BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

300 related articles for article (PubMed ID: 19706524)

  • 1. Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.
    Wu X; Ge H; Lemon B; Weiszmann J; Gupte J; Hawkins N; Li X; Tang J; Lindberg R; Li Y
    Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14379-84. PubMed ID: 19706524
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB.
    Yang C; Jin C; Li X; Wang F; McKeehan WL; Luo Y
    PLoS One; 2012; 7(3):e33870. PubMed ID: 22442730
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.
    Wu AL; Coulter S; Liddle C; Wong A; Eastham-Anderson J; French DM; Peterson AS; Sonoda J
    PLoS One; 2011 Mar; 6(3):e17868. PubMed ID: 21437243
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation.
    Luo Y; Yang C; Lu W; Xie R; Jin C; Huang P; Wang F; McKeehan WL
    J Biol Chem; 2010 Sep; 285(39):30069-78. PubMed ID: 20657013
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A unique FGF23 with the ability to activate FGFR signaling through both αKlotho and βKlotho.
    Wu X; Weiszmann J; Ge H; Baribault H; Stevens J; Hawkins N; Vonderfecht S; Gardner J; Gupte J; Sheng J; Wang M; Li Y
    J Mol Biol; 2012 Apr; 418(1-2):82-9. PubMed ID: 22370560
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of a FGF19 variant with altered receptor specificity revealed a central role for FGFR1c in the regulation of glucose metabolism.
    Ge H; Baribault H; Vonderfecht S; Lemon B; Weiszmann J; Gardner J; Lee KJ; Gupte J; Mookherjee P; Wang M; Sheng J; Wu X; Li Y
    PLoS One; 2012; 7(3):e33603. PubMed ID: 22457778
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression profile and overexpression outcome indicate a role for βKlotho in skeletal muscle fibro/adipogenesis.
    Phelps M; Stuelsatz P; Yablonka-Reuveni Z
    FEBS J; 2016 May; 283(9):1653-68. PubMed ID: 26881702
    [TBL] [Abstract][Full Text] [Related]  

  • 8. betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.
    Suzuki M; Uehara Y; Motomura-Matsuzaka K; Oki J; Koyama Y; Kimura M; Asada M; Komi-Kuramochi A; Oka S; Imamura T
    Mol Endocrinol; 2008 Apr; 22(4):1006-14. PubMed ID: 18187602
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21.
    Gupte J; Yang L; Wu X; Weiszmann J; Hecht R; Lemon B; Lindberg R; Wang Z; Li Y
    J Mol Biol; 2011 May; 408(3):491-502. PubMed ID: 21392510
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho.
    Nakamura M; Uehara Y; Asada M; Honda E; Nagai N; Kimata K; Suzuki M; Imamura T
    J Biol Chem; 2011 Jul; 286(30):26418-23. PubMed ID: 21653700
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation.
    Wu X; Ge H; Lemon B; Vonderfecht S; Weiszmann J; Hecht R; Gupte J; Hager T; Wang Z; Lindberg R; Li Y
    J Biol Chem; 2010 Feb; 285(8):5165-70. PubMed ID: 20018895
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lack of overt FGF21 resistance in two mouse models of obesity and insulin resistance.
    Hale C; Chen MM; Stanislaus S; Chinookoswong N; Hager T; Wang M; Véniant MM; Xu J
    Endocrinology; 2012 Jan; 153(1):69-80. PubMed ID: 22067317
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.
    Kurosu H; Choi M; Ogawa Y; Dickson AS; Goetz R; Eliseenkova AV; Mohammadi M; Rosenblatt KP; Kliewer SA; Kuro-O M
    J Biol Chem; 2007 Sep; 282(37):26687-26695. PubMed ID: 17623664
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Co-receptor requirements for fibroblast growth factor-19 signaling.
    Wu X; Ge H; Gupte J; Weiszmann J; Shimamoto G; Stevens J; Hawkins N; Lemon B; Shen W; Xu J; Veniant MM; Li YS; Lindberg R; Chen JL; Tian H; Li Y
    J Biol Chem; 2007 Oct; 282(40):29069-72. PubMed ID: 17711860
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A gut-brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus.
    Liu S; Marcelin G; Blouet C; Jeong JH; Jo YH; Schwartz GJ; Chua S
    Mol Metab; 2018 Feb; 8():37-50. PubMed ID: 29290621
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action.
    Zhang J; Gupte J; Gong Y; Weiszmann J; Zhang Y; Lee KJ; Richards WG; Li Y
    EBioMedicine; 2017 Feb; 15():173-183. PubMed ID: 28041926
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity.
    Wang C; Yang C; Chang JY; You P; Li Y; Jin C; Luo Y; Li X; McKeehan WL; Wang F
    Curr Mol Med; 2014; 14(6):703-711. PubMed ID: 25056539
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of FGF19 induced FGFR4 activation in the regulation of glucose homeostasis.
    Wu X; Li Y
    Aging (Albany NY); 2009 Dec; 1(12):1023-7. PubMed ID: 20157585
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity.
    Agrawal A; Parlee S; Perez-Tilve D; Li P; Pan J; Mroz PA; Kruse Hansen AM; Andersen B; Finan B; Kharitonenkov A; DiMarchi RD
    Mol Metab; 2018 Jul; 13():45-55. PubMed ID: 29789271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Making way for suppressing the FGF19/FGFR4 axis in cancer.
    Prieto-Dominguez N; Shull AY; Teng Y
    Future Med Chem; 2018 Oct; 10(20):2457-2470. PubMed ID: 30325210
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.