133 related articles for article (PubMed ID: 19717303)
21. [Design, synthesis and biologic evaluation of diarylbenzimidazole derivatives as novel HIV-1 non-nucleoside reverse transcriptase inhibitors].
Qin BJ; Zhou T; Lu H; Jiang SB; Xie L
Yao Xue Xue Bao; 2009 Nov; 44(11):1233-43. PubMed ID: 21355324
[TBL] [Abstract][Full Text] [Related]
22. 2-(Aryl)-3-furan-2-ylmethyl-thiazolidin-4-ones as selective HIV-RT inhibitors.
Rawal RK; Prabhakar YS; Katti SB; De Clercq E
Bioorg Med Chem; 2005 Dec; 13(24):6771-6. PubMed ID: 16198576
[TBL] [Abstract][Full Text] [Related]
23. Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.
Yang S; Pannecouque C; Daelemans D; Ma XD; Liu Y; Chen FE; De Clercq E
Eur J Med Chem; 2013 Jul; 65():134-43. PubMed ID: 23707918
[TBL] [Abstract][Full Text] [Related]
24. Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants.
Su DS; Lim JJ; Tinney E; Wan BL; Young MB; Anderson KD; Rudd D; Munshi V; Bahnck C; Felock PJ; Lu M; Lai MT; Touch S; Moyer G; Distefano DJ; Flynn JA; Liang Y; Sanchez R; Prasad S; Yan Y; Perlow-Poehnelt R; Torrent M; Miller M; Vacca JP; Williams TM; Anthony NJ
Bioorg Med Chem Lett; 2009 Sep; 19(17):5119-23. PubMed ID: 19631528
[TBL] [Abstract][Full Text] [Related]
25. [The application of structural optimization strategies in drug design of HIV NNRTIs].
Wang L; Zhan P; Liu XY
Yao Xue Xue Bao; 2012 Nov; 47(11):1409-22. PubMed ID: 23387070
[TBL] [Abstract][Full Text] [Related]
26. Application of the Huisgen cycloaddition and 'click' reaction toward various 1,2,3-triazoles as HIV non-nucleoside reverse transcriptase inhibitors.
Pribut N; Veale CG; Basson AE; van Otterlo WA; Pelly SC
Bioorg Med Chem Lett; 2016 Aug; 26(15):3700-4. PubMed ID: 27287366
[TBL] [Abstract][Full Text] [Related]
27. Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
O'Meara JA; Jakalian A; LaPlante S; Bonneau PR; Coulombe R; Faucher AM; Guse I; Landry S; Racine J; Simoneau B; Thavonekham B; Yoakim C
Bioorg Med Chem Lett; 2007 Jun; 17(12):3362-6. PubMed ID: 17451954
[TBL] [Abstract][Full Text] [Related]
28. Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif.
Li W; Li X; De Clercq E; Zhan P; Liu X
Eur J Med Chem; 2015 Sep; 102():167-79. PubMed ID: 26276432
[TBL] [Abstract][Full Text] [Related]
29. Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1.
Wu B; Kuhen K; Ngoc Nguyen T; Ellis D; Anaclerio B; He X; Yang K; Karanewsky D; Yin H; Wolff K; Bieza K; Caldwell J; He Y
Bioorg Med Chem Lett; 2006 Jul; 16(13):3430-3. PubMed ID: 16632349
[TBL] [Abstract][Full Text] [Related]
30. Design, synthesis and biological evaluation of cycloalkyl arylpyrimidines (CAPYs) as HIV-1 NNRTIs.
Gu SX; Yang SQ; He QQ; Ma XD; Chen FE; Dai HF; Clercq ED; Balzarini J; Pannecouque C
Bioorg Med Chem; 2011 Dec; 19(23):7093-9. PubMed ID: 22037050
[TBL] [Abstract][Full Text] [Related]
31. Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses.
Tucker TJ; Sisko JT; Tynebor RM; Williams TM; Felock PJ; Flynn JA; Lai MT; Liang Y; McGaughey G; Liu M; Miller M; Moyer G; Munshi V; Perlow-Poehnelt R; Prasad S; Reid JC; Sanchez R; Torrent M; Vacca JP; Wan BL; Yan Y
J Med Chem; 2008 Oct; 51(20):6503-11. PubMed ID: 18826204
[TBL] [Abstract][Full Text] [Related]
32. From 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk](1,4)benzodiazepin-2(1H)-one (TIBO) to etravirine (TMC125): fifteen years of research on non-nucleoside inhibitors of HIV-1 reverse transcriptase.
De Corte BL
J Med Chem; 2005 Mar; 48(6):1689-96. PubMed ID: 15771411
[No Abstract] [Full Text] [Related]
33. Investigation of novel lipid-functionalized PNA monomers as potential HIV-1 non-nucleoside reverse transcriptase and/or integrase inhibitors.
Thomas MG; Maga G; Mouscadet JF; Howarth NM
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):1063-6. PubMed ID: 18058537
[TBL] [Abstract][Full Text] [Related]
34. Substituted indoles as HIV-1 non-nucleoside reverse transcriptase inhibitors: a patent evaluation (WO2015044928).
Li X; Gao P; Zhan P; Liu X
Expert Opin Ther Pat; 2016 May; 26(5):629-35. PubMed ID: 26742549
[TBL] [Abstract][Full Text] [Related]
35. Computational strategies in discovering novel non-nucleoside inhibitors of HIV-1 RT.
Barreca ML; Rao A; De Luca L; Zappalà M; Monforte AM; Maga G; Pannecouque C; Balzarini J; De Clercq E; Chimirri A; Monforte P
J Med Chem; 2005 May; 48(9):3433-7. PubMed ID: 15857150
[TBL] [Abstract][Full Text] [Related]
36. Design, synthesis, and preclinical evaluations of novel 4-substituted 1,5-diarylanilines as potent HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) drug candidates.
Sun LQ; Zhu L; Qian K; Qin B; Huang L; Chen CH; Lee KH; Xie L
J Med Chem; 2012 Aug; 55(16):7219-29. PubMed ID: 22856541
[TBL] [Abstract][Full Text] [Related]
37. Energetics of mutation-induced changes in potency of lersivirine against HIV-1 reverse transcriptase.
Kar P; Knecht V
J Phys Chem B; 2012 Jun; 116(22):6269-78. PubMed ID: 22574920
[TBL] [Abstract][Full Text] [Related]
38. Comparison of the non-nucleoside reverse transcriptase inhibitor lersivirine with its pyrazole and imidazole isomers.
Jones LH; Allan G; Corbau R; Middleton DS; Mowbray CE; Newman SD; Phillips C; Webster R; Westby M
Chem Biol Drug Des; 2011 May; 77(5):393-7. PubMed ID: 21352504
[TBL] [Abstract][Full Text] [Related]
39. Synthesis, biological evaluation and molecular modeling studies of new 2,3-diheteroaryl thiazolidin-4-ones as NNRTIs.
Debnath U; Verma S; Singh P; Rawat K; Gupta SK; Tripathi RK; Siddiqui HH; Katti SB; Prabhakar YS
Chem Biol Drug Des; 2015 Nov; 86(5):1285-91. PubMed ID: 26031778
[TBL] [Abstract][Full Text] [Related]
40. QSAR models for HEPT derivates as NNRTI inhibitors based on Monte Carlo method.
Toropova AP; Toropov AA; Veselinović JB; Miljković FN; Veselinović AM
Eur J Med Chem; 2014 Apr; 77():298-305. PubMed ID: 24657566
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]