BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

115 related articles for article (PubMed ID: 19717215)

  • 1. Synthesis and serotonin transporter activity of sulphur-substituted alpha-alkyl phenethylamines as a new class of anticancer agents.
    Cloonan SM; Keating JJ; Butler SG; Knox AJ; Jørgensen AM; Peters GH; Rai D; Corrigan D; Lloyd DG; Williams DC; Meegan MJ
    Eur J Med Chem; 2009 Dec; 44(12):4862-88. PubMed ID: 19717215
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.
    McNamara YM; Cloonan SM; Knox AJ; Keating JJ; Butler SG; Peters GH; Meegan MJ; Williams DC
    Bioorg Med Chem; 2011 Feb; 19(3):1328-48. PubMed ID: 21227702
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines.
    Cloonan SM; Keating JJ; Corrigan D; O'Brien JE; Kavanagh PV; Williams DC; Meegan MJ
    Bioorg Med Chem; 2010 Jun; 18(11):4009-31. PubMed ID: 20466553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and in vitro evaluation of novel derivatives of diphenylsulfide as serotonin transporter ligands.
    Vercouillie J; Mavel S; Galineau L; Ragusa T; Innis R; Kassiou M; Chalon S; Dollé F; Besnard JC; Guilloteau D; Emond P
    Bioorg Med Chem Lett; 2006 Mar; 16(5):1297-300. PubMed ID: 16337793
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fluorinated diaryl sulfides as serotonin transporter ligands: synthesis, structure-activity relationship study, and in vivo evaluation of fluorine-18-labeled compounds as PET imaging agents.
    Huang Y; Bae SA; Zhu Z; Guo N; Roth BL; Laruelle M
    J Med Chem; 2005 Apr; 48(7):2559-70. PubMed ID: 15801845
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of 1-boraadamantaneamine derivatives with selective astrocyte vs C6 glioma antiproliferative activity. A novel class of anti-hepatitis C agents with potential to bind CD81.
    Wagner CE; Mohler ML; Kang GS; Miller DD; Geisert EE; Chang YA; Fleischer EB; Shea KJ
    J Med Chem; 2003 Jul; 46(14):2823-33. PubMed ID: 12825926
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Further structural exploration of trisubstituted asymmetric pyran derivatives (2S,4R,5R)-2-benzhydryl-5-benzylamino-tetrahydropyran-4-ol and their corresponding disubstituted (3S,6S) pyran derivatives: a proposed pharmacophore model for high-affinity interaction with the dopamine, serotonin, and norepinephrine transporters.
    Zhang S; Fernandez F; Hazeldine S; Deschamps J; Zhen J; Reith ME; Dutta AK
    J Med Chem; 2006 Jul; 49(14):4239-47. PubMed ID: 16821783
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of the antiproliferative activity of novel isoindolo[2,1-a]quinoxaline and indolo[1,2-a]quinoxaline derivatives.
    Desplat V; Moreau S; Belisle-Fabre S; Thiolat D; Uranga J; Lucas R; de Moor L; Massip S; Jarry C; Mossalayi DM; Sonnet P; Déléris G; Guillon J
    J Enzyme Inhib Med Chem; 2011 Oct; 26(5):657-67. PubMed ID: 21250818
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
    Dutta AK; Xu C; Reith ME
    J Med Chem; 1998 Aug; 41(17):3293-7. PubMed ID: 9703474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biaryl analogues of conformationally constrained tricyclic tropanes as potent and selective norepinephrine reuptake inhibitors: synthesis and evaluation of their uptake inhibition at monoamine transporter sites.
    Zhou J; Zhang A; Kläss T; Johnson KM; Wang CZ; Ye YP; Kozikowski AP
    J Med Chem; 2003 May; 46(10):1997-2007. PubMed ID: 12723962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics.
    Meredith EJ; Holder MJ; Chamba A; Challa A; Drake-Lee A; Bunce CM; Drayson MT; Pilkington G; Blakely RD; Dyer MJ; Barnes NM; Gordon J
    FASEB J; 2005 Jul; 19(9):1187-9. PubMed ID: 15870169
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands.
    Jarkas N; Voll RJ; Williams L; Votaw JR; Owens M; Goodman MM
    J Med Chem; 2008 Jan; 51(2):271-81. PubMed ID: 18085744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of novel amino-substituted xanthenones and benzo[b]xanthenones: evaluation of their antiproliferative activity and their ability to overcome multidrug resistance toward MES-SA/D x 5 cells.
    Kostakis IK; Pouli N; Marakos P; Skaltsounis AL; Pratsinis H; Kletsas D
    Bioorg Med Chem; 2006 May; 14(9):2910-34. PubMed ID: 16376546
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Kulkarni SS; Grundt P; Kopajtic T; Katz JL; Newman AH
    J Med Chem; 2004 Jun; 47(13):3388-98. PubMed ID: 15189035
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of distamycin analogues - new potential anticancer agents.
    Drozdowska D; Rusak M; Miltyk W; Midura-Nowaczek K
    Arch Pharm (Weinheim); 2009 Feb; 342(2):87-93. PubMed ID: 19173336
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Syntheses of novel heterocycles as anticancer agents.
    Chauhan PM; Martins CJ; Horwell DC
    Bioorg Med Chem; 2005 May; 13(10):3513-8. PubMed ID: 15848764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel 5-(2-hydroxyphenyl)-3-substituted-2,3-dihydro-1,3,4-oxadiazole-2-thione derivatives: promising anticancer agents.
    Aboraia AS; Abdel-Rahman HM; Mahfouz NM; El-Gendy MA
    Bioorg Med Chem; 2006 Feb; 14(4):1236-46. PubMed ID: 16242340
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular modeling of potential new and selective PET radiotracers for the serotonin transporter. Positron Emission Tomography.
    Wellsow J; Kovar KA; Machulla HJ
    J Pharm Pharm Sci; 2002; 5(3):245-57. PubMed ID: 12553893
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and in vitro cytotoxicity evaluation of novel naphthindolizinedione derivatives.
    Defant A; Guella G; Mancini I
    Arch Pharm (Weinheim); 2007 Mar; 340(3):147-53. PubMed ID: 17315260
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and antiproliferative activity of some new azapyranoxanthenone aminoderivatives.
    Kolokythas G; Pouli N; Marakos P; Pratsinis H; Kletsas D
    Eur J Med Chem; 2006 Jan; 41(1):71-9. PubMed ID: 16300857
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.