135 related articles for article (PubMed ID: 19695222)
1. Regulation of folliculin (the BHD gene product) phosphorylation by Tsc2-mTOR pathway.
Piao X; Kobayashi T; Wang L; Shiono M; Takagi Y; Sun G; Abe M; Hagiwara Y; Zhang D; Okimoto K; Kouchi M; Matsumoto I; Hino O
Biochem Biophys Res Commun; 2009 Nov; 389(1):16-21. PubMed ID: 19695222
[TBL] [Abstract][Full Text] [Related]
2. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
Baba M; Hong SB; Sharma N; Warren MB; Nickerson ML; Iwamatsu A; Esposito D; Gillette WK; Hopkins RF; Hartley JL; Furihata M; Oishi S; Zhen W; Burke TR; Linehan WM; Schmidt LS; Zbar B
Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15552-7. PubMed ID: 17028174
[TBL] [Abstract][Full Text] [Related]
3. Serine 62 is a phosphorylation site in folliculin, the Birt-Hogg-Dubé gene product.
Wang L; Kobayashi T; Piao X; Shiono M; Takagi Y; Mineki R; Taka H; Zhang D; Abe M; Sun G; Hagiwara Y; Okimoto K; Matsumoto I; Kouchi M; Hino O
FEBS Lett; 2010 Jan; 584(1):39-43. PubMed ID: 19914239
[TBL] [Abstract][Full Text] [Related]
4. Interaction of folliculin (Birt-Hogg-Dubé gene product) with a novel Fnip1-like (FnipL/Fnip2) protein.
Takagi Y; Kobayashi T; Shiono M; Wang L; Piao X; Sun G; Zhang D; Abe M; Hagiwara Y; Takahashi K; Hino O
Oncogene; 2008 Sep; 27(40):5339-47. PubMed ID: 18663353
[TBL] [Abstract][Full Text] [Related]
5. Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex.
Nellist M; Sancak O; Goedbloed MA; Rohe C; van Netten D; Mayer K; Tucker-Williams A; van den Ouweland AM; Halley DJ
Eur J Hum Genet; 2005 Jan; 13(1):59-68. PubMed ID: 15483652
[TBL] [Abstract][Full Text] [Related]
6. Selective inhibition of growth of tuberous sclerosis complex 2 null cells by atorvastatin is associated with impaired Rheb and Rho GTPase function and reduced mTOR/S6 kinase activity.
Finlay GA; Malhowski AJ; Liu Y; Fanburg BL; Kwiatkowski DJ; Toksoz D
Cancer Res; 2007 Oct; 67(20):9878-86. PubMed ID: 17942919
[TBL] [Abstract][Full Text] [Related]
7. Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
Hudon V; Sabourin S; Dydensborg AB; Kottis V; Ghazi A; Paquet M; Crosby K; Pomerleau V; Uetani N; Pause A
J Med Genet; 2010 Mar; 47(3):182-9. PubMed ID: 19843504
[TBL] [Abstract][Full Text] [Related]
8. Rheb binds and regulates the mTOR kinase.
Long X; Lin Y; Ortiz-Vega S; Yonezawa K; Avruch J
Curr Biol; 2005 Apr; 15(8):702-13. PubMed ID: 15854902
[TBL] [Abstract][Full Text] [Related]
9. Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis.
Lacher MD; Pincheira R; Zhu Z; Camoretti-Mercado B; Matli M; Warren RS; Castro AF
Oncogene; 2010 Dec; 29(50):6543-56. PubMed ID: 20818424
[TBL] [Abstract][Full Text] [Related]
10. The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition.
Shiono M; Kobayashi T; Takahashi R; Sun G; Abe M; Zhang D; Wang L; Piao X; Takagi Y; Mineki R; Taka H; Tada N; Sonobe S; Momose S; Ueda M; Hino O
Oncogene; 2008 Nov; 27(52):6690-7. PubMed ID: 18695678
[TBL] [Abstract][Full Text] [Related]
11. Tuberin activates and controls the distribution of Rac1 via association with p62 and ubiquitin through the mTORC1 signaling pathway.
Okura H; Kobayashi T; Koike M; Ohsawa M; Zhang D; Arai H; Uchiyama Y; Hino O
Int J Oncol; 2013 Aug; 43(2):447-56. PubMed ID: 23759924
[TBL] [Abstract][Full Text] [Related]
12. Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).
Lu X; Boora U; Seabra L; Rabai EM; Fenton J; Reiman A; Nagy Z; Maher ER
Oncogene; 2014 Feb; 33(8):956-65. PubMed ID: 23416984
[TBL] [Abstract][Full Text] [Related]
13. Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia.
Zhong M; Zhao X; Li J; Yuan W; Yan G; Tong M; Guo S; Zhu Y; Jiang Y; Liu Y; Jiang Y
J Biol Chem; 2016 May; 291(22):11689-97. PubMed ID: 27072130
[TBL] [Abstract][Full Text] [Related]
14. The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Wada S; Neinast M; Jang C; Ibrahim YH; Lee G; Babu A; Li J; Hoshino A; Rowe GC; Rhee J; Martina JA; Puertollano R; Blenis J; Morley M; Baur JA; Seale P; Arany Z
Genes Dev; 2016 Nov; 30(22):2551-2564. PubMed ID: 27913603
[TBL] [Abstract][Full Text] [Related]
15. Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation.
Uhlmann EJ; Li W; Scheidenhelm DK; Gau CL; Tamanoi F; Gutmann DH
Glia; 2004 Aug; 47(2):180-8. PubMed ID: 15185396
[TBL] [Abstract][Full Text] [Related]
16. Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain.
Yu J; Henske EP
Cancer Res; 2006 Oct; 66(19):9461-6. PubMed ID: 17018601
[TBL] [Abstract][Full Text] [Related]
17. Unique mutation, accelerated mTOR signaling and angiogenesis in the pulmonary cysts of Birt-Hogg-Dubé syndrome.
Nishii T; Tanabe M; Tanaka R; Matsuzawa T; Okudela K; Nozawa A; Nakatani Y; Furuya M
Pathol Int; 2013 Jan; 63(1):45-55. PubMed ID: 23356225
[TBL] [Abstract][Full Text] [Related]
18. Loss of the Birt-Hogg-Dubé gene product folliculin induces longevity in a hypoxia-inducible factor-dependent manner.
Gharbi H; Fabretti F; Bharill P; Rinschen MM; Brinkkötter S; Frommolt P; Burst V; Schermer B; Benzing T; Müller RU
Aging Cell; 2013 Aug; 12(4):593-603. PubMed ID: 23566034
[TBL] [Abstract][Full Text] [Related]
19. Rheb fills a GAP between TSC and TOR.
Manning BD; Cantley LC
Trends Biochem Sci; 2003 Nov; 28(11):573-6. PubMed ID: 14607085
[TBL] [Abstract][Full Text] [Related]
20. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.
Petit CS; Roczniak-Ferguson A; Ferguson SM
J Cell Biol; 2013 Sep; 202(7):1107-22. PubMed ID: 24081491
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
