BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

176 related articles for article (PubMed ID: 19716293)

  • 1. Structure-activity relationship of isoform selective inhibitors of Rac1/1b GTPase nucleotide binding.
    Beausoleil E; Chauvignac C; Taverne T; Lacombe S; Pognante L; Leblond B; Pallares D; Oliveira CD; Bachelot F; Carton R; Peillon H; Coutadeur S; Picard V; Lambeng N; Désiré L; Schweighoffer F
    Bioorg Med Chem Lett; 2009 Oct; 19(19):5594-8. PubMed ID: 19716293
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Purification and biochemical properties of Rac1, 2, 3 and the splice variant Rac1b.
    Haeusler LC; Hemsath L; Fiegen D; Blumenstein L; Herbrand U; Stege P; Dvorsky R; Ahmadian MR
    Methods Enzymol; 2006; 406():1-11. PubMed ID: 16472645
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The use of surface plasmon resonance (SPR) and fluorescence resonance energy transfer (FRET) to monitor the interaction of the plant G-proteins Ms-Rac1 and Ms-Rac4 with GTP.
    Brecht M; Sewald K; Schiene K; Keen G; Fricke M; Sauer M; Niehaus K
    J Biotechnol; 2004 Aug; 112(1-2):151-64. PubMed ID: 15288950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Selective activation by the guanine nucleotide exchange factor Don1 is a main determinant of Cdc42 signalling specificity in Ustilago maydis.
    Hlubek A; Schink KO; Mahlert M; Sandrock B; Bölker M
    Mol Microbiol; 2008 May; 68(3):615-23. PubMed ID: 18394145
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Suppression of nuclear Wnt signaling leads to stabilization of Rac1 isoforms.
    Esufali S; Charames GS; Bapat B
    FEBS Lett; 2007 Oct; 581(25):4850-6. PubMed ID: 17888911
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation.
    Singh A; Karnoub AE; Palmby TR; Lengyel E; Sondek J; Der CJ
    Oncogene; 2004 Dec; 23(58):9369-80. PubMed ID: 15516977
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors.
    Jordan P; Brazåo R; Boavida MG; Gespach C; Chastre E
    Oncogene; 1999 Nov; 18(48):6835-9. PubMed ID: 10597294
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (1).
    Asano Y; Kitamura S; Ohra T; Aso K; Igata H; Tamura T; Kawamoto T; Tanaka T; Sogabe S; Matsumoto S; Yamaguchi M; Kimura H; Itoh F
    Bioorg Med Chem; 2008 Apr; 16(8):4715-32. PubMed ID: 18313304
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, in vitro and computational studies of protein tyrosine phosphatase 1B inhibition of a small library of 2-arylsulfonylaminobenzothiazoles with antihyperglycemic activity.
    Navarrete-Vazquez G; Paoli P; León-Rivera I; Villalobos-Molina R; Medina-Franco JL; Ortiz-Andrade R; Estrada-Soto S; Camici G; Diaz-Coutiño D; Gallardo-Ortiz I; Martinez-Mayorga K; Moreno-Díaz H
    Bioorg Med Chem; 2009 May; 17(9):3332-41. PubMed ID: 19362487
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploring the active site of phenylethanolamine N-methyltransferase with 3-hydroxyethyl- and 3-hydroxypropyl-7-substituted-1,2,3,4-tetrahydroisoquinolines.
    Grunewald GL; Romero FA; Seim MR; Criscione KR; Deupree JD; Spackman CC; Bylund DB
    Bioorg Med Chem Lett; 2005 Feb; 15(4):1143-7. PubMed ID: 15686930
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown.
    Baumer Y; Spindler V; Werthmann RC; Bünemann M; Waschke J
    J Cell Physiol; 2009 Sep; 220(3):716-26. PubMed ID: 19472214
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Virtual screening approach for the identification of new Rac1 inhibitors.
    Ferri N; Corsini A; Bottino P; Clerici F; Contini A
    J Med Chem; 2009 Jul; 52(14):4087-90. PubMed ID: 19527032
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery, synthesis and biological evaluation of isoquinolones as novel and highly selective JNK inhibitors (2).
    Asano Y; Kitamura S; Ohra T; Itoh F; Kajino M; Tamura T; Kaneko M; Ikeda S; Igata H; Kawamoto T; Sogabe S; Matsumoto S; Tanaka T; Yamaguchi M; Kimura H; Fukumoto S
    Bioorg Med Chem; 2008 Apr; 16(8):4699-714. PubMed ID: 18313930
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based optimization of benzoic acids as inhibitors of protein tyrosine phosphatase 1B and low molecular weight protein tyrosine phosphatase.
    Maccari R; Ottanà R; Ciurleo R; Paoli P; Manao G; Camici G; Laggner C; Langer T
    ChemMedChem; 2009 Jun; 4(6):957-62. PubMed ID: 19288492
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural and stereoelectronic requirements for the inhibition of mammalian 2,3-oxidosqualene cyclase by substituted isoquinoline derivatives.
    Barth MM; Binet JL; Thomas DM; de Fornel DC; Samreth S; Schuber FJ; Renaut PP
    J Med Chem; 1996 Jun; 39(12):2302-12. PubMed ID: 8691425
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process.
    Visvikis O; Lorès P; Boyer L; Chardin P; Lemichez E; Gacon G
    FEBS J; 2008 Jan; 275(2):386-96. PubMed ID: 18093184
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Berberine targets assembly of Escherichia coli cell division protein FtsZ.
    Domadia PN; Bhunia A; Sivaraman J; Swarup S; Dasgupta D
    Biochemistry; 2008 Mar; 47(10):3225-34. PubMed ID: 18275156
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereoselective HDAC inhibition from cysteine-derived zinc-binding groups.
    Butler KV; He R; McLaughlin K; Vistoli G; Langley B; Kozikowski AP
    ChemMedChem; 2009 Aug; 4(8):1292-301. PubMed ID: 19551801
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS.
    Koehn OJ; Lorimer E; Unger B; Harris R; Das AS; Suazo KF; Auger SA; Distefano MD; Prokop JW; Williams CL
    J Biol Chem; 2023 Jun; 299(6):104698. PubMed ID: 37059183
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.
    Onesto C; Shutes A; Picard V; Schweighoffer F; Der CJ
    Methods Enzymol; 2008; 439():111-29. PubMed ID: 18374160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.