BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

218 related articles for article (PubMed ID: 19706322)

  • 21. Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile salt export pump (Bsep) by troglitazone and troglitazone sulfate.
    Funk C; Pantze M; Jehle L; Ponelle C; Scheuermann G; Lazendic M; Gasser R
    Toxicology; 2001 Oct; 167(1):83-98. PubMed ID: 11557132
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hepatocyte-based in vitro model for assessment of drug-induced cholestasis.
    Chatterjee S; Richert L; Augustijns P; Annaert P
    Toxicol Appl Pharmacol; 2014 Jan; 274(1):124-36. PubMed ID: 24211272
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The role of the sodium-taurocholate cotransporting polypeptide (NTCP) and of the bile salt export pump (BSEP) in physiology and pathophysiology of bile formation.
    Stieger B
    Handb Exp Pharmacol; 2011; (201):205-59. PubMed ID: 21103971
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats.
    Kostrubsky VE; Strom SC; Hanson J; Urda E; Rose K; Burliegh J; Zocharski P; Cai H; Sinclair JF; Sahi J
    Toxicol Sci; 2003 Nov; 76(1):220-8. PubMed ID: 12944587
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Short-term feedback regulation of bile salt uptake by bile salts in rodent liver.
    Mühlfeld S; Domanova O; Berlage T; Stross C; Helmer A; Keitel V; Häussinger D; Kubitz R
    Hepatology; 2012 Dec; 56(6):2387-97. PubMed ID: 22806967
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Sulindac and its metabolites inhibit multiple transport proteins in rat and human hepatocytes.
    Lee JK; Paine MF; Brouwer KL
    J Pharmacol Exp Ther; 2010 Aug; 334(2):410-8. PubMed ID: 20430841
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Hepatocellular exposure of troglitazone metabolites in rat sandwich-cultured hepatocytes lacking Bcrp and Mrp2: interplay between formation and excretion.
    Yang K; Brouwer KL
    Drug Metab Dispos; 2014 Jul; 42(7):1219-26. PubMed ID: 24799397
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Xenobiotics inhibit hepatic uptake and biliary excretion of taurocholate in rat hepatocytes.
    Kemp DC; Zamek-Gliszczynski MJ; Brouwer KL
    Toxicol Sci; 2005 Feb; 83(2):207-14. PubMed ID: 15509663
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Hepatobiliary disposition of troglitazone and metabolites in rat and human sandwich-cultured hepatocytes: use of Monte Carlo simulations to assess the impact of changes in biliary excretion on troglitazone sulfate accumulation.
    Lee JK; Marion TL; Abe K; Lim C; Pollock GM; Brouwer KL
    J Pharmacol Exp Ther; 2010 Jan; 332(1):26-34. PubMed ID: 19801447
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.
    Yanni SB; Augustijns PF; Benjamin DK; Brouwer KL; Thakker DR; Annaert PP
    Drug Metab Dispos; 2010 Oct; 38(10):1848-56. PubMed ID: 20606004
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications.
    Ali I; Khalid S; Stieger B; Brouwer KLR
    Mol Pharm; 2019 Mar; 16(3):1406-1411. PubMed ID: 30608704
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors.
    Saran C; Sundqvist L; Ho H; Niskanen J; Honkakoski P; Brouwer KLR
    J Pharmacol Exp Ther; 2022 Feb; 380(2):114-125. PubMed ID: 34794962
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes.
    Ogimura E; Sekine S; Horie T
    Biochem Biophys Res Commun; 2011 Dec; 416(3-4):313-7. PubMed ID: 22108051
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver.
    Stieger B; Fattinger K; Madon J; Kullak-Ublick GA; Meier PJ
    Gastroenterology; 2000 Feb; 118(2):422-30. PubMed ID: 10648470
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Identification of hepatic phospholipidosis inducers in sandwich-cultured rat hepatocytes, a physiologically relevant model, reveals altered basolateral uptake and biliary excretion of anionic probe substrates.
    Ferslew BC; Brouwer KL
    Toxicol Sci; 2014 May; 139(1):99-107. PubMed ID: 24563379
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration.
    Liu X; LeCluyse EL; Brouwer KR; Gan LS; Lemasters JJ; Stieger B; Meier PJ; Brouwer KL
    Am J Physiol; 1999 Jul; 277(1):G12-21. PubMed ID: 10409146
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Hepatobiliary disposition in primary cultures of dog and monkey hepatocytes.
    Rose KA; Kostrubsky V; Sahi J
    Mol Pharm; 2006; 3(3):266-74. PubMed ID: 16749858
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification of Bile Acids Responsible for Inhibiting the Bile Salt Export Pump, Leading to Bile Acid Accumulation and Cell Toxicity in Rat Hepatocytes.
    Oizumi K; Sekine S; Fukagai M; Susukida T; Ito K
    J Pharm Sci; 2017 Sep; 106(9):2412-2419. PubMed ID: 28552691
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Development of a Rat Sandwich-Cultured Hepatocytes Model Expressing Functional Human Organic Anion Transporting Polypeptide (OATP) 1B3: A Potential Screening Tool for Liver-Targeting Compounds.
    Farasyn T; Xu C; Yue W
    J Pharm Pharm Sci; 2021; 24():475-483. PubMed ID: 34516949
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Basal efflux of bile acids contributes to drug-induced bile acid-dependent hepatocyte toxicity in rat sandwich-cultured hepatocytes.
    Susukida T; Sekine S; Ogimura E; Aoki S; Oizumi K; Horie T; Ito K
    Toxicol In Vitro; 2015 Oct; 29(7):1454-63. PubMed ID: 26055650
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.