280 related articles for article (PubMed ID: 19720877)
1. Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translation.
Hope HR; Anderson GD; Burnette BL; Compton RP; Devraj RV; Hirsch JL; Keith RH; Li X; Mbalaviele G; Messing DM; Saabye MJ; Schindler JF; Selness SR; Stillwell LI; Webb EG; Zhang J; Monahan JB
J Pharmacol Exp Ther; 2009 Dec; 331(3):882-95. PubMed ID: 19720877
[TBL] [Abstract][Full Text] [Related]
2. SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence.
Underwood DC; Osborn RR; Kotzer CJ; Adams JL; Lee JC; Webb EF; Carpenter DC; Bochnowicz S; Thomas HC; Hay DW; Griswold DE
J Pharmacol Exp Ther; 2000 Apr; 293(1):281-8. PubMed ID: 10734180
[TBL] [Abstract][Full Text] [Related]
3. Pharmacological effects of SB 220025, a selective inhibitor of P38 mitogen-activated protein kinase, in angiogenesis and chronic inflammatory disease models.
Jackson JR; Bolognese B; Hillegass L; Kassis S; Adams J; Griswold DE; Winkler JD
J Pharmacol Exp Ther; 1998 Feb; 284(2):687-92. PubMed ID: 9454815
[TBL] [Abstract][Full Text] [Related]
4. Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase.
Liverton NJ; Butcher JW; Claiborne CF; Claremon DA; Libby BE; Nguyen KT; Pitzenberger SM; Selnick HG; Smith GR; Tebben A; Vacca JP; Varga SL; Agarwal L; Dancheck K; Forsyth AJ; Fletcher DS; Frantz B; Hanlon WA; Harper CF; Hofsess SJ; Kostura M; Lin J; Luell S; O'Neill EA; O'Keefe SJ
J Med Chem; 1999 Jun; 42(12):2180-90. PubMed ID: 10377223
[TBL] [Abstract][Full Text] [Related]
5. Role of p38 mitogen-activated protein kinase in the healing of gastric ulcers in rats.
Kobayashi N; Kataoka T; Ono A; Tsukimi Y; Okabe S
J Physiol Pharmacol; 2001 Jun; 52(2):195-210. PubMed ID: 11453100
[TBL] [Abstract][Full Text] [Related]
6. PPA250 [3-(2,4-difluorophenyl)-6-[2-[4-(1H-imidazol-1-ylmethyl) phenoxy]ethoxy]-2-phenylpyridine], a novel orally effective inhibitor of the dimerization of inducible nitric-oxide synthase, exhibits an anti-inflammatory effect in animal models of chronic arthritis.
Ohtsuka M; Konno F; Honda H; Oikawa T; Ishikawa M; Iwase N; Isomae K; Ishii F; Hemmi H; Sato S
J Pharmacol Exp Ther; 2002 Oct; 303(1):52-7. PubMed ID: 12235232
[TBL] [Abstract][Full Text] [Related]
7. Inhibitors of p38 mitogen-activated protein kinase for the treatment of rheumatoid arthritis.
Pargellis C; Regan J
Curr Opin Investig Drugs; 2003 May; 4(5):566-71. PubMed ID: 12833650
[TBL] [Abstract][Full Text] [Related]
8. Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.
Bendele AM; Benslay DN; Hom JT; Spaethe SM; Ruterbories KJ; Lindstrom TD; Lee SJ; Naismith RW
J Pharmacol Exp Ther; 1992 Jan; 260(1):300-5. PubMed ID: 1309875
[TBL] [Abstract][Full Text] [Related]
9. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases.
Kumar S; Boehm J; Lee JC
Nat Rev Drug Discov; 2003 Sep; 2(9):717-26. PubMed ID: 12951578
[TBL] [Abstract][Full Text] [Related]
10. Effect of FR133605, a novel cytokine suppressive agent, on bone and cartilage destruction in adjuvant arthritic rats.
Yamamoto N; Sakai F; Yamazaki H; Kawai Y; Nakahara K; Okuhara M
J Rheumatol; 1996 Oct; 23(10):1778-83. PubMed ID: 8895158
[TBL] [Abstract][Full Text] [Related]
11. Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.
Laufer SA; Wagner GK; Kotschenreuther DA; Albrecht W
J Med Chem; 2003 Jul; 46(15):3230-44. PubMed ID: 12852754
[TBL] [Abstract][Full Text] [Related]
12. Potential of p38 inhibitors in the treatment of rheumatoid arthritis.
Foster ML; Halley F; Souness JE
Drug News Perspect; 2000 Oct; 13(8):488-97. PubMed ID: 12937622
[TBL] [Abstract][Full Text] [Related]
13. Biologic properties of romazarit (Ro 31-3948), a potential disease-modifying antirheumatic drug.
Bloxham DP; Bradshaw D; Cashin CH; Dodge BB; Lewis EJ; Westmacott D; Self CR
J Pharmacol Exp Ther; 1990 Mar; 252(3):1331-40. PubMed ID: 2156999
[TBL] [Abstract][Full Text] [Related]
14. 6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2, 3-b]pyridine (RWJ 68354): a potent and selective p38 kinase inhibitor.
Henry JR; Rupert KC; Dodd JH; Turchi IJ; Wadsworth SA; Cavender DE; Fahmy B; Olini GC; Davis JE; Pellegrino-Gensey JL; Schafer PH; Siekierka JJ
J Med Chem; 1998 Oct; 41(22):4196-8. PubMed ID: 9784093
[No Abstract] [Full Text] [Related]
15. Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis.
Badger AM; Griswold DE; Kapadia R; Blake S; Swift BA; Hoffman SJ; Stroup GB; Webb E; Rieman DJ; Gowen M; Boehm JC; Adams JL; Lee JC
Arthritis Rheum; 2000 Jan; 43(1):175-83. PubMed ID: 10643714
[TBL] [Abstract][Full Text] [Related]
16. Inflammatory mediators and stroke: new opportunities for novel therapeutics.
Barone FC; Feuerstein GZ
J Cereb Blood Flow Metab; 1999 Aug; 19(8):819-34. PubMed ID: 10458589
[TBL] [Abstract][Full Text] [Related]
17. Anti-inflammatory effects of ABT-702, a novel non-nucleoside adenosine kinase inhibitor, in rat adjuvant arthritis.
Boyle DL; Kowaluk EA; Jarvis MF; Lee CH; Bhagwat SS; Williams M; Firestein GS
J Pharmacol Exp Ther; 2001 Feb; 296(2):495-500. PubMed ID: 11160636
[TBL] [Abstract][Full Text] [Related]
18. Effects of a novel azaspirane (SK&F 105685) on arthritic lesions in the adjuvant Lewis rat: attenuation of the inflammatory process and preservation of skeletal integrity.
High WB; Bugelski PJ; Nichols ME; Swift BA; Solleveld HA; Badger AM
J Rheumatol; 1994 Mar; 21(3):476-83. PubMed ID: 8006892
[TBL] [Abstract][Full Text] [Related]
19. Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653.
Nishikawa M; Myoui A; Tomita T; Takahi K; Nampei A; Yoshikawa H
Arthritis Rheum; 2003 Sep; 48(9):2670-81. PubMed ID: 13130488
[TBL] [Abstract][Full Text] [Related]
20. ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse.
Jarvis MF; Yu H; Kohlhaas K; Alexander K; Lee CH; Jiang M; Bhagwat SS; Williams M; Kowaluk EA
J Pharmacol Exp Ther; 2000 Dec; 295(3):1156-64. PubMed ID: 11082453
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
