367 related articles for article (PubMed ID: 19706527)
1. The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor.
Rong YP; Bultynck G; Aromolaran AS; Zhong F; Parys JB; De Smedt H; Mignery GA; Roderick HL; Bootman MD; Distelhorst CW
Proc Natl Acad Sci U S A; 2009 Aug; 106(34):14397-402. PubMed ID: 19706527
[TBL] [Abstract][Full Text] [Related]
2. A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function.
Monaco G; La Rovere R; Karamanou S; Welkenhuyzen K; Ivanova H; Vandermarliere E; Di Martile M; Del Bufalo D; De Smedt H; Parys JB; Economou A; Bultynck G
FEBS J; 2018 Jan; 285(1):127-145. PubMed ID: 29131545
[TBL] [Abstract][Full Text] [Related]
3. Selective regulation of IP3-receptor-mediated Ca2+ signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl.
Monaco G; Decrock E; Akl H; Ponsaerts R; Vervliet T; Luyten T; De Maeyer M; Missiaen L; Distelhorst CW; De Smedt H; Parys JB; Leybaert L; Bultynck G
Cell Death Differ; 2012 Feb; 19(2):295-309. PubMed ID: 21818117
[TBL] [Abstract][Full Text] [Related]
4. Targeting Bcl-2-IP
Distelhorst CW
Biochim Biophys Acta Mol Cell Res; 2018 Nov; 1865(11 Pt B):1795-1804. PubMed ID: 30053503
[TBL] [Abstract][Full Text] [Related]
5. Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals.
Rong YP; Aromolaran AS; Bultynck G; Zhong F; Li X; McColl K; Matsuyama S; Herlitze S; Roderick HL; Bootman MD; Mignery GA; Parys JB; De Smedt H; Distelhorst CW
Mol Cell; 2008 Jul; 31(2):255-65. PubMed ID: 18657507
[TBL] [Abstract][Full Text] [Related]
6. Induction of Ca²+-driven apoptosis in chronic lymphocytic leukemia cells by peptide-mediated disruption of Bcl-2-IP3 receptor interaction.
Zhong F; Harr MW; Bultynck G; Monaco G; Parys JB; De Smedt H; Rong YP; Molitoris JK; Lam M; Ryder C; Matsuyama S; Distelhorst CW
Blood; 2011 Mar; 117(10):2924-34. PubMed ID: 21193695
[TBL] [Abstract][Full Text] [Related]
7. A dual role for the anti-apoptotic Bcl-2 protein in cancer: mitochondria versus endoplasmic reticulum.
Akl H; Vervloessem T; Kiviluoto S; Bittremieux M; Parys JB; De Smedt H; Bultynck G
Biochim Biophys Acta; 2014 Oct; 1843(10):2240-52. PubMed ID: 24768714
[TBL] [Abstract][Full Text] [Related]
8. Targeting Bcl-2 based on the interaction of its BH4 domain with the inositol 1,4,5-trisphosphate receptor.
Rong YP; Barr P; Yee VC; Distelhorst CW
Biochim Biophys Acta; 2009 Jun; 1793(6):971-8. PubMed ID: 19056433
[TBL] [Abstract][Full Text] [Related]
9. Alpha-helical destabilization of the Bcl-2-BH4-domain peptide abolishes its ability to inhibit the IP3 receptor.
Monaco G; Decrock E; Nuyts K; Wagner LE; Luyten T; Strelkov SV; Missiaen L; De Borggraeve WM; Leybaert L; Yule DI; De Smedt H; Parys JB; Bultynck G
PLoS One; 2013; 8(8):e73386. PubMed ID: 24137498
[TBL] [Abstract][Full Text] [Related]
10. Bcl-2 and IP
Ivanova H; Wagner LE; Tanimura A; Vandermarliere E; Luyten T; Welkenhuyzen K; Alzayady KJ; Wang L; Hamada K; Mikoshiba K; De Smedt H; Martens L; Yule DI; Parys JB; Bultynck G
Cell Mol Life Sci; 2019 Oct; 76(19):3843-3859. PubMed ID: 30989245
[TBL] [Abstract][Full Text] [Related]
11. The BH4 domain of Bcl-2 orthologues from different classes of vertebrates can act as an evolutionary conserved inhibitor of IP
Ivanova H; Luyten T; Decrock E; Vervliet T; Leybaert L; Parys JB; Bultynck G
Cell Calcium; 2017 Mar; 62():41-46. PubMed ID: 28179071
[TBL] [Abstract][Full Text] [Related]
12. IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.
Akl H; Monaco G; La Rovere R; Welkenhuyzen K; Kiviluoto S; Vervliet T; Molgó J; Distelhorst CW; Missiaen L; Mikoshiba K; Parys JB; De Smedt H; Bultynck G
Cell Death Dis; 2013 May; 4(5):e632. PubMed ID: 23681227
[TBL] [Abstract][Full Text] [Related]
13. The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.
Schulman JJ; Wright FA; Kaufmann T; Wojcikiewicz RJH
J Biol Chem; 2013 Aug; 288(35):25340-25349. PubMed ID: 23884412
[TBL] [Abstract][Full Text] [Related]
14. The selective BH4-domain biology of Bcl-2-family members: IP3Rs and beyond.
Monaco G; Vervliet T; Akl H; Bultynck G
Cell Mol Life Sci; 2013 Apr; 70(7):1171-83. PubMed ID: 22955373
[TBL] [Abstract][Full Text] [Related]
15. Constitutive IP
Bittremieux M; La Rovere RM; Akl H; Martines C; Welkenhuyzen K; Dubron K; Baes M; Janssens A; Vandenberghe P; Laurenti L; Rietdorf K; Morciano G; Pinton P; Mikoshiba K; Bootman MD; Efremov DG; De Smedt H; Parys JB; Bultynck G
Cell Death Differ; 2019 Mar; 26(3):531-547. PubMed ID: 29899382
[TBL] [Abstract][Full Text] [Related]
16. The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.
Monaco G; Decrock E; Arbel N; van Vliet AR; La Rovere RM; De Smedt H; Parys JB; Agostinis P; Leybaert L; Shoshan-Barmatz V; Bultynck G
J Biol Chem; 2015 Apr; 290(14):9150-61. PubMed ID: 25681439
[TBL] [Abstract][Full Text] [Related]
17. Suppression of IP3-mediated calcium release and apoptosis by Bcl-2 involves the participation of protein phosphatase 1.
Xu L; Kong D; Zhu L; Zhu W; Andrews DW; Kuo TH
Mol Cell Biochem; 2007 Jan; 295(1-2):153-65. PubMed ID: 16874461
[TBL] [Abstract][Full Text] [Related]
18. HA14-1 potentiates apoptosis in B-cell cancer cells sensitive to a peptide disrupting IP 3 receptor / Bcl-2 complexes.
Akl H; La Rovere RM; Janssens A; Vandenberghe P; Parys JB; Bultynck G
Int J Dev Biol; 2015; 59(7-9):391-8. PubMed ID: 26260683
[TBL] [Abstract][Full Text] [Related]
19. A synthetic peptide targeting the BH4 domain of Bcl-2 induces apoptosis in multiple myeloma and follicular lymphoma cells alone or in combination with agents targeting the BH3-binding pocket of Bcl-2.
Lavik AR; Zhong F; Chang MJ; Greenberg E; Choudhary Y; Smith MR; McColl KS; Pink J; Reu FJ; Matsuyama S; Distelhorst CW
Oncotarget; 2015 Sep; 6(29):27388-402. PubMed ID: 26317541
[TBL] [Abstract][Full Text] [Related]
20. Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling.
Eckenrode EF; Yang J; Velmurugan GV; Foskett JK; White C
J Biol Chem; 2010 Apr; 285(18):13678-84. PubMed ID: 20189983
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
