286 related articles for article (PubMed ID: 19709933)
1. PIKK-dependent phosphorylation of Mre11 induces MRN complex inactivation by disassembly from chromatin.
Di Virgilio M; Ying CY; Gautier J
DNA Repair (Amst); 2009 Nov; 8(11):1311-20. PubMed ID: 19709933
[TBL] [Abstract][Full Text] [Related]
2. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
[TBL] [Abstract][Full Text] [Related]
3. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
Duursma AM; Driscoll R; Elias JE; Cimprich KA
Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
[TBL] [Abstract][Full Text] [Related]
4. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
Williams RS; Williams JS; Tainer JA
Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
[TBL] [Abstract][Full Text] [Related]
5. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
[TBL] [Abstract][Full Text] [Related]
6. CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.
Ramírez-Lugo JS; Yoo HY; Yoon SJ; Dunphy WG
Cell Cycle; 2011 Feb; 10(3):469-80. PubMed ID: 21263215
[TBL] [Abstract][Full Text] [Related]
7. Ataxia telangiectasia-mutated (ATM) kinase activity is regulated by ATP-driven conformational changes in the Mre11/Rad50/Nbs1 (MRN) complex.
Lee JH; Mand MR; Deshpande RA; Kinoshita E; Yang SH; Wyman C; Paull TT
J Biol Chem; 2013 May; 288(18):12840-51. PubMed ID: 23525106
[TBL] [Abstract][Full Text] [Related]
8. Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex.
Dupré A; Boyer-Chatenet L; Gautier J
Nat Struct Mol Biol; 2006 May; 13(5):451-7. PubMed ID: 16622404
[TBL] [Abstract][Full Text] [Related]
9. The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.
Paull TT; Lee JH
Cell Cycle; 2005 Jun; 4(6):737-40. PubMed ID: 15908798
[TBL] [Abstract][Full Text] [Related]
10. The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks.
Lee J; Dunphy WG
Mol Biol Cell; 2013 May; 24(9):1343-53. PubMed ID: 23468519
[TBL] [Abstract][Full Text] [Related]
11. Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity.
Jazayeri A; Balestrini A; Garner E; Haber JE; Costanzo V
EMBO J; 2008 Jul; 27(14):1953-62. PubMed ID: 18596698
[TBL] [Abstract][Full Text] [Related]
12. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts.
Tatsukawa K; Sakamoto R; Kawasoe Y; Kubota Y; Tsurimoto T; Takahashi TS; Ohashi E
Nucleic Acids Res; 2024 Apr; 52(6):3146-3163. PubMed ID: 38349040
[TBL] [Abstract][Full Text] [Related]
13. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex.
Lee JH; Paull TT
Science; 2005 Apr; 308(5721):551-4. PubMed ID: 15790808
[TBL] [Abstract][Full Text] [Related]
14. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm.
Cerosaletti K; Concannon P
J Biol Chem; 2004 Sep; 279(37):38813-9. PubMed ID: 15234984
[TBL] [Abstract][Full Text] [Related]
15. ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks.
Trenz K; Smith E; Smith S; Costanzo V
EMBO J; 2006 Apr; 25(8):1764-74. PubMed ID: 16601701
[TBL] [Abstract][Full Text] [Related]
16. The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Yu Z; Vogel G; Coulombe Y; Dubeau D; Spehalski E; Hébert J; Ferguson DO; Masson JY; Richard S
Cell Res; 2012 Feb; 22(2):305-20. PubMed ID: 21826105
[TBL] [Abstract][Full Text] [Related]
17. Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11.
Chen C; Zhang L; Huang NJ; Huang B; Kornbluth S
Proc Natl Acad Sci U S A; 2013 Dec; 110(51):20605-10. PubMed ID: 24297933
[TBL] [Abstract][Full Text] [Related]
18. Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair.
Peterson SE; Li Y; Chait BT; Gottesman ME; Baer R; Gautier J
J Cell Biol; 2011 Sep; 194(5):705-20. PubMed ID: 21893598
[TBL] [Abstract][Full Text] [Related]
19. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks.
Lavin MF
Oncogene; 2007 Dec; 26(56):7749-58. PubMed ID: 18066087
[TBL] [Abstract][Full Text] [Related]
20. Rad50 zinc hook is important for the Mre11 complex to bind chromosomal DNA double-stranded breaks and initiate various DNA damage responses.
He J; Shi LZ; Truong LN; Lu CS; Razavian N; Li Y; Negrete A; Shiloach J; Berns MW; Wu X
J Biol Chem; 2012 Sep; 287(38):31747-56. PubMed ID: 22833675
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]