Related]
2. The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway.
Hartman TR; Liu D; Zilfou JT; Robb V; Morrison T; Watnick T; Henske EP
Hum Mol Genet; 2009 Jan; 18(1):151-63. PubMed ID: 18845692
[TBL] [Abstract][Full Text] [Related]
3. Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization.
Ren S; Luo Y; Chen H; Warburton D; Lam HC; Wang LL; Chen P; Henske EP; Shi W
Am J Pathol; 2016 Dec; 186(12):3261-3272. PubMed ID: 27768862
[TBL] [Abstract][Full Text] [Related]
4. Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner.
Bilanges B; Argonza-Barrett R; Kolesnichenko M; Skinner C; Nair M; Chen M; Stokoe D
Mol Cell Biol; 2007 Aug; 27(16):5746-64. PubMed ID: 17562867
[TBL] [Abstract][Full Text] [Related]
5. Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Chen J; Futami K; Petillo D; Peng J; Wang P; Knol J; Li Y; Khoo SK; Huang D; Qian CN; Zhao P; Dykema K; Zhang R; Cao B; Yang XJ; Furge K; Williams BO; Teh BT
PLoS One; 2008; 3(10):e3581. PubMed ID: 18974783
[TBL] [Abstract][Full Text] [Related]
6. Not all kidney cysts are created equal: a distinct renal cystogenic mechanism in tuberous sclerosis complex (TSC).
Soleimani M
Front Physiol; 2023; 14():1289388. PubMed ID: 38028758
[TBL] [Abstract][Full Text] [Related]
7. TSC1/TSC2 inactivation inhibits AKT through mTORC1-dependent up-regulation of STAT3-PTEN cascade.
Zha X; Hu Z; He S; Wang F; Shen H; Zhang H
Cancer Lett; 2011 Dec; 313(2):211-7. PubMed ID: 22055460
[TBL] [Abstract][Full Text] [Related]
8. mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex.
Pema M; Drusian L; Chiaravalli M; Castelli M; Yao Q; Ricciardi S; Somlo S; Qian F; Biffo S; Boletta A
Nat Commun; 2016 Mar; 7():10786. PubMed ID: 26931735
[TBL] [Abstract][Full Text] [Related]
9. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
Tanwar PS; Kaneko-Tarui T; Zhang L; Tanaka Y; Crum CP; Teixeira JM
PLoS Genet; 2012; 8(8):e1002906. PubMed ID: 22916036
[TBL] [Abstract][Full Text] [Related]
10. Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles.
Adhikari D; Zheng W; Shen Y; Gorre N; Hämäläinen T; Cooney AJ; Huhtaniemi I; Lan ZJ; Liu K
Hum Mol Genet; 2010 Feb; 19(3):397-410. PubMed ID: 19843540
[TBL] [Abstract][Full Text] [Related]
11. Renal tumours in a Tsc1+/- mouse model show epigenetic suppression of organic cation transporters Slc22a1, Slc22a2 and Slc22a3, and do not respond to metformin.
Yang J; Kalogerou M; Gallacher J; Sampson JR; Shen MH
Eur J Cancer; 2013 Apr; 49(6):1479-90. PubMed ID: 23228442
[TBL] [Abstract][Full Text] [Related]
12. Comparative analysis of Tsc1 and Tsc2 single and double radial glial cell mutants.
Mietzsch U; McKenna J; Reith RM; Way SW; Gambello MJ
J Comp Neurol; 2013 Nov; 521(16):3817-31. PubMed ID: 23749404
[TBL] [Abstract][Full Text] [Related]
13. Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.
Bonnet CS; Aldred M; von Ruhland C; Harris R; Sandford R; Cheadle JP
Hum Mol Genet; 2009 Jun; 18(12):2166-76. PubMed ID: 19321600
[TBL] [Abstract][Full Text] [Related]
14. Renal Neoplasia in Polycystic Kidney Disease: An Assessment of Tuberous Sclerosis Complex-associated Renal Neoplasia and PKD1/TSC2 Contiguous Gene Deletion Syndrome.
Gupta S; Lohse CM; Rowsey R; McCarthy MR; Shen W; Herrera-Hernandez L; Boorjian SA; Houston Thompson R; Jimenez RE; Leibovich BC; Cheville JC
Eur Urol; 2022 Mar; 81(3):229-233. PubMed ID: 34876325
[TBL] [Abstract][Full Text] [Related]
15. A genetic model to dissect the role of Tsc-mTORC1 in neuronal cultures.
Nie D; Sahin M
Methods Mol Biol; 2012; 821():393-405. PubMed ID: 22125080
[TBL] [Abstract][Full Text] [Related]
16. The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas.
Plank TL; Logginidou H; Klein-Szanto A; Henske EP
Mod Pathol; 1999 May; 12(5):539-45. PubMed ID: 10349994
[TBL] [Abstract][Full Text] [Related]
17. TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome.
Venkatesh A; Ma S; Punzo C
Cell Death Dis; 2016 Jun; 7(6):e2279. PubMed ID: 27362797
[TBL] [Abstract][Full Text] [Related]
18. Analysis of 65 tuberous sclerosis complex (TSC) patients by TSC2 DGGE, TSC1/TSC2 MLPA, and TSC1 long-range PCR sequencing, and report of 28 novel mutations.
Rendtorff ND; Bjerregaard B; Frödin M; Kjaergaard S; Hove H; Skovby F; Brøndum-Nielsen K; Schwartz M;
Hum Mutat; 2005 Oct; 26(4):374-83. PubMed ID: 16114042
[TBL] [Abstract][Full Text] [Related]
19. Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis.
Lacher MD; Pincheira R; Zhu Z; Camoretti-Mercado B; Matli M; Warren RS; Castro AF
Oncogene; 2010 Dec; 29(50):6543-56. PubMed ID: 20818424
[TBL] [Abstract][Full Text] [Related]
20. Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.
Armour EA; Carson RP; Ess KC
Am J Physiol Renal Physiol; 2012 Aug; 303(4):F584-92. PubMed ID: 22674026
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]